British Lung Foundation
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Difference between inhalers ?

Hi All, I do hope you are all doing well and able to breath!!

I am wondering if anyone could tell me the difference between Spiolto Respimat and Stiolto Respimat...both are inhalers, prescribed for people with COPD...severe in my case!! I have been taking the new Spiriva Respimat which has been amazing, but this new one...I have yet to try it. Just wondering if anyone out there has any knowledge on this. I do hope so. If so how are you finding it...especially Spiolto Respimat?

wishing you and yours all the very best now and in the future. May the universe shine on you. Many thanks in anticipation!

Jules aka Juliette011

21 Replies

Hi Juliette, I, too, have been prescribed Stiolto or spiolto Respimat & I'm given to believe that they are one & the same. I live in th U.S. & it's called Stiolto but manufacture in the UK where it's called spiolto - go figure! I like it because it's a mist & does not contain steroids. To date, this is all the info I have - if you find out anything new please let us know. Stay well & stay in touch!


Thank you so much for your information. I really appreciate it. And yes of course I will let you know when I find out more info. Cheerio for now.


Thank you Putsywillow1, I am still trying to assess if I am on the right inhaler now...the Spiolto...I think it is much better and maybe I am aiming for perfection, but have read a few worrying things about it!! But those 'things' could be said of the spiriva and seretide. Where you using those before trying the stiolto??

I think my mind says were on three puffas, ventolin, spiriva, seretide and now only on ventolin and spiolto...(and heres the funny bit) three must be better than just two!!!

Also I was on the others for some years, so I figure it will take time to really know.

Just curious as too how you are going....also do you use oxygen therapy too??

If you don't wish to disclose anything I fully understand.

Whatever the case I hope you are travelling well and all is good with you and yours in your orbit. You too please stay in touch...You made me feel really welcomed. Thank You.


Hello Juliette,In response to your latest inquiry, all is well(as can be expected) with nothing new to report. But to answer your question, no I am not on oxygen. I'm still new to all this as I was only definitively diagnosed with copd - stage 2 emphysema in January of this year! I'm 75 yrs & I just recently completed a 36 session in pulmonary rehab. I exercise, do the breathing exercises, etc. in the attempt to slow the progression of this disease - I guess that's all one can do! How are you doing with the Stiolto? Be well & stay in touch.

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"Ingelheim, Germany, 2nd July, 2015 — Boehringer Ingelheim today announced regulatory authority approvals for Spiolto® Respimat® (tiotropium/olodaterol) in first European countries†. Spiolto® Respimat® is a once-daily maintenance treatment to relieve symptoms in adult patients with chronic obstructive pulmonary disease (COPD). Approvals of the treatment in other European countries are expected to follow in the coming months. Spiolto® Respimat® provides significant improvements in lung function, breathlessness, quality of life and rescue medication use over Spiriva® right from the initial stages when patients need maintenance therapy.1 These additional benefits could enable patients to remain active and avoid the downward spiral of COPD for as long as possible."

Registered as Stiolto™ Respimat® in the US

Marketed as Striverdi® Respimat®


Thank You so much for your information....It all helps. After reading all your replies I now can't wait to try it.


Dear PMRPete, Thank you for the info on Stiolto/Spiolto - mystery solved!

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Good morning julie.i was diagnosed with COPD EMPHYSEMA last week and I'm now on 3 inhalers below I've included the ones I'm on at the moment I really hope it helps you. The very last 2 apparently are I think one and the same


In terms of medicine, Ventolin and Salbutamol are exactly the same.

They each contain the same concentration of medication and they each have a capacity of 200 sprays, with 100 micrograms of Salbutamol in each spray


What is it used for?


Fostair inhaler is used to treat people whose asthma is not controlled with regular corticosteroids and as needed short-acting bronchodilators (relievers, eg salbutamol). As it is a single inhaler, it can also simplify treatment for people who are already using both a corticosteroid inhaler and a long-acting bronchodilator inhaler.fostair can be used in one of two ways in the treatment of asthma. It can be taken regularly to prevent asthma attacks (maintenance therapy), with a separate reliever inhaler (eg salbutamol) used to relieve asthma attacks. Alternatively, it can be used regularly to prevent asthma attacks AND used as a reliever when needed to relieve asthma attacks (maintenance and reliever therapy).

Chronic obstructive pulmonary disease (COPD).

Fostair inhaler is used for people with severe COPD who have repeated attacks of breathlessness, despite regular use of long-acting bronchodilators such as formoterol or salmeterol.


We know COPD makes it hard to catch your breath. That's why STIOLTO RESPIMAT tiotropium bromide and olodaterol) is available in the STIOLTO RESPIMAT inhaler. It delivers the 2 medicines you need in a slow-moving mist to help you inhale it. Without chemical propellants, powders, or steroids. 2 puffs, once a day, can help improve your breathing all day and night. As with all medicines, take STIOLTO only as prescribed by your doctor.

