ezetrol?: Hi ,,, has anyone had... - Cholesterol Support

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ezetrol?

jillgloucester profile image
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Hi ,,, has anyone had experience of taking Ezetrol?? Apparently it does the same as Statins but without so many side effects??

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jillgloucester
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10 Replies

No side effects?

nhs.uk/medicine-guides/page...

spats profile image
spats

YES and no better and maybe a little worse than statins. I am VERY likely to get severe side effects to many medications! Basically you have to give anything a try and make your own mind up as to treatment effect and life discomfort if you do get side effects. It took nine days for the pains to crack in, so fairly soon to let you start making decisions!!!

Richbod profile image
Richbod in reply to spats

You sound very similar to me spats. I can't take many medicines to help with my cholesterol prblem- I can get away with Maxepa capsules to help with the lypids, and I am now experiencing problems with BP medications too. The side effects to me vastly outweigh any potential benefits!!!!!!! Good luck

Richbod

Richbod profile image
Richbod

I have tried ezetrol (twice). The second time was because my previous GP had not listed any reasons for stopping the first trial! Whoever said ezetrol has no side effects is deluding themself. It is bad enough with the listed 'common' side effects but when you get on to the uncommon as I did, it is aweful! It makes statins look innocent! I'm still not sure whether there is any evidence of its working??? Good luck with it-you may be one of the lucky ones.

Richbod

maisie_dazy profile image
maisie_dazy

I have had severe problems with both statins and ezetimibe (ezetrol) and discontinued them last year. For years I was telling my consultant how they were affecting me but I was told it was "all in my head" and that I shouldn't keep reading the medication leaflets. Now I am seeing a different consultant who restarted me on the ezetimibe alone and if all ok with that would put me on a low dose statins therapy (5mg crestor twice a week) however after only one ezetimibe tablet I was back to square one experiencing the most awful joint pains. After reporting this I have been told they didn't feel it safe for me to restart them or a statin. I have now been prescribed a fibrate and have started that today. Not sure how that's going to go but I will give it a try. Like Richbod said you may be one of the lucky ones that get no problems. Let us know how you get on...all the best

Maisie

Richbod profile image
Richbod

Good luck Maisie. Hope it works out for you. Let us know.

Richbod

Googol profile image
Googol

I take 10mg Rosuvastatin and 10mg of Ezetrol a day and have not have any side effects. My consultant says I am a high absorber. I have FH and at the start of my treatment my cholesterol level was 19mmol. Rosuvastatin was the second statin I tried and this brought my level down to 10.7mmol after over a year on the statin. So my consultant put me on ezetrol and after 2 months my levels dropped to 7.9mmol. I'm very happy with this.

After reading the literature about Ezetrol I raised my concerns with my consultant and he explained this to me:

* For people whose high cholesterol is because of diet alone (and the levels not so high) Ezetrol will have no effect.

* For people with FH but are not a high absorber ezetrol may only have a little effect.

* For people like me, whose liver when confronted by a statin, click on another process to make/keep cholesterol, ezetrol is essential as it's this second process that it's having the impact on.

Most people do not start this second process (sorry bit short of details to what this is) so ezetrol has no impact.

I realise that there's a possibility that my artery walls thicken on ezetrol which may mean a heart attack is more likely but In my case my cholesterol is so high that without ezetrol my lifespan is shortened considerably anyway. I prefer getting my cholesterol down to an acceptable level and as you can see there's a way to go yet.

Aliwally profile image
Aliwally

In answer to Maisie's consultant, sorry to be so sarcastic but isn't the patient information there to give information to patients!

Perhaps he would like to return to the days when packets had "The Tablets" on them and nothing else, does anyone else remember that.

jillgloucester profile image
jillgloucester

Thank you everyone,,,, really all interesting and Im starting to understand things alot more....

rogerdutton profile image
rogerdutton

Hi all,

My experience is of taking a variety of statins at what is regarded as a starting dose, after a while of being told the memory problems were due to age, I did a little research. difficult to be sure how valid the research is, but with a cholesterol very little above the normal for my age ,without meds I came of statins and on to ezetimebe. Happier now without the memory problems that may have been caused by say stress or age or statins or whatever.

Interestingly a contributory factor to my TIA stroke may have been sleep apnoea, not too severe but enough to affect my work. No cross referal from stroke to sleep despite the consultant saying 'sleep apnoea commonly gets worse after a stroke TIA or otherwise. WHY, well lack of resources and joined up thinking. Deppression so likely after such an event and my disturbed sleep patterns seem to support the 'Human Givens' approach which lifted MY deppression quickly when I got treatment for the sleep apnoea (CPAP).

Had t5o use all my experience of Yoga to prsist with wearing the apnoea mask all night but am now working again and out of the worst of the deppression. Familial factors rule , not overweight or a smoker.

Hope these jottings help Rogerd TIA 2008 sleep apnoea treated 2010.