Ethnicity and Behcet's

ncbi.nlm.nih.gov/pubmed/119...

Hi Rooki, the link above will help you further to understand this disease, true, that my Son has it, Neuro Behcets, the most serious dangerous kind as mentioned in this article, he has brainstem/pons with pontine encephlitis, my unlucky son had childhood kawasaki disease (of asian children predominat) and now he has B.D. of Asian predominat...but the population pattern mentioned in this artilce is also interesting, I have written to this doctor, but have not had any response...I think if you wish you should write to her, she would be helpful....thank you for your post, and wish you well, and please be safe, from what I understand in this article, I think it is imperative that you get Neurology/MRI check up...it was too later for my son....best for you, Ashveer and his loving mother here...genetically, we are from North India, so no surprise here, I guess it depends how the population spread from silk road route to outskirts - we sent our son's blood work to National Institute of Health, as they found his vasculitis to be unique - I wrote to them online after reading many articles like you online, and to my surprise, they wanted to see my son's blood work, and I think you could try NIH.Com, or do a expensive Whole Exon Sequencing WES Genetic Test (must through your doctor), that will tell you about your genetics and disease activity, as for my son, they are still studying his disease, and I don't know what they will tell me as it is for research, hopefully they will tell me something in the next few months...

Not African-American but ancestors are mainly Norwegian. I did my ancestry DNA and found that my Viking relatives had a hay day down in the Mediterranean area. We are so intertwined in the world today that I think anyone can get anything. Not sure where you live but here in the U.S. the hardest part of this disease besides being diagnosed is finding a doctor who knows how to treat it. It took me 16 years to be diagnosed and it was by my lung specialist. As far as I know there is only three doctors that deal with this disease.

Hi rooki,

I am African American but my mother is Syrian which is Mediterranean. So I do not know if that plays a big part in why I have the disease. No one else on either side of my family has it. But also a lot of my mothers family is still in Syria so an extended family member that I’ve never met could possibly have it. You could have some middle eastern ancestry from long ago but if not anyone from any race can still be affected

Hi all. I am Mexican and have Neuro BD. I only know my about my blood line from my family. We come from the Mayan tribe. My great grandparents are still with us. They are my main sourse of information. My son is 15, Mexican & Salvadoran and has BD. I am about to start a chemo treatment and my son is beginning acupuncture treatments for Juvinal RA, mainly in his shoulders and hands. We are located in Northern California and there aren't any doctors who are familiar with this disease. I finally found a rheumatologist in Napa CA who is treating me. This is a rough disease and wish all of you well.

Thanks for your response and I pray that you go into remission.

Rooki

I am a african american female with no close lineage to the commonly affected races. I also have neuro-behcets.

Thanks it has been a rough road but im not giving up. 😊 hoping for remission for you as well.

SavageV, do you have the most serious kind, Paranchymal N.B. My son has dysartheria now, and right arm shaking as lesions are in the brainstem/pons, but there is the venous type that is good recovery prognosis, it is my son's that is mengineoencaphilits type that has poor prognosis....Neuro is very much sub dividied...hope you are well

How many of you have been tested for the HLA B51 gene antigen? What we all have to remember, is going back even 10 generations will not tell us where our gene base all came from We are all a mixed bag and most of actually started out in only one of 3 places. So the odds are higher than we understand. The HLA B51 predisposes to Behcet's, I believe the worst type is indicated is this gene is found. People without the disease carry it too and may never get the disease. People without the gene also get Behcet's. There is another gene, I understand, but I am less aware of the link, HLA 20. A friend on here has more understanding of the latest thinking on immune disease linked to that gene I suspect. It all fairly new.

Above all, where we live means nothing, we are all a mix of everything

Hi I’m not African American but I am a black woman with behcets I live in England. My parents are from St Lucia and Jamaica x but going back in our family we are a definitely a mixed bag so 🤷🏽‍♀️

Hi,

I am African American. I have a lot of autoimmune cracks in my family including lupus, fibromyalgia so there are underlying issues in my genetic set up. But I also had a huge load of strep at one point in a response to a bad reaction to antibiotics which is also a known trigger. There are infectious pathways to this crazy disease on top of genetics.

Hi,

I'm African-American with some Native American ancestry and I have BD. I do however have several family members with other autoimmune diseases.

I am Dominican. Both parents but born in New York, New York.