Hi all , has anyone heard of cavadextrin or cavadex , it's an Australian company whose owner had blocked arteries, high cholesterol etc and he claims that a beta cyclodextrin he has developed has reversed ( to a degree ) his atherosclerosis, and dramatically lowered his cholesterol just wondering if anyone has tried it or knows of any reviews , it's available as an injection or via enema and on the market now Tia
Cavadex : Hi all , has anyone heard of... - British Heart Fou...
Cavadex
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The company is called cholrem btw
I have just finished my first month of a three month treatment of Cavadex. My husbands cardiologist suggested this as an additional treatment for his blockages and I decided to try the protocol myself. While I don’t know for sure if it is helping me clear the blockages, I am finding relief with symptoms such as jaw pain.
I am awaiting a new procedure at HenryFord Hospital, a drug eluding balloon procedure, to treat my many blockages. It is finishing up the trial stages and hopefully will be available in the next 6 months. I am also on Repatha.
Heartfixer.com will take you to the cardiologist’s website. He has reported his findings and his journey with the Cavadex treatment. The dr. is taking Cavadex himself and has a group of patients he is currently following. Only positive reviews so far. I have nothing negative to say either, so I am heading into month two with an optimistic state of mind and a confident feeling that I’m doing the right thing for me.
Thanks for that , pls let me know how you get on with the cavadex , and good luck with everything!
What new approach are you speaking about ... we all want to find help
I saw your reply on Health Unlocked about Cavadex (REMCHOL). That was 9 months ago. So how did it go. Did it do anything positive or negative?
Dear Yelllowtracker, It has been over 10 months since you started Cavadex. Have you had a new calcium score to compare to your old calcium score so you can definitively state that cholesterol has been removed from your system? Or not?
Hope you do well and thank you for informing us. I would like to try it myself since I suffered a S TROKE FROM GLOG ARTERIES LAST JULY. I take statins and can not stand the side effects of it. I would like to make sure I do the right thing with cadavex and I dream of getting my arteries unclogged.
Buena suerte, hope this treatment is the real solution to cure clog arteries. I have clog arteries myself and am recovering from a stroke. I want to try CAVADEX to at least prevent an other stroke. However, I AM M RESEARCHING ABOUT IT JUST TO MAKE SURE IT IS GOING TO HELP ME GET BETTER, WISH THE BEST FOR ALL WHO ARE TRYING CAVADEX,
You claimed your husband's cardiologist approved using cavadex. No cardiologist will approve using non-conventional therapies outside the normal field of medicine. You also provided the website heartfixer.com by Dr James Roberts. The website looked like a cheap put together and is not a professional website. These certainly raised some red flags.
There is no way for any medical innovation to occur ( in US at least) based on restriction$ in place in a handshake deals between insurance and pharma partners ( my opinion). Cyclodextrins are regarded safe by the FDA, but cholrem can't make any claims about the benefit from it. Ok fine. Why so protective? There is huge chasm between medical research and clinical practice that seems to get bridged only when someone can make a buck off it. Lately, differentiation of buoyant and remnant Cholesterol (components of LDL ) show the latter to be more harmful.
From my understanding, statins slow progression of Atherosclerotisis (when LDL > 50), but reverse cholesterol transport from cyclodextrin or Trodusquemine reduces existing deposits.
Genaera Corp was dissolved during a trial of Trodusquemine for metabolic disease.
Ref: Reverse cholesterol transport: pubmed.ncbi.nlm.nih.gov/270...
Ref: Remnant cholesterol
ncbi.nlm.nih.gov/pmc/articl...
Ref Dr Lustig ( neuroendocrinologist) youtu.be/zG4XD116uy8
LDL awareness alone is not enough. uclahealth.org/news/release...
Trodusquemine research company is a dissolved during trials: fiercebiotech.com/biotech/g...
sec.gov/Archives/edgar/data...
"... looking for evidence supporting our pre-clinical observations that trodusquemine induces appetite suppression and weight loss while normalizing glucose metabolism and insulin sensitivity.”
Cyclodextrin Generally regarded as safe:
ncbi.nlm.nih.gov/pmc/articl...
Fact checking welcome. Yeah... Am a little obsessed. Recent crash course in sugar and lipid tech trends.
Btw, why are blockbuster drugs defined by financial performance?
Hi, I was wondering how you were getting along and your thoughts about the Cavadex treatment.
After a bit of digging, I found information about the owner of Cholrem, Kyle Hodgetts: alert947.rssing.com/chan-58...
An Australian news outlet did a story on him in the 2010s. crikey.com.au/2017/08/31/vi...
The opinion of both the NHS and the BHF (who sponsor this forum) is that atherosclerosis is both incurable and progressive, ie we've got it for life and left to its own devices it will just keep getting worse. Both authorities say there is no way of reversing the condition, and that stents and even bypass surgery are not a permanent fix.
On a more cheerful note, they do say however that an optimised programme of medication and life style changes can, for some people of least, slow the progress of atherosclerosis. In the best of cases medication and life style changes can delay the disease to an absolute crawl, adding decades of healthy active years to our lives.
Rather than investing hope and cash in some internet quackery, we're better off knuckling down and doing the hard stuff; like losing weight, quitting smoking, eating healthily, drinking moderately, and exercising regularly.
I've knuckled down and done all that to no avail, things keep on getting worse so I'll keep looking at potential breakthrough treatments as one of them may come good in time. I suppose statins were 'Internet quackery ' once !
Statins were only available after a meticulous, peer reviewed testing process. They were never internet quackery.
I understand your frustration, and yes there are a small percentage of us with certain deterministic genetic conditions (such as familial hypercholesterolaemia, for which happily there are some effective breakthrough drugs). More significantly there are the 17% of the population that carry the APO E3 gene, which significantly raises susceptibility to fats and alcohol.
For the great majority of us our atherosclerosis can be mitigated by life style changes. In most cases it's the obvious stuff, but for others it may be much more subtle life style issues.
For example anything that interrupted sleep is a known life style risk factor, which is why sleep apnea patients and shift workers both suffer elevated heart attack risks. Or there's gum disease, or living with high levels of dust or pollution. The list goes on.
I guess what I'm saying is exploring some of these life style options may be more effective than unsubstantiated cures.
Good luck!
This type of view is exactly why big pharma and doctors kill more people every year than heart disease does.
Reverse cholesterol transport is a thing. Cyclodextrin and Trodusquemine.. pubmed.ncbi.nlm.nih.gov/270...
in the opinion of several NHS doctors it is not possible to have glandular fever more than once - i had it three time, each time with a positive NHS test
i am not suggesting that all NHS doctor (or experts) are wrong, simply that all of them depend on the current state of knowledge and their own preparedness to stay up do date - they did not believe in ischaemia without blocked arteries until it was shown to be possible!
nor i am not advocating the treatment suggested here - but i do urge caution and checking things out as thoroughly as you can
Being an Australian company its unlikely they report their results to UK or USA authorities. Instead of guessing id suggest just contacting Cholrem directly ?
this comment should probably be made to the original poster
I'm not great with computers.
when you want to comment on something make sure you select the "Reply" option at the bottom of the bit you want to reply to, - it can get confusing when there are a whole string of other comments but a quick scroll up to check usually pays off
It's such a shame in the UK that is the main advice, but I have even had a lipids expert say here it is possible to reverse CHD with a LdL reading of 1.5 or less.
In the US theyve been shown to be reversing CHD for decades through nutrition. Look up Dr. Esselstyne or Dr. Ornish.
