I have been taking Az for some time now - 250mgs each day/or every other day. There has been much written in the techical papers both for an against regular dosing. The "Fors" advise that it does have measurable benefits in reducing the number of exacerbations in cases of severe and very severe COPD. The "Againsts" advise that it both has the potential of increasing the resistance of bugs to the treatment by antibiotics and further that in some minor cases it leads to hearing loss (but which appears to return to normal once the drug is discontinued). The reason I take it is because my FEV1 is between 17-25% and cannot afford to lose anymore lung fuction which typically accompanies an exacrbation. Recent reports have a typical exacerbation reducing lung function by around 3% - a rate I cannot afford to lose! Whilst AZ is not cheap the alternatives (losing lung fuction and potentially spending time in hospital) are not attractive. Obviously the choice is up to the individual. Take care
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