Hepatic necrosis and acute liver failure - British Liver Trust

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Hepatic necrosis and acute liver failure

Jamielee33 profile image
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I recently discovered after 12 years my mum passed due to hepatic necrosis and acute liver failure, I have research it but can't find a cause and description of what these are, could you help me understand?

All it states is it could be cause by excessive alcohol consumption or paracetamol overdose, is this correct?

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Jamielee33
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Hepatic necrosis: Dr Google says: The clinical course of acute hepatic necrosis resembles an acute, toxic injury to the liver with sudden and precipitous onset, marked elevations in serum aminotransferase levels, and early signs of hepatic (or other organ) dysfunction or failure despite minimal or no jaundice.

I can only guess (as I'm not qualified) that the toxic injury could be related to a possible drug induced liver injury. Dr Google again says: Toxic liver disease with hepatitis. Toxic liver disease with cholestasis. Hepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage. Drug-induced liver injury is a cause of acute and chronic liver disease.

Hope this helps. I know that sometimes the actual cause of death can be rather confusing. In my own Father's case he died of alcohol-related liver disease, but in the later stages his liver could no longer help the immune system to fight off infection so they recorded his cause of death as being pneumonia. Which I think is rather misleading when it really was liver failure.

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