Is it safe to take an antidepressant (Duloxetine or Cymbalta) with liver disease?

[Odie81]

Hi Everyone. Due to my pain, anxiety, and neuropathy, my doctor suggested taking Duloxetine. I read online that you should not take it with liver disease. I already take Lyrica. Any thoughts or suggestions regarding taking it or other safer drugs?? Thanks for your input.

[AyrshireK]

It wouldn't be advisable for any one here to offer any advise on safety of any medications. You should discuss this more fully with your doctor - especially in the light of you not yet having a full diagnosis yet.

[Odie81 in reply to AyrshireK]

Ok. Thank you. Just wondered if others were taking it or what were some other options. Sorry for the post.

[AyrshireK in reply to Odie81]

No need to apologise, it's just that we can't advise and even if people are in a similar boat it doesn't mean what they take is safe for you. Most medications have a label about them not being safe for the liver or to check with your doctor to take if you have a liver condition. Your doctor (with your full medical history to hand) is the only person who should advise you on what is right for you.

Katie

[Odie81 in reply to AyrshireK]

Ok. Thanks again. Truly appreciate you and this site.

[Beachgirl77]

I take Cymbalta and have liver disease. I have been taking Cymbalta for decades, it was prescribed to help my fibromyalgia. It did help and also helped my depression. I have been on it ever since as it is very hard to stop and at my advanced age I probably won’t even try. My fatty liver was diagnosed about 4 yrs ago and is now progressed and I have hardening of the liver. I go for another fibroscan in two weeks so we’ll see if my dietary changes have helped.In answer to your question, the specialists I have seen never suggested going off of Cymbalta. Hope this info helps.

[Odie81 in reply to Beachgirl77]

Thank you for your reply. I hope you get good news from your doc.

[pushthrough]

I take Wellbutrin but have taken cymbalta for 2 years. I have to say it was the hardest ssri to get off to date. However it did help me. I wish you the best.

[Odie81 in reply to pushthrough]

Thank you so much!