My husband was diagnosed with HE last November (he has decompensated cirrhosis) and was prescribed Lactulose. It has not been effective and his specialist has now given him a private prescription for the antibiotic Rifaximin. We took it to the chemist who have to order it in and it will cost in excess of £100 per week. We have been to our GP to see if we can get it prescribed on the NHS and she is waiting for a reply from the manufacturer. Anyone else bumped into this? Any thoughts or suggestions would be much appreciated please.