I reversed cholesterol as measured by calcium scores using Dr. Esselstyne vegan guidelines. However, it is not enough of a reversal for me. I would like to get rid of most of the cholesterol in the arteries.
So you actually reveresed the calcium in your arteries, which is actually even more impressive. The soft plaque is cholesterol yet turned into calcium.
Yes, I reduced it 13% whereas The average change in the calcium score (Agatston method) is about 33.2 +/- 9.2%/year, according to "Rates of progression of coronary calcium by electron beam tomography, found in the NIH library.
As I understand, if you already have a calcium score of hard plaque, that means that you also already have substantial soft plaque. It seems that your calcium score indicates hard plaque at about 20% of Total Plaque, and the remainder 80% is soft plaque. That is why I do not take the invasive CTCA or CCTA or Coronary computated tomography angiography (all the same depending on where you live) with the injection of iodine and dyes plus extra radiation. I can calculate my approximate soft plaque.
Ideally, I want to get rid of the soft plaque since the hard supposedly is the result of the body placing a protective layer over the soft plaque. It is the soft plaque that causes heart attacks in hypothesis, not the hard plaque.
So I have done everything non-invasive. Gone vegan, though now I am adding the FDA three meals of non-mercury omega 3 fish per week. The best fish that meet their criteria are: anchovies, herring, ATLANTIC or PACIFIC mackerel only, PACIFIC oysters, wild ATLANTIC, CHINOOK or COHO salmon (not the farmed or other kind), ATLANTIC or PACIFIC sardines, and FRESH Water US Trout.
Also, the FDA recommends 25+ grams per day of soybean / tofu to reduce coronary heart disease risk.
(I don't have time to do a meal plan, so I stay vegan except for 3 fish meals per week. Without trying, my weight eventually went back to high school weight pretty dramatically around two years of eating Esselstyn vegan. (I do cheat and eat nut butters though so I am not a true follewer of the guidelines.)
Going Esselstyn vegan is not easy. You basically need to say you will do it and clean the kitchen of all meat products. Serum cholesterol should drop. If you are on medication, like a statin, etc, do it with your doctor because you might need to stop statins after you go vegan and stop insulin also, You blood sugars should drop too.
Pretty much agree with all that, although. 'going vegan' - I hear too many people thinking vegan means healthy eating, which isnt necessarily true. You can eat crisps all day and be vegan!
Dr Esselstyne prefers WFPB - Whole Foods Plant Based , i.e. ideally wholegrain rices and pasta, breads etc, lots of veggies and some fruit.
No fat, that includes butter o=f any sort, no added oils, limit salt, limit sugars.
I really dont find it hard to follow but I guess if you're a staunch meat and dairy eater you may do.
I try to do better everyday as I'm not perfect on the diet but I am 90% there at least.
Regarding cleaning out the arteries, we all obviously want to do that, how realistic it is to get a large amount of clearance is really unknown, but I simply put it down to how well I feel.I had crippling stable angina when I started my journey, now I only get angina under intense exercise.
It is so good to hear you feel better, except under intense exercise, and no longer have crippling angina. It's good to feel like you are the CEO of your health and pro-active. Clearly what has been going on since the 1980's and that continues to this day isn't working. I lost my dad to a heart attack, and I don't want my son to lose his parent.
You are so right that WFPB is a healthy vegan. A mate drank beer and ate crisps (french fries for Americans) all day then topped it with a chemical, plastic wrapped grab-n-go snack cake pastry and technically was vegan. He boasted he was vegan. He wanted to lose weight which never happened.
I very much agreed that Esselstyn's guidelines are good to stay close to. I have evolved some. I do add omega 3 fatty fish only (4-6 ounces) 3 times per week like the FDA recommends. I try to adhere to the FDA daily 28 grams of soy or tofu to prevent heart disease. It is easy if you have an old George Foreman Grill. Just slice it and the grill browns it while draining the water out of it. Done in 4 minutes with a meat consistency (dont need to mess with the recipes calling you to prep tofu by squeezing water out and putting in a marinade for hours.) Then top with your healthy salsa (Mexican day) or sauce like vegan steak sauce.
I am also modifying Esselstyne to follow Prof. Rob Lustig (sugar expert who advocates no added sugar at all, but fruit is fine), Dr. , William Davis (advocated calcium score in the 1980's over stents & later wrote Wheat Belly), and protein expert Dr. Don Layman. Humans do not need grains, and in me it causes too much Triglycerides (which in a fasting state is VLDL, that becomes sd-LDL or the deadly LDL). I needed to bring TG under 60 mg/dL (still not there, but at that point you stop adding to plaque) and loosely following Dr. William by cutting out all wheat helped tremendously. He advocates NO grains, but I still eat oatmeal. I cut out all the white and brown rice too and that helped; it has too much arsenic anyway to worry about anyway.
Incidentally, high TG is a 1.8 risk of a heart attack. In contrast, high LDL is only a 1.3 risk of a heart attack, but doctors prescribe statins to reduce while ignoring TG. It seems logical to lower TG first, and what you eat is the only way and a cheap way to lower it. (There are drugs being tested to lower TG's and probably they will become the new statins prescribed to everyone if they are approved.)
The protein expert Layman is great to learn about the new disease called sarcopenia, which is basically old man frail syndrome. He advocates 30 grams protein at your first and last meal of the day. More than 50 grams is a waste in that it doesn't develop muscles, BUT only if you exercise (resistance with weights, sit ups, push ups, pull-ups). After age 40 the stomach and thigh muscles are the first to atrophy. AND Eat that 30 grams protein ONLY IF you first eat 5 vegetables the size of your fist and two fruits with three optional grains. Use your hand, open it up and that's how many vegetables you need to eat DAILY (assuming you have 5 digits), close and make a fist and that is the size you should eat. I need to keep it simple to remember.
As to CholRem, I do not trust the Australian product without a certification of sanitation or purity that is obscenely expensive for a common unpatentable product that is delivered in a very common (though possibly messy) manner without needles. It does seem to be the perfect DIY product. I am game to clear out the plaque built up over the decades and will research further. Might even join the FB, but probably not.
Dear Jazza, what is the name of your group? Have you consider putting it in a more secure location that doesn't sell your information, your profile, and what you write?
I agree with a lot of what you say, although I tend to think we should be eating as we did for milennia as cavemen and women, from the ground, the bushes and trees with the occasional kill, possibly because of winter.
The problem is our food is now so full of pesticides and who knows else what, its v hard to eat naturally.
Whilst I agree that a high TG is the enemy, I defintely don't think oats/grains etc are to blame.
Sugar is THE processed food. We no longer think of sugar as being processed because its been around that long, but sugar in its natural state is cane!
If you eat naturally, and as whole foods as possible your TG and LDL will fall remarkably which is what mine have done.
The kye word here is 'added'. Don't resort to 'added' anything! Sugar, salt, oil. All added to increase flavour. Once you give them up within. a few weeks your palate changes and you no longer need them anyway.
Then procesed food just tastes of salt and sugar!
Professor Dr. Robert Lustig, sugar expert, agrees with you and no added sugar. There are many interviews with him free on-line that you might enjoy, and he adds further to your expressed thoughts.
healthunlocked.com/bhf/post...
This is the British Heart Foundation view on cyclodextrins found under PAD / CAD treatment.
There is a lot of hype on Cavadex. Kyle Hodgetts, the owner of Cavadex, owned a computer game company who sued Channel 9 (Australia) after an interview. Says a lot about the product. You made a great choice no to trust this product.
