Hepatic necrosis and acute liver failure - British Liver Trust

British Liver Trust

36,527 members17,971 posts

Hepatic necrosis and acute liver failure

Jamielee33 profile image
1 Reply

I recently discovered after 12 years my mum passed due to hepatic necrosis and acute liver failure, I have research it but can't find a cause and description of what these are, could you help me understand?

All it states is it could be cause by excessive alcohol consumption or paracetamol overdose, is this correct?

Written by
Jamielee33 profile image
Jamielee33
To view profiles and participate in discussions please or .
Read more about...
1 Reply

Hepatic necrosis: Dr Google says: The clinical course of acute hepatic necrosis resembles an acute, toxic injury to the liver with sudden and precipitous onset, marked elevations in serum aminotransferase levels, and early signs of hepatic (or other organ) dysfunction or failure despite minimal or no jaundice.

I can only guess (as I'm not qualified) that the toxic injury could be related to a possible drug induced liver injury. Dr Google again says: Toxic liver disease with hepatitis. Toxic liver disease with cholestasis. Hepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage. Drug-induced liver injury is a cause of acute and chronic liver disease.

Hope this helps. I know that sometimes the actual cause of death can be rather confusing. In my own Father's case he died of alcohol-related liver disease, but in the later stages his liver could no longer help the immune system to fight off infection so they recorded his cause of death as being pneumonia. Which I think is rather misleading when it really was liver failure.

You may also like...

Mum in hospital.. Acute alcoholic hepatitis and failing kidneys

having a difficult time, my mum has been in hospital for 10 days, went in due to complications with...

Some hope with liver failure

Hi my Dad has been in hospital with liver failure and pneumonia for five weeks. He has acites and...

prognosis for liver failure?

colleague and old mate is in Hospital with liver failure-through drink. its an old story-he's had...

Undiagnosed liver failure

from Bulgaria...I have some kind of subacute liver failure that cannot be diagnosed because of...

hepatitis B with chronic liver disease

diagnosed hepatitis B with chronic liver disease and now i am waiting in early appointment for...