Diabetes Remission Clinical Trial (DiRECT)

[Milkfairy]

"The research revealed that the proportion of participants in the extension of the landmark Diabetes UK-funded Diabetes Remission Clinical Trial (DiRECT) remission after five years was more than three times that of the DiRECT control group, who did not take part in the original low-calorie diet programme or receive continued low-intensity weight management support in the extension trial."

ncl.ac.uk/press/articles/la...

diabetes.org.uk/about_us/ne...

[Chappychap]

Thank you for this very relevant post.

Relevant because my GP reckons that about a third of patients with heart disease/atherosclerosis have it due to an underlying drift towards T2 Diabetes, but in many cases their HbA1c scores haven't yet reached the trigger point where they'll be formally diagnosed.

So the irony is that many of us on this forum know about our atherosclerosis, but we're clueless about the insulin resistance or pre-diabetes that caused our problem in the first place, and without intervention will keep making our heart problems worse.

The first tragedy is that for many people simple life style changes would drive their HbA1c scores back down, and even (as Milk Fairy's research so clearly shows) put full blown T2D into remission.

The second tragedy is that modern diets, full of highly processed foods and constant snacking, are likely to be at least one factor, if not the key factor, in Britain's steady march towards obesity. We're the fattest country in Europe, and we just keep getting fatter still. Now that so many people have quit smoking, being overweight is the number one factor driving up T2Diabetes, heart disease, and many forms of cancer.

And "overweight" rather than "obese" is all it takes.

I'd encourage everyone on this forum who has an annual Cardio blood test to inspect their HbA1c scores. No matter what the number, if they are trending up and you are over your target BMI, then losing weight can make a real difference to your future health and life expectancy.

[Kristin1812 Heart Star]

This is really interesting, thank you for posting. My results from the on-line pre-diabetes programme were similar. I lost 10k, have less angina, and blood sugar reduced.