Not talking on behalf of Kyle Hodgetts or Cavadex, but there is a lot of growing evidence to show that Cyclodextrins (of which Cavadex is comprised) could be the game changer when it comes to managing and reversing atherosclerosis. We have a bunch of users in our FB group (Cyclodextrins, Nattokinase and Cardiovascular Disease) that are reporting positive results (anecdotal and objective) combining their supplement protocols with cyclodextrins. There is also a new company on the block called Cyclaritytx that you may want to have a look at: cyclaritytx.com/our-science/
I looked into the Cavadex hype and chose not to waste any money on the notorious con-artist, but everyone can do what they want with their money I especially did not find the enemas that cause anal cysts to be attractive.
Instead, I invested (or rather saved more money) by starting a LOW STEROL diet. AND the results were phenomenal. Reduced APO b and LDL. However, you have to be extremely motivated and not think that a pill or soup up the anus will cure you.
It eliminates or severely lowers plant and animal sterols, phytosterols and cholesterol. It also limits saturated fat.
The diet cannot consist of any oil, nuts, or grains. Sound familiar? It seems to be a Dr. Esselstyne for no oils, and a Dr. William Davis for no wheat/grain belly (except amaranth). The nuts are high in phytosterols, so they are out (except curiously chestnuts).
So, I can't say I am a vegan because I now eat egg whites, 95% lean ground beef and turkey, and fatty low-mercury fish.
Good luck all! What you put in for mouth is more important than what you stick up your anus!
Probably what was said about penicillin... you cannot assume everything is quackery... hope is eternal. The meds the pharmaceutical put out that charge crazy prices don't do much and definitely do not reverse or fix conditions
With all due respect there ARE treatments that are available and reverse the plaque. I am a US physician and know for sure there are such approaches. The first and foremost is the direct relationship between the LDL level and plaque size. The lower the LDL, the smaller the plaque gets. There was a recent study published in "Cleveland Clinic Journal of Medicine", with documentation of plaque shrinking ( with IVUS) through the use of combined statins and Repatha. THIS IS A PROVEN FACT. There also has been clinical evidence that aged garlic extract can reverse plaque build up. I am not sure Cavadex would do that until we have more information on the large-population data. In a desperate situation with a huge load of plaque, such as diabetic vasculopathy, any measure that could potentially help is plausible though. If I were a desperate patient with relentless plaquing, I would definitely use Cavadex.
Hi DocRy,
I wanted to share with the group and you information from a posting and account were deleted from a FB Group promoted by a member of this group. The posting had a business address that had already been in two separate postings for months on that FB group. I understand that many people were greatly benefitting from the deleted posting and others who have been critical of RemChol are no longer posting information.
The post deleted is reprinted below in part from what I saved because it had invaluable information.
Self experimenters are using Austrlian Remchol. RemChol has not provided third-party proof of formula, purity or sanitation in the manufacturing or repackaging of their chemical. Mike R. has his Remchol package delivered from an illegal company not registered in Australia with a “business address” of a house with a very big garage which gives a clue that the chemical is not high quality ACS, USP, NF, or Food grade. High quality chemical grades have specific storage and distribution requirements and would not come out of a house. So RemChol, absent a COA, might be industrial or a laboratory grade and repackaged in an unknown facility or house. One googled explanation is at laballey.com/pages/chemical...
Both Darren G. via intravenous, and nurse Billie S. via water enema, trust and use the following 2-Hydroxypropyl-Beta-Cyclodextrin made by RND Centre Inc and distributed in 100 gram powder bottles by Amazon amazon.com/gp/product/B00HR...
Larger quantities can be purchased at rndcenterinc.com/search?q=c...
Billie uses the following enema syringe: amazon.com/gp/product/B0C27...
Nurse Billie S. Formula III is summarized as follows: First two weeks, only use a half- dose or 4 grams. Regular dose is 8 grams. 16 grams (sold by RemChol) is excessive and wasted since the average person can only hold 10 ml water in an enema. Two (2) hours before, discontinue eating completely, consider eating less fiber and fats beforehand. (1) hour before, use a saline enema. Then defecate and the cyclodextrin is easier to hold up to six hours with “no blow out.”
Mix 3 teaspoons or mix 10 grams generic 2-hydroxypropyl-beta-cyclodextrine with 10ml slightly warm sterile water in a snack baggie and squish it around until melted, let it sit, it will melt slowly though it may not seem like it. Put it in enema bulb, syringe or bottle and apply. Disinfect the bulb, syringe, or bulb after use. This is the exact same formulation as RemChol in a small plastic tube that many have discontinued to use because they cannot self administer. The sticky chemical can also adhere to the inside the tube and be wasted. The hose and syringe does not have these problems.
Cost discussion: Many people cannot afford the experimental chemical at the price that RemChol charges. Remchol charges $625 USD for 768 grams in 96 tubes with 8 grams each. The same amount from RND Center Inc. would cost $230.32, for a savings of around $395. RemChol charges $225 USD for 240 grams in 32 Tubes for 1 month supply. The same amount would be $71.98 from RND Center Inc. for a savings of around $153.
Question for RemChol experimenters: Why not buy in bulk directly from a reputable company for an even lower price than doing it yourself?
Question for RemChol experimenters: Why not hire a compounder or pharmacy to make the enema or IV in FDA-certified facilities and ship directly to experimenters? Compounders and pharmacies will likely get an even deeper discount.
There are apparently research & procedures which has proved effective.
Poke around Reddit, there are a couple of Ex personal assistants to people who have family names on buildings who have had procedures which undergo 6-8 hour procedures that use drug eluding balloons & vacuum soft plaque out of arteries.
Then there's Trodusquemine, which research stopped due to finding it's "only able to administer via IV... Fitting it's extracted from the liver of sharks as reason to stop seems awfully fishy.
pubchem.ncbi.nlm.nih.gov/co...
bbc.com/news/articles/cerlx...
Interesting opinions.
Neither the FDA nor EMA have approved cyclodextrins for the reduction of cholesterol. The FDA has given cyclodextrins GRAS status - they are (generally recognised as safe) for use as excipients or food additives but that’s all. This means there isn’t the data available to establish safety and effectiveness as cholesterol reducing agents in the eyes of the regulatory agencies. Some animal data shows a reduction in arterial plaques but there’s no evidence this happens in man. If it were a serious treatment there would be clinical studies recorded on clinicaltrials.gov but there aren’t. There’s a single small NIH study of oral alpha cyclodextrins that failed to achieve its primary endpoint.
As someone with a science doctorate who spent many years developing new drugs, the reviews I’d want to see would be the summary basis of approval (SBA) from the FDA and/or the European public assessment report (EPAR) from the EMA. These reports are reviews by the independent agency experts of all the evidence generated to show safety and effectiveness.
If it really works do you think the FDA whose funding c I mes from big pharma would want this approved or analyzed???
There’s no independent evidence to suggest that it actually works or how well it works. This doesn’t mean that it doesn’t work, just that it’s not attractive to either the industry to fund studies or to bodies like the NIH in the US to fund studies. The fact that they don’t suggests that if it does work, current treatments are more effective.
Cyclodextrins cause regression of plaques, let people try it and stop waving your hands around and trying to be everyone's know it all uncle or naggy mum. Bozo.
If you trust the FDA, and claim to be a ‘scientist’ your opinion should be thrown out quickly.
Why?
