Urso side effect: Hi all! I taking urso... - British Liver Trust

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Urso side effect

Belgium22 profile image
10 Replies

Hi all! I taking urso for 2 month and since a day one my stomach is bloated and full of gas every evening. It even strats always in the same time! My next appointment with the doctor still far away and this side effect really affects my life.

Is anybody else has the same problem? How to deal with that?

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Belgium22
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10 Replies
Wass71 profile image
Wass71

Hi,

I couldn't tolerate urso, they tried different dosages etc but it gave me terrible stomach symptoms. Mainly diarrhea, lower abdo pain. It is very important to continue taking it if its having an effect. In my case my alk phos was still climbing despite persevering for a number of months. Some say those symptoms improve over time. Without having any medication my PBC has caused cirrhosis and I'm now on the transplant list. (in the UK you go on the TP list at the point you need a liver ASAP).

So if you are in the early stages and you bloods are being controlled I'd try and stick with it for as long as possible. Maybe take the meds at a different time of day, or split the dose up. Talk to your Dr's about that first though.

Hope it improves for you,

Best wishes

XWassX

Belgium22 profile image
Belgium22 in reply to Wass71

Thanks

Huggy7614 profile image
Huggy7614

Hi,

Wass is right. When I first had Urso I split it into 3 times a day, and after a year my consultant said I could then take it once a day. I must say I never had any side effects from taking it and was on it for 2.5 years until transplant. I was initially unresponsive to it, but later became responsive. Good luck with it and persevere.

Andy.

Belgium22 profile image
Belgium22 in reply to Huggy7614

Thanks

AndyEssex profile image
AndyEssex

Can I ask if Urso is Ursodoxycholic Acid?

Belgium22 profile image
Belgium22 in reply to AndyEssex

Yes.

AndyEssex profile image
AndyEssex in reply to Belgium22

I've been taking that for 18 months and my stomach doesn't feel bloated but I do look as though I have a middle age spread now lol.

I guess that might be from the transplant and the 2 hernia operations.

When you say "gas", do you mean you have to parp it out on a regular basis?

Belgium22 profile image
Belgium22 in reply to AndyEssex

Yes, that is what i meant.Lol)

Thanks for your reply🌸

Good Afternoon Belgium22,

It is not unusual when first starting Urso (Ursodeoxycholic Acid) to have some gastro upset.

You would be best placed discussing this with your medical team but as our forum members have said , sometimes taking the dose at different times of the day can help hugely.

I have included a link to the British Liver Trust information on PBC which you may find useful.

britishlivertrust.org.uk/li...

Again, do not make any changes to your meidicnes until you have discussed it with your medical team .

Best wishes

Trust9

Belgium22 profile image
Belgium22 in reply to

Thank you🌸

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