Some drugs not weight based

[SpaghettiIsGood]

I got the idea for this because I had just read about two people on here who got violently ill from taking a bone med injection.

Some drugs that are not weight based, like flu and covid vaccines, which are made for overweight people as well as thin people. Or, one could think of it as made for a man, as it's always recommended that a man can have more of something safely, like alcohol.

I know a drug I take for r.a. is not weight based. That means I'm getting the same dose that a 300 pound person gets? How can that be? At least aspirin is weight based, sort of, as they have age recommendations on the bottle.

[Fruitandnutcase]

I hadn’t thought of that before - when you think of it I suppose a tiny little elderly lady is prescribed the same amount of bisphosphonate as someone young or an adult man.Maybe someone who knows will tell us more 🤔

[SpaghettiIsGood in reply to Fruitandnutcase]

The men I know who get the flu vaccine don't have side effects. The women I know get sick from it.

[Met00 in reply to SpaghettiIsGood]

That would make a very interesting study, not just for flu vaccine, but Covid vaccine and a whole range of medications. Having said that, I had side effects from my Covid vaccines, but have been fine with the flu one.

[Fruitandnutcase in reply to Met00]

I was fine for all three covid vaccines and my flu one. My husband felt a bit off colour with his covid ones - can’t remember what he said about the flu one - I was fine with the flu one. There’s a lot more of him than there is of me too.It would make an interesting study though. Why are some med doses decided by weight and not others?

Just been looking at weight based dosing of medications. It seems to be common in babies and young children but not in adults with the result that obese adults may be getting too little medicine and severely underweight adults may be getting an overdose.

This paper has more about it and it looks like it has a lost of drugs that are prescribed by body weight

ncbi.nlm.nih.gov/pmc/articl...

[SpaghettiIsGood in reply to Met00]

I had little side effects from j&j vax, but did with flu vax.

Good link you posted, very informative and supported by around fifty studies.

[SpaghettiIsGood in reply to Met00]

Well there goes my vaccine theory, unless you're an exception.

[Met00 in reply to SpaghettiIsGood]

But my husband didn't react to any of them, so your theory still stands.

[SpaghettiIsGood in reply to Met00]

Thank you for that!

[MollyStark]

It's a good point. My husband occasionally takes a sleeping tablet and wakes up feeling fine and refreshed in the morning.

My sister was prescribed the same sleeping tablets once. She is tiny, a very small build. She said she was asleep all night and most of the next day. When she finally managed to get up she felt heavily drugged and it scared her!

[NJBINNN]

I had a bad reaction to my first Zolendronic acid infusion last year and OP problems since. I am underweight (43Kilo) and don’t know if this was taken into account. I am vey reluctant to have another.

[M3745]

I have been asking the same question for years. I am a small person and get more side effects from medications. My dermatologist is the only one who recognizes this. There is a medication that she prescribes for my cystic acne that I am the only one she prescribes 50mg where most of her patients are overweight and they get the standard dosage of 100mg. She said 100mg would be too much for me because it is a potassium sparing drug and that could be dangerous for me. So if an over the counter medication calls for 1 or 2 pills, I always start with the 1. I took a nighttime cold medication the other night and felt so lethargic and awful the whole next day. They do go by weight for animals so why not humans.

[AnnieW55]

Not medication but: Calcium, can a 50kg body really process the same maximum amount of calcium, said to be 500mg, at one time as say a 100kg body? When I was given Adcal the calcium part was 600mg and I was supposed to take two a day - that was with no regard for my dietary calcium.

[Jubux]

I was recently shown a syringe for use in medication for dogs. Rather than measurements in cc, the marks up the side were per kg of dog!