It just seems that anything that shows signs of a potential treatment for atherosclerosis doesn't get much further in human clinical trials, I understand that mice are different to humans and that the results don't always cross over , what happened to trodusquemine, touted as a game changer ? I have been on different statins for 25 years and the only difference I have made to my cholesterol levels is when I started on pomegranate juice 12 mths ago !I'm 54 and had a triple bypass at 34 yo, these all blocked up again in 2017, 4 stents in the one remaining open artery to improve blood flow and I will need another triple cabg soon do that's the reason I'm looking at these other therapies , I still work in the building trade but not for much longer !
`have you tried a WFPB no oil diet? If not, look up Dr. Esselstyne who has decades of reversing heart disease through diet.
Hi Dominic Haydoe,
I wanted to share with the group and you information from a posting and account that were deleted from a FB Group promoted by a member of this group. The posting had a business address that had already been in two separate postings for months and discussed on that FB group. I understand that many people were greatly benefitting from the deleted posting and others who have been critical of RemChol are no longer posting information.
The post deleted is reprinted below in part from what I saved because it had invaluable information.
Self experimenters are using Austrlian Remchol. RemChol has not provided third-party proof of formula, purity or sanitation in the manufacturing or repackaging of their chemical. Mike R. has his Remchol package delivered from an illegal company not registered in Australia with a “business address” of a house with a very big garage which gives a clue that the chemical is not high quality ACS, USP, NF, or Food grade. High quality chemical grades have specific storage and distribution requirements and would not come out of a house. So RemChol, absent a COA, might be industrial or a laboratory grade and repackaged in an unknown facility or house. One googled explanation is at laballey.com/pages/chemical...
Both Darren G. via intravenous, and nurse Billie S. via water enema, trust and use the following 2-Hydroxypropyl-Beta-Cyclodextrin made by RND Centre Inc and distributed in 100 gram powder bottles by Amazon amazon.com/gp/product/B00HR...
Larger quantities can be purchased at rndcenterinc.com/search?q=c...
Billie uses the following enema syringe: amazon.com/gp/product/B0C27...
Nurse Billie S. Formula III is summarized as follows: First two weeks, only use a half- dose or 4 grams. Regular dose is 8 grams. 16 grams (sold by RemChol) is excessive and wasted since the average person can only hold 10 ml water in an enema. Two (2) hours before, discontinue eating completely, consider eating less fiber and fats beforehand. (1) hour before, use a saline enema. Then defecate and the cyclodextrin is easier to hold up to six hours with “no blow out.”
Mix 3 teaspoons or mix 10 grams generic 2-hydroxypropyl-beta-cyclodextrine with 10ml slightly warm sterile water in a snack baggie and squish it around until melted, let it sit, it will melt slowly though it may not seem like it. Put it in enema bulb, syringe or bottle and apply. Disinfect the bulb, syringe, or bulb after use. This is the exact same formulation as RemChol in a small plastic tube that many have discontinued to use because they cannot self administer. The sticky chemical can also adhere to the inside the tube and be wasted. The hose and syringe does not have these problems.
Cost discussion: Many people cannot afford the experimental chemical at the price that RemChol charges. Remchol charges $625 USD for 768 grams in 96 tubes with 8 grams each. The same amount from RND Center Inc. would cost $230.32, for a savings of around $395. RemChol charges $225 USD for 240 grams in 32 Tubes for 1 month supply. The same amount would be $71.98 from RND Center Inc. for a savings of around $153.
Question for RemChol experimenters: Why not buy in bulk directly from a reputable company for an even lower price than doing it yourself?
Question for RemChol experimenters: Why not hire a compounder or pharmacy to make the enema or IV in FDA-certified facilities and ship directly to experimenters? Compounders and pharmacies will likely get an even deeper discount.
Did Daren G and Billy S have success using there formula? There seems to be a lot of grey area when it comes to cyclodexitrin. Is it a food is it a drug or something in between. I am sure regulations vary greatly Apparently Billie a Daren being health care workers find some foundation of theory to use it. I have ordered it and have prior CT scores and Cholesterol numbers. I will report back in November of progress. If i get data before then as far as Cholesterol numbers i pass that on as well.
Re Cavadex
This is a highly successful natural product that has been proven to have results. It has also been shown to combat arthritis. It is derived from a natural compound and has no known side effects. It was recently almost purchased by an ASX listed pharmaceutical company, but the deal fell through against a backdrop of multiple global bank failures. The ASX company couldn't raise the funds. I suggest you try it. I have heard good things about it.
If you do try it, post here what you thought of it,
Cheers,
patchit
I ordered didn't get my order as I'm in the US and it's ing from Australia... either got lost or who knows..but I'd like to try anything ... you got to try or die
Hi, Did you ever get your order from Australia three months ago? Did you finish using it for at least a month and take a new calcium score. How did it compare to your prior score? Did it reverse your cholesetrol? Or not?
Dear Patchit, What ASX company almost bought Cavadex 10 months ago? Also, can you show us where there are calcium scores of before and after Cavadex that show a significant reduction in cholesterol? Did you try it on yourself or loved family members so you have actual first-hand knowledge that it doesn't harm?
One of my concerns is that there is no third party supervision over the manufacturing of this product. There are sanitary oversights for pharmaceutical products all over the world, yet there is none here provided. This could be a breaking-bad person making the product in a trailer somewhere in the world. Since this product is used in other areas (food and excipients) it would be a no-brainer to provide certification that what is actually being shipped is truly the product Beta-Hydroxypropyl Cyclodextrin (CD). There are a large number of companies that make the powder under certified conditions. We also need certification that the person who puts that powder into a rectal liquid/gel knows what they are doing and are doing so under sanitary conditions.
I just looked it up and there are only 42 "ASX listed pharmaceutical companies," so which one decided not to buy Cholrem?
Re Cavadex
The information below found on the pubmed.ncbi.nlm.nih.gov/272... website appears to somewhat contradict a lot of the above remarks about Cavadex.
Preclinical Reversal of Atherosclerosis by FDA-Approved Compound that Transforms Cholesterol into an Anti-Inflammatory "Prodrug"
Andrew R Mendelsohn 1 2 , James W Larrick 1 2
Affiliations expand
PMID: 27241174 DOI: 10.1089/rej.2016.1849
Abstract
Although atherosclerosis is treatable with lipid-lowering drugs, not all patients respond. Hydroxypropyl-beta-cyclodextrin (CD) is an FDA-approved compound for solubilizing, capturing, and delivering lipophilic drugs in humans. Zimmer et al. report that CD mediates regression of atherosclerotic plaques in two mouse models by solubilizing cholesterol crystals (CCs), and promoting metabolism of CCs into water-soluble 27-hydroxycholesterol, which, in turn, activates anti-inflammatory LXR receptor target genes, promotes active and passive efflux of cholesterol from macrophages, and increases metabolic processing of cholesterol. In effect, CD inverts the role of its cargo, cholesterol, from inflammatory to anti-inflammatory by converting cholesterol into a "prodrug" that when modified to 27-hydroxycholesterol reduces atherosclerosis. This mechanism defines a new class of pharmaceuticals, "inverters": compounds that cause innate biomolecules to act opposite to their normal function. However, chronic CD treatment in animal models damages auditory cells, which must be addressed before CD can be developed as a systemic drug for atherosclerosis.
BEF12
According to analysis by Dr. James Roberts auditory damage only occurs when CD is administered intrathecally. In the commercially available version "Remchol" is a rectal delivery compound and cannot pass the blood brain barrier.
Learn more: heartfixer.com/Cyclodextrin...
M
Hi Dr.Roberts.
I live in California and wanted to buy Cadavex from the USA web since they have a discount using a discount code, but there is no such web site. I typed Cadavexusa.com, but does not exists. Can you help?