Spiolto® Respimat® approved in first European countries - Boehringer Ingelheim

Spiolto® Respimat® is built on tiotropium, the active ingredient in Spiriva®, enhanced by olodaterol Spiolto® ... As of Monday 29th June, Spiolto ® Respimat ® has been approved in Croatia, United Kingdom, Slovakia, ...

Best wishes

God bless



Thank you Ian for all your informative info!! Yes now I can't wait to try it, but fear the change a little...coz the Spirva respimat with the fine mist is fantastic (and apparently this new one will be the same mechanism) and the Seritide has been really powerful. I have my ventolin first, try and wait five minutes, then the spiriva respimat and then seritide...2puffs morning and night...the night one seems to help me when I rise in the morning...But this new lot apparently has both and I am to cease the Seritide. I do so appreciate all your information. So I now understand that Spiolto and Stioloto are one and the same...Yes?? thank you again.


I have been on the Spiriva handi haler (the pill with the powder in it) for several years. I also have very severe copd. When I went to the doctor for my annual checkup in June, my doctor put me on the Stiolto Respimat. Spiriva has only one medication in it, tiotropium bromide, which works to relax airways. Stiolto has 2 medications, tiotropium bromide AND olodaterol, to both RELAX and OPEN airways. My ability to breathe is pretty bad, but the Stiolto is giving me more ease than the Spiriva did. Here is a good link to read to compare the two:


Nikilet, can I ask whilst you were using the Spiriva inhaler did you experience a dry mouth?


Well yes and know...but the new Spiriva Respimat which I still use until I start the new Spiolto in my opinion is amazing, far superior than the spiriva in the powder capsual form.....but I am also on blood pressure medication and that could also dry out my mouth. Sorry I couldn't be more helpful.


Yes. I suffer with dry mouth. But you can buy products to help with that. For instance TheraBreath Dentist Formulated Dry Mouth Lozenges, Sugar Free. I purchase these on I also use TheraBreath Dentist Formulated Fresh Breath Oral Rinse in the green bottle.

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Thanks Nikilet, will have a look for them.


That really good news I have really bad trouble with my breathing. Mornings and night is just awful I am on spiriva I'm going to ask my matron if she can get it changed


We are all different and react differently to inhalers. Spiolto Respimat had a very bad effect on me - Spiriva replaced it and was brilliant. Seretide was good but Fostair is far more versatile; Spiriva has now been replaced by Braltus which is useless in my case - has anyone else used it? It is just tiotropium.


Hi There Dragonmum (and I bet you are not!!)

I am still trying to assess if I am now on the right inhaler...The is working, but?? I still can't really be sure...although I am breathing better to a degree...not by that much. You would know that it has tiotroplum and olodaterol.

My question to you is The you use that with ventolin? and what was happening to you when using the say it had a bad effect. So if you don't mind sharing I would be interested to know...if not I fully understand. I've not heard of either the fostair and braltus!! all very new to me.

Bottom line whatever you are using now I do hope it is working for you and all is well in your orbit!!

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If it's spiolto respimat I persevered for almost two weeks (won't do that again) and quit when I was propped up with 4 pillows and still gasping, no hope of sleeping. This was replaced by Spiriva which was excellent, but cost-cutting means that the replacement of this with Braltus, which I found to be on a par with spiolto and will not take, has left me with no preventor. Fostair is quite brilliant and very versatile and yes, it is prescribed alongside the short-term Ventolin reliever which I use very infrequently. So I now have a steroid reliever, Fostair, plus Ventolin for short term relief. Let me stress here that if I've learned anything on HU it is that we all respond differently to different products - there is no one-size-fits-all solution.

I was diagnosed with asthma in 2002 then a new practice treated me for COPD though I've never had so much as a chest X-ray let alone seen a counsultant, maybe they have a crystal ball? If Spiolto is working for you then stick with it Juliette - I have had so many different good inhalers, Seretide, Atrovent worked well for years but cost-cutting ruled these out a few years back. In Wales we have free prescriptions, unfortunately that, in my opinion, leads to the prescribing of "affordable" treatments.

I hope this answers your questions and please dig your heels in if you find you are having problems. I wish you the best of luck in finding your way through the maze!!!

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Many thanks Dragonmum for all your insights. Of course I know we all react differently. I am about to put up another post, coz I'm still not too sure about this spiolto ... stiolto to you!! feel like I'm swearing with these two names, LOL. take honey bunny and look after self.


To be honest, I was told I had advanced copd 8 years ago. At first my doctor gave me a couple of different inhalers as samples. I tried using them but couldn't feel any improve- ment from either brand. after a while, I moved to where I live now and have yet to have a doctor here even mention one. To be honest with you, i don't think most doctors know what to give you for copd. All the meds i do which come from nebulizer use do not seem to give me any help at all. They are very expensive but the results don't make me breathe any bet ter.


What I have noticed with my new inhaler where my other one are powder based where Spiolto Respimat is a fine mist so it feels like nothing gone in but it does


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