I have shortness of breath which may be angina and I’m having tests done on my heart. As I also have mild anxiety I take an antidepressant. I’ve noticed that after changing brands my shortness of breath got worse. I tried a brand I’d had before and my breathing improved. I know that different brands use different fillers and I’m wondering if this is why I suffered when I changed the brand of my bisoprolol? I’d got over the initial side effects of it when the hospital lowered my dose and gave me a different brand which gave me terrible side effects so I stopped taking them, with my GP’s agreement. I do suffer awful side effects when taking medication and have just realised that I just need to try different brands instead of giving up. Anyone else who suffers side effects like me, just try a different brand before stopping first.