The person Kyle Hodgetts who sells Cavadex and his family have been the subject of many scam investigations on Australian national tv. What they sell is unclear. They answer the phone drunk according to facebook group members of Cyclodextrins, Nattokinase & Cardiovascular disease. You might want to join that facebook.
If you use the Remchol, know that immediate side effects include diarrhea and extreme discomfort, including "blowouts" are the norm, and one person says it happens to 99% of the people. So if doing in the day, you might consider diapers. Longer term, people have gotten Hemorrhoids , cysts, and abscesses the size of marbles.
Remchol, Cavadex cannot be sold in Australia according to an agreement by the accused scam artist Hodgetts and the Australian TGA (equivalent of the US FDA), so he is selling it to Americans on the internet and a non-existent US office that is just a phone number and virtual office.
If you want to experiment with the chemical though, many people are (and not trusting Hodgett since there is no adulteration oversight of Remchol, Cavadex), learn what a proper enema set up is (because the tubes he sells causes physical damage and are not for daily enemas), learn how to administer, and make your own enema. It seems to be what most Americans are doing. If you buy from Cavadex and Remchol, they will not provide you with a COA or third party proof that they are actually using the chemical and that it is made under sanitary conditions. There is a nurse named Billie Starr who has instructions on how to experiment with the chemical yourself. Find it on the facebook group.
What most people seem to be doing instead is using Nattokinase. You might want to read the studies on that. It has reviewed research and seems to remove plaque.
Also, look at that the British health department says about Cavadex in their PAD section. People have been using Cavadex for years now and maybe one person has some improvement in calcium score ( 10% which is experimental noise) that MIGHT be attributed to Remchol, but he was also using Nattokinase too, So who knows? If the stuff worked after one month as claimed, there would be many, many before and after calcium scores showing reduction. There is a lot of anectodal, "Yah, I feel better." Atheromas are not something you feel as they are being formed, so their ability to feel better may or may not have anything to do with atheromas.
Good luck and don't get snookered sending your money to some guy who has many problems. There might be some efficacy, but you are much better off trusting yourself than some guy with serious ethical issues. If you are in the US, many people are selling what they bought since they have decided not to use it and you might get a discount.
Please let us know if you are using the experimental chemical, take baseline vital and calcium scores, and if after a month you have a change. Oh yes, also one guy had kidney damage and learned about it though gfr measurements, so monitor that. Most people are just taking it without really understanding that it is an experiment and they are guinea pigs that need to be monitored often, preferably weekly. But some people are near the end of their rope and are trying anything.
I'm confused...I understand what you're saying about Kyle Hodgetts, but on the other hand Dr. James Roberts (who has no financial interest in the product) is a well-respected cardiologist and he speaks very highly of the product having used it on over 150 patients during the past couple of years so what's the truth here? Is Cavadex a good product or is it a scam?
I do not say it is a scam or a good product. The buyer is to beware and consider the source, the purity, and the history of con-artistry by the seller.
Thanks, I understand your point. I have my first order of it scheduled to arrive in a couple of weeks. The FDA just sent a letter to Cavadex indicating they don't like the way they advertise the product and may block entry of it into the U.S.A.
For the record, I presented info on Cavadex to my doctor a couple of months ago, and as it turns out he has known Dr. Roberts (who is on the videos) for many years and says he's the best cardiologist in the country. Furthermore, he telephoned Dr. Roberts about the product and was told it's a remarkable product that will put some cardiologists out of business. My doctor just started taking it himself and will be recommending some of his patients to also. This is why I am kind of optimistic about trying it, but like you, I am still skeptical and will believe it if it successfully works on my problem (angina).
Hey guys, I have started taking Cavadextrin otherwise known as Remchol today. Have stopped my statins to test its efficacy for 3 months.
Good luck, I hope you get some good results , please let me know how you get on
Hi jezza , hope you are well , are you noticing any positive results from using remchol yet ? Pls keep me posted Thanks
Hi Flagger, I do believe I am seeing some positive results. My BP has come down. I feel better. I was experiencing a bit of impotence as well before starting using it and this has now resolved. On the positive side with stopping statins, my back pain has gone and joint pain I had in my one foot has improved. The real proof in the pudding will be my blood test results in 3 months. Another interesting thing, I normally have a build up of earwax, this has disappeared since I started using Remchol. When I studied this I was surprised to find some studies correlating high earwax with high cholesterol ?? So not sure of the significance of this, but it is an interesting finding. If you are interested I have just set up a group on FB for users and prospective users of Remchol: facebook.com/groups/1538189...
Thanks for that , I have the earwax problem too ! Dry flaky stuff daily, hope you get more positive results, keep me informed pls
I am 75, Vietnam Vet only adding as exposure to Agent Orange can result in ischemic heart problems
Recent CT scan at Mayo Clinic showed severe blockages in lower left heart vein and upper right artery. No angina symptoms. Walk 2 miles almost every day at 3. To 3.5 mph rate.
sstarted cavadex 3 weeks ago noticed BP coming down a bit. ED not cured but have noticed improvement. Had pretty bad edema at ankles when wearing socks. Noticed definite improvement on that.
Hi Jezza_H,
Have you experienced any hearing loss since taking cavadex? Thanks
No, and we have a FB group called Cyclodextrins, Nattokinase & Cardiovascular Disease. No one has reported any impact on hearing.
Hi Jezza, Have you or anyone in the FB group had a new calcium score after using Remchol to compare to your old calcium score so you can definitively state that cholesterol has been removed from your system? Or not?
Also, I looked at Dr. James Robert's website. (He is the doctor on the RemChol website.) He has very desperate patients and used Remchol as part of many possible remedies. He admits any improvement may not be attributable to Remchol. Also, his "data" seems to be through his visual impression of Carotid Intima Media Thickness Test (CIMT) (since he owns that machine and it is readily available to him) and not through a Calcium Score Test which is accurate and read by machines with international standards. In the US, the calcium score, starting at $35, is much cheaper than a CIMT. Aurora Health in Illinois; Edward-Elmhurst in Illinois; Community and Riverview in Indiana; Columbus in Indiana; Indiana University Health; and Hendricks in Indiana, part of the Mayo Clinic group all charge $49 for a calcium score. Luminis Health in the DC area and and Monument in SD charges $75. So, the cost of the before and after tests are much cheaper than the RemChol starter kit of $725.
Also, the price of RemChol seems much too expensive. For example, in the US, Beta cyclodextrin is $17 USD for a kilogram or 1000 grams from an FDA registered facility. Enough for 125 Remchol tubes at 8 grams per tube from an unknown facility. You would then need a rectal liquid /gel (inexpensive and possibly distilled water), and a rectal syringe or injector for $20 maximum in the US. So the cost for 4 months of a do-it-yourself (DIY) equivalent would be about $60 USD maximum versus the approximate price of $878 by RemChol. Plus you wouldn't have all the waste of daily plastic enema bottles.
And again, what is also concerning is that the TGA in Australia (the USA FDA equivalent) has stated that RemChol is not certified to produce the product and that RemChol stated that it will not supply the product after it withdrew all testing of its product for safety and efficacy by the TGA.
Has anyone considered a DIY approach?
Your post has two questions.1) Have you or anyone in the FB group had a new calcium score after using Remchol to compare to your old calcium score so you can definitively state that cholesterol has been removed from your system? Or not? Answer: I have not yet. I have a follow up with my cardiologist later this month. Most people like myself have only been on Remchol for about 3-4 months at the most... I am not rushing back yet to get the CTCA I originally had because I'd like to avoid exposure to radiation. However, I guess I will eventually will do a follow up.
