Personalized Medicine - turning drug development upside down!

Personalized Medicine - turning drug development upside down!

Dr Sharman has just posted his latest blog, in which he suspects he's offended medicinal chemists and drug developers with his grossly oversimplified version of the current anti-cancer drug development story and describes how we are leaving the "drug led" process into a "diagnostic led" period called personalized medicine.

Dr Sharman also recommends reading The Emperor of All Maladies, which was written by one of his residency classmates and was awarded the Pulitzer Prize.

Now to survive long enough and prosper well enough so I can afford the newly developed medicines. Meanwhile, I see my local library has that recommended book available for loan, so that's now on my reading list!


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  • It is worth noting that within this excellent blog posting from Dr Sharman is a link to a four part video on YouTube.

    The video is encouraging and is a recording of a lecture.

    I copy the link again below:-


  • Thanks Dick for reviewing and highlighting Dr. Sharman's videoed address to the Leukemia and Lymphoma Society on the history of cancer treatment and what's to come. This is certainly an interesting, entertaining and positive video that is well worth the ~50 minutes to watch.

    Here are the other parts:

    Part 2

    Part 3

    Part 4

    I note that Dr Sharman challenges the Leukemia and Lymphoma Society to sponsor sequencing of Lymphoma genomes (about US$10 - 15,000 per genome) in order to identify common genetic mutations that can be used as targets for new drugs...


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