When you are diagnosed with AFib, then it is absolutely necessary to take blood thinners for as long as you have the problem, as blood can pool in the heart chambers and produce a clot. I take Elequis and was also formerly on Pradaxa (dabigatran). Both are excellent drugs with no side effects and little monitoring. I will be taking this twice daily for lifetime now, as my AFib is permanent.
Bisoprolol is a commonly used drug for reducing blood pressure which will help the heart, but there those of us who just cannot tolerate the side effects from this. Many others have no ill effects at all. For myself, I felt dreadful, like I had lead weights attached to my legs, tired, aches and pains, very lethargic and rather depressed. There are alternatives to this drug, although in my own case, I now take normal blood pressure medication (there is now a brilliant new one called Lercanidipine) and not Bisoprolol, which I would not agree to take again. Consult your doctor and ask to find an alternative for you if you feel you cannot tolerate Bisoprolol.