Your second question was: 2) Has anyone considered a DIY approach? Answer: yes, a few have and it is discussed quite a bit in our FB group.
Dear Jezza,
1) Please consider testing with a calcium score if your doctor agrees to swap the invasive, much more expensive, radiation heavier CTCA for a calcium score. It may be good to make sure uncertified RemChol is not harming the body.
2) Would you be so kind as to post where and how to buy the DIY'ers cyclodextrin for rectal delivery? (I am not likely to inject or do intravenously and certainly not intrathecally.)
VSE, I have not gone done the DIY road as of yet, but there are members in our group on FB (Cyclodextrins, Nattokinase & Cardiovascular Disease) that have... you could glean some info from them wrt to DIY. I will explore calcium score option... catching up with a new cardiologist this month... so will be getting more info. Thanks.
I recently visited my doctor and presented the info on Cavadex which he had never heard of.
I told him my dilemma- On the one hand the owner of the company has a "shady past", but a doctor named James Roberts is claiming a lot of positive results and that I felt Dr. Roberts was legitimate...My doctor responded that he knows Dr. Roberts very well for many years + that Dr. Roberts is "the best Cardiologist" in the country. My doctor will be calling Dr. Roberts to discuss this product and he may be able to offer it to his patients soon if it is as good as Dr. Roberts says it is.
Hi Jezza_H
I wanted to share with the group and you information that was taken down from your facebook group for a business address that had already been in two separate postings for months in your facebook group. I understand that many people were greatly benefitting from from it and you deleted the posting and account. It also appears that others who have been critical of RemChol are no longer posting information.
The post you deleted is reprinted below in part from what I saved because it had invaluable information.
Self experimenters are using Austrlian Remchol. RemChol has not provided third-party proof of formula, purity or sanitation in the manufacturing or repackaging of their chemical. Mike R. has his Remchol package delivered from an illegal company not registered in Australia with a “business address” of a house with a very big garage which gives a clue that the chemical is not high quality ACS, USP, NF, or Food grade. High quality chemical grades have specific storage and distribution requirements and would not come out of a house. So RemChol, absent a COA, might be industrial or a laboratory grade and repackaged in an unknown facility or house. One googled explanation is at laballey.com/pages/chemical...
Both Darren G. via intravenous, and nurse Billie S. via water enema, trust and use the following 2-Hydroxypropyl-Beta-Cyclodextrin made by RND Centre Inc and distributed in 100 gram powder bottles by Amazon amazon.com/gp/product/B00HR...
Larger quantities can be purchased at rndcenterinc.com/search?q=c...
Billie uses the following enema syringe: amazon.com/gp/product/B0C27...
Nurse Billie S. Formula III is summarized as follows: First two weeks, only use a half- dose or 4 grams. Regular dose is 8 grams. 16 grams (sold by RemChol) is excessive and wasted since the average person can only hold 10 ml water in an enema. Two (2) hours before, discontinue eating completely, consider eating less fiber and fats beforehand. (1) hour before, use a saline enema. Then defecate and the cyclodextrin is easier to hold up to six hours with “no blow out.”
Mix 3 teaspoons or mix 10 grams generic 2-hydroxypropyl-beta-cyclodextrine with 10ml slightly warm sterile water in a snack baggie and squish it around until melted, let it sit, it will melt slowly though it may not seem like it. Put it in enema bulb, syringe or bottle and apply. Disinfect the bulb, syringe, or bulb after use. This is the exact same formulation as RemChol in a small plastic tube that many have discontinued to use because they cannot self administer. The sticky chemical can also adhere to the inside the tube and be wasted. The hose and syringe does not have these problems.
Cost discussion: Many people cannot afford the experimental chemical at the price that RemChol charges. Remchol charges $625 USD for 768 grams in 96 tubes with 8 grams each. The same amount from RND Center Inc. would cost $230.32, for a savings of around $395. RemChol charges $225 USD for 240 grams in 32 Tubes for 1 month supply. The same amount would be $71.98 from RND Center Inc. for a savings of around $153.
Question for RemChol experimenters: Why not buy in bulk directly from a reputable company for an even lower price than doing it yourself?
Question for RemChol experimenters: Why not hire a compounder or pharmacy to make the enema or IV in FDA-certified facilities and ship directly to experimenters? Compounders and pharmacies will likely get an even deeper discount.
Hi VSE, even though a physical address may have been shared in two previous FB posts, once becoming aware that personal information is being posted on a FB group there is an obligation to remove it. Had the personal information been observed within the first two posts, they would also have been removed as well.
There is no issue with people sharing their opinions, but there are protocols that need to be adhered to. If someone shares a physical addresses/mobile numbers/etc without another person's consent in a public forum and there is a complaint (which there was), then there is an obligation to act.
That address was a residential address in Queensland (even though it might have been cited as a business address). For those reasons it was taken down.
The user that posted it was suspended for two weeks to emphasize that it is important to not share personal information online... which is also listed in the rules for the FB group. People are encouraged to share openly. Individuals should be allowed to make up their own minds with all the information at their disposal.
You blocked a publicly known BUSINESS address that sells the latest cure for heart disease. You sua sponte, without legal advice, and under pressure of cholrem / cavadex advocates, took retaliatory and harmful action to protect Cholrem's business address. This was NOT PERSONAL information, but a business address that publicizes the location.
What you did was wrong and legally improper under US law, where FB is hosted and whose laws apply. I suggest you hire a US attorney to discuss what you did, retract your decision, reprint the posting, and add an apology for attacking the integrity of the poster.
And you should also be forthright that on FB, you along with others who have claimed improvements with Cavadex are also starting many other drugs and self-help remedies or cocktails and CANNOT be attributed to Cavadex. Moreover, you removed the name cavadex / cholrem from the FB name because many are using other self-help possible remedies and medications and not cavadex / cholrem.
What a bizarre response, strange assumptions and projection - further affirming that the action taken to remove the FB post was the correct one.
Stopping your Ned's was not recommended...that's dangerous. Your improvements will show with or without stating. Statins from my understanding thins the blood DOES NOTHING TO CLEAR ARTIERIES
I think you meant stopping my "meds" was not recommended. Sure, but I can make my own decisions and I did them in consultation with my GP. My body, my life. However, I find your response contradictory... so on one hand you're saying I should not stop taking my meds... which happened to be statins... then on the other hand you're saying taking statins will not help to clear my arteries (which I never said they did), and then you say that I will see improvements with or without statins... so a bit contradictory?! So if, like you say, I will see improvements without statins, then why say I should not have stopped taking statins ?
Stating from what I'm told thins the blood. It's not going to clean up plaque or remove plaque. But it is less likely that a clott can form. We take them to stay alive. We search for answers because our doctors only course of action is to open us up and change things around. They have nothing, to offer. Nor do they care to as the pay days are great for them. Will this product work, we can only hope that to some degree it does something.
Good morning Jezza. Thank you for the info. I have also just ordered 4 months of Remchol. I plan on staying on statins but hope this chelation enama helps melt away some plaque. How are u feeling? Any negative side effects? A big thank you for any additional information you can provide.
Hi Tim, I am feeling fine. I have just finished my second box of Remchol. I am planning to see my GP this month and get another round of blood tests done. No negative side effects thus far that I've noticed. I have started FB group called Cyclodextrins, Nattokinase & Cardiovascular Disease to try to get more insights from other people like me that have started the product.
