Last week I had a local anaesthetic at my new dentist, I presume lidocaine. I am pretty sure I wasn't asked about liver disease in the registration medical questionnaire but just saw an academic research paper about lidocaine toxicity with cirrhosis and am now a little concerned. I am well compensated although my recent ALT was elevated at 60 which I need to speak to my consultant about in 2 weeks time. Has anyone else heard about this contraindication ?
Thanks - Pete
Hi I have not heard of that .
Hi Pete, I haven't heard about this for topical (oral) use. The current guidelines for hepatic impairment are based around iv infusion so a local anesthetic with lidocaine (or usually lignocaine these days) shouldn't cause you any issues as a one off. Academic papers make great reading but probably best to stay away If they make you anxious. Hope this makes you feel a bit better ☺️
Thanks for that Katt I appreciate it - as a former (albeit non-scientific) uni academic, research reports don't make me anxious per se but I see your point. I read on UK site that lidocaine was the most commonly used local anaesthetic injection in UK dentistry - the report was a BMJ single case of lidocaine toxicity in a 60 year old with cirrhosis. The application was topical (gel and gargle). I've been OK and I am sure as you say probíably nothi g ti worry about. I will check it out with my consultant when I next see him.
No worries ☺️Nice to meet someone else who reads papers that isn't in the field! I find it all so fascinating. Plus it makes for great conversation, lol x
I had full on sinus surgery using lidocaine in abundance when I had cirrhosis without issue. It’s usually done under general anaesthetic but they said that would have probably killed me.
Cholecystitis and Cirrhosis
decompensated cirrhosis?
PSC and Cirrhosis, Diet
Cirrhosis or not cirrhosis?