Hey Jeeza, hope all is well. I think we are both 3 months into Remchol. I am feeling awesome, just not sure if plaque has been reduced. I have noticed other positives. So hopeful. How about you? Blessings
How did it go? It's at the 3 month point.
Hi all, I have finished three boxes of Remchol now, and started my fourth. This is the last of the batch because I bought four up front.
It is hard to say if it is reversing my atherosclerosis.
I feel very similar. Just after taking it, my ED resolved, but someone else mentioned that ED can be caused by one's mental state of mind, and I didn't have ED for long before starting Remchol... so it going away might not be directly related to Remchol use. My earwax also dissappeared, and there are some links I have shared previously showing correlation between earwax and atherosclerosis.
The biggest concern for me still with Remchol is the lack of human studies.
What I can say conclusively is that Remchol does not reduce serum cholestrol (the cholestrol in your blood). This I confirmed by stopping my statins (**yes, after discussing with my GP **) when I started Remchol and I continued this from 13th September 2023 to 8th December 2023. NOTE: it is not recommended to change any of your existing dosages and removing existing medication without first consulting with your GP or cardiologist.
During this time with Remchol only (and no statins), my cholestrol jumped up significantly... from: 5.6mmol/L total in September to 7.5mmol/L total in December, and LDL from 3.5mmol/L to 5.5mmol/L.
So Remchol did nothing to help my serum cholestrol. All the feedback on the website, however, was that Remchol removes crytstalline cholestrol and not serum cholestrol... so many were not surprised by this result, but in case you were wondering... no need to test this out... I already did this. Needless to say I started taking my statins again.
So the only way to know for sure, is for me to go back for a CTCA at the moment to see if there has been an improvement in my calcium score. Right now I am choosing not to do this because I don't want another big hit of radiation right now that I don't think I need yet.
However, through all of this I did come across the NIH research ncbi.nlm.nih.gov/pmc/articl... done with Nattokinase on humans that absolutely does show a significant reduction in atherosclerosis.
Because of this I have also started taking Nattokinase (12000FU/daily) which I started whilst working through my third box of Remchol. I would rather include a product that I know absolutely does have confirmed results, and I am going to finish my fourth box of Remchol which I have bought anyway, and just started.
I am also going to see a new cardiologist in March 2024 to discuss others ways I can look at testing plaque reduction other than having to go for a CTCA every year.
To be honest right now I have more faith in Nattokinase than Remchol based on the 10,800 FU day study I shared above, simply because it has confirmed AND published results which is Remchol's biggest issue it has right now, ie: no published human studies.
Cavadex the company that produces Remchol seems content to rely on anecdotal evidence from their users, this may become their achilles heel, even if the product does work.
So imagine this: you have Nattokinase which has confirmed and published human case studies showing significant atherosclerosis reduction within 12 months. Nattokinase is cheap and easy to take (you just pop a tablet orally).
You have Remchol which has no published human case studies, but does have some positive anecdotal feedback. Remchol is very expensive and not pleasant to administer (as it is an enema treatment).
What would you do ?
I am currently taking both Remchol and now started Nattokinase.
Remchol may work, but my faith right now is more in Nattokinase as something that I would use long-term based on the cost, ease-of-use and published studies.
Hi, I've also looked into nattokinase and the results look promising, could I ask where you purchase it from and do you get the 6000fu tablet and have dose of 2 per day ? Or is there a 12000fu tablet ?Thanks in advance and good luck
, pls post results
I bought Mecisco Nattokinase off Amazon Australia. It contains 60 tablets each with 4000FU. I haven't seen a tablet greater than 4000FU. Most appear to be 2000FU tablets.
I am doing the exact same thing...Remchol and Nattokinase. I also have reservations about Remchol with no rock solid studies...but I figured it can't hurt...only help. My only concern is, after a year...if there is improvement...we won't know which protocol was responsible.
I'm planning on taking Remchol for 4 months then continuing with Nattokinase, and am planning maybe to test with another CTCA in a year. Will also be asking my cardiologist what other tests we can run without getting radiation exposure. I guess if there is atherosclerosis regression at that point in time, I may just continue with Nattokinase for another year.
By then, hopefully, there will be more feedback and results from others on just a nattokinase protocol, or just a Remchol protocol to assess further. Maybe one needs Remchol with Nattokinase as well ?
We are the guinea pigs, unfortunately, or fortunately, depending on how you view it.
A big thank you for your update. I am also on Natto and Remchol( also statins and Rapatha). Feel good but won't know about plaque reduction until new calcium score test. Have u noticed tooth enamel deterioration? Ugh. I really believe it's from heavy statins. Thx
Thank you Jezza for confirming that Cyclodextrine, and specifically RemChol does not change serum cholsterol. Thank you for going off meds (with your doctor's oversight) specifically to test for this.
Several reviewed medical journal articles have stated that cyclodextrine will not affect serum cholesterol. Yet RemChol owner Hodgetts claims that his serum cholesterol became "normal" after taking his product.
As to "Remchol is very expensive," you are correct. I estimate that you can duplicate the product with product from an FDA approved facility for about $60 versus the $878 RemChol would charge you. He's out to make money from desperate people and it appears he has a history of schemes that has landed his family in trouble in Australia.
Also, I strongly recommend you get a calcium score as a baseline before trying methods to reduce arterial plaque. A Calcium score has much less radiation than a CTCA and is non-invasive because there is no dye injected into you. Also, the calcium score ($35-100) is so much cheaper than a CTCA that costs on average $350 to $750 in the USA.
Like you, I am willing to be a guinea pig too. I am on no medications by choice, I became vegan after reviewing Dr. Esselstyn from the Cleveland clinic food quidelines. This was tough because I grew up eating steak for breakfast, steak for lunch, steak for after-school snack, and steak for dinner. After turning vegan, my serum cholesterol decreased by 51 points from 2/14/2018 to 4/11/2018, specifically from 228 to 177 mg/dL. My calcium score decreased by 13%. Unheard of said my doctor. However, fast forward to 2024 and my cholesterol SHOULD BE 140 mg/dL which is the average VEGAN serum cholesterol, but mine is still around 177. That is a danger zone for a heart attack. 150 is generally recognized to be heart attack free range and below 70 mg/dL (1.8 mmol/L), you stop adding to plaque. I am not there.
Note, as a vegan I overdid it on "whole wheat" pastas, sourdough bread, faux meats thus driving my triglycerides into overdrive. I followed Dr. William Davis reluctantly and cut out all wheat (yet kept my daily morning oatmeal). TG's plummeted.
Clearly, I am not the average vegan. Today I am taking the Boston Heart test through Empower DX to see if I am a cholesterol overproducer via the liver or an overabsorber via the intestine as is advocated by Thomas Dayspring, a respected lipidologist.
I gave information to my doctor about RemChol. He said it was interesting, and he is also a doctor who recommended I go vegan. (Four cardiologists have shared socially that they have never done open-heart surgery on a vegan.) He had me do another calcium score to get a new baseline if I am going to experiment on myself (with his oversight).
So Jazza, please keep us posted. I will do the same. PS, I am a trained chemical engineer from an internationally respected college, so I am just as qualified as the RemChol computer game coder Hodgetts to experiment on reducing cholesterol.
Began Remchol one week ago. I am doing the "aggressive" treatment which is twice per day for 4 weeks....then twice per week over the next year. I plan on having blood work done in one month to check cholesterol levels. I plan to have a Calcium Scan done in one year to see if there has been any reduction.
have you thought about the vitamin k2 , it blocks calcium from entering artery walls when attached to cholesterol. The k2 keeps calcium in the bone where it belongs, therefore preventing any additional buildup. It will not clean out what’s already there. Garlic extract and bergamot will help clean somewhat.
Remchol doesn't reduce serum cholesterol and this I can personally confirm. It apparently only reduces crystallised cholesterol which I haven't been able to confirm personally yet.
Hi TangoFoxtrot, Can you possibly get a Calcium Scan soon so we know if it actually works? One year later might not actually detect Remchol plaque removal. And if it doesn't work for you, you might consider stopping it until you know what it is, purity, and if is comes from a sanitary, certified facility.
Also, medical literature agrees with Jazza that Remchol as cyclodextrin does not affect serum / blood cholesterol.
pity NK can’t be taken with anti coagulants
also if NK does what the Chinese retrospective study suggests i. E dissolve plaque which our NHS and BHF say is impossible - where does that leave us?
Try and see ?
I can’t as not recommended with anti coagulants?
Hi Flagger,
I may embark on the Beta-Hydroxypropyl Cyclodextrin (CD) rectal treatment with the chemical known as Remchol, Cholrem, and Cavadex and provided by Australian Kyle Hodgetts who wrote up his own treatment as "research." In his video, this electronics engineer claims he had 5 blocked stents, including stents within a stent, and was told he had less than 6 months to live. In videos, this 58-59 year-old man appears to be (morbidly) obese lifestyle with "22 standard drinks per day and 20 cigarettes per day," and was on "antihypertensives, anti-cholesterol, and antiplatelets."
He claimed his blood triglycerides, cholesterol and LDL became normal. This is of note since published research has indicated CD will not change blood serum lipids, only cholesterol found in plaque. (However, it is possible that Hodgett's body was so severely damaged that some removal of plaque "restarted" some of the body's natural mechanisms to remove cholesterol.)
Of note is that Hodgett claims "reduction in plaque size in the arteries, from 6.7x5.0x2.0mm to 6.1x4.7x1.7mm." This is where a lipidoloist would need to tell us if this is a reduction that makes a difference. See Hodgetts author of "Cyclodextrins show promising results in cardiovascular disease through improvement of the lipid profile and regression of atherosclerosis" found in his product website under research.
What is curious is that Hodgetts self-experimented in about 2019. He has had 4 years since then to update with more evidence from self-experiment, but he has not.
As to Hodgett, several people have claimed he is a con artist who, along with wife Rachel, defrauded them in various schemes, some of which were reported in 2014 by "A Current Affairs" investigative reporters. Hodgett waited till 2017 to sue for $2.5 Billion Australian dollars, claiming he was ruined by the report. He lost in 2020 to participating litigants in Hodgetts versus Nine Networks Australia. He represented himself. During this litgation, Hodgetts discovered and administered CD on himself and reversed plaque.
Prior to this case, a "second generation con-man, Adam Hodgetts, was sent to 4 years in jail for internet fraud. His defense was that, "the young man had initially been lured into a life of fraud by his father, with the pair both suffering alcohol and gambling addictions. But this did not excuse his behaviour, Judge McIntyre said," according to news. com. au
But even if there were some cholesterol removal with CD, there is the matter of what is put into the rectal tubes, and how pure and sanitary are the products. In Austalia, neither Cavadex nor RemChol "may be supplied" by Hodgetts' company Cholrem by the Therapeutic Goods Administration TGA. An application was reviewed, a decision was to come out on July 10, 2020 and be published September 2020. Hodgetts cancelled the review on June 24, 2020. Thus, the products are "no longer permitted to be supplied," the "safety" and "efficacy" of the product "was not assessed as part of the review," and the Hodgetts "sponsor cancelled the medicine and withdrew it from further supply." So it appears it may be illegal for Hodgetts to supply CD in Australia.
So there is no 3rd party oversight or govenment approval of products by a man who admits he knows nothing about medicine but he can cure the number one cause of death in the world and might not be coherent with 22 drinks and 20 cigarettes per day.
I think I just talked myself out of sending good money to Australia. Too bad because I had taken a calcium score and run blood panels as a baseline prior to its use. If a reliable CD equivalent is available, please advise.
Hi VSE, there appears to be a new company exploring their cyclodextrin called: UDP-003 for atherosclerosis regression: cyclaritytx.com/our-science/
Please consider reading the 2022 open source and free reviewed research "2-Hydroxypropyl-beta-cyclodextrin Treatment Does Not Induce Atherosclerotic Lesion Regression in Western-Type Diet-Fed Apolipoprotein E Knockout Mice" The researchers do not find CD to reduce plaque and attempt to replicate 2016 Zimmer experiments, but find it does not reduce plaque in living mammals, though it did seem to work in vitro test tubes. The Kim article referred to discussed the very short half-life of CD and the need to have high doses that appear to cause ototoxicity (deafness) even when administered by injection and not intrathecally (into the spine as in Niemann Picks children).
If someone does review, can you please let me know what your thoughts are?
There is discussion that perhaps a polymer of CD might be explored for possible plaque reduction.
Thanks
Poconoboy You may find this conversation of interest
Please look under "PAD / CAD treatment" to see BHF updated position on cyclodextrin.
BHFnurse_JulieBHF Nurse
7 years ago
Hello,
We read your post with interest here at BHF and discussed it amongst our medical team.
Clinical trials are needed to understand whether cyclodextrin treatment would be safe at the doses needed and any more effective than statin treatment. Patients with the rare and fatal Niemann-Pick disease are in desperate need of a treatment, and so there are beginning to be proper trials in these patients of safety and efficacy for cyclodextrin – which has to be infused intravenously or, in the case of the mouse experiments referred to, injected subcutaneously (under the skin) twice a week.
We will wait to hear the progress of these trials and comment further as/if/when evidence of effectiveness is proven in humans.
In the meantime we would stress that everyone take their usual medications for PAD/atherosclerosis as prescribed by their doctor.
Best wishes,
Julie
******************************
4 days ago
Hello again - I do hope this post finds you well.
I forwarded your query as above to our Research department and here is their response:
We haven’t found any BHF-funded research looking specifically at that compound, but have found a few animal atherosclerosis studies using Cyclodextrin generally:
europepmc.org/article/MED/3...
They are using cholesterol-methyl-b-cyclodextrin to deplete cholesterol as a model of reduced atherosclerosis in mice.
Cyclodextrin as an atheroprotective is in animals only at this stage, and we have also found a few studies suggesting harmful effects:
pubmed.ncbi.nlm.nih.gov/344...
pubmed.ncbi.nlm.nih.gov/291...
There is some pre-clinical/ex-vivo human evidence that Cyclodextrin might help with atherosclerosis progression, but not much conclusive evidence from clinical trials. This small trial shows a slight reduction in small LDL from 12-14 weeks of Cyclodextrin :
clinicaltrials.gov/study/NC...
So, in conclusion, there still is an evidence gap in terms of human data supporting any beneficial effect for atherosclerosis, and a need for randomised controlled trials before anyone should be advised to take it as a supplement.
All the evidence the below company give in support of their product is also in mice and there is even one study where they just placed the compound onto a person’s plaque biopsy, so definitely far off the type of evidence we’d use to advise actual people.
Home (remchol.com)
I do hope this information is useful and very best wishes to all.
Julie
Looks like a large scale and longevity study is missing. Otherwise, hard to proof placebo from causal effect. Despite their reputation, statins are poven and have been studied for a very long time. I get that it is not suitable for everybody, but doubt there is a magic bullet hiding somewhere.
Cavadex is not approved by either the US FDA or Australian TGA. Beware
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