Ladies and Gentelman, I am sorry that this study has not been published on every ataxia, huntington, parkinson, etc forum, but this morning I found what I consider the Holy Grail of trehalose studies. This was a double blind human clinical trial of oral ingestion of trehalose. The study proved trehalose ingested orally improved blood flow in elderly patients. This means, ladies and gentlemen, that eating trehalose gets some of the molecule into the blood. I realize this does not go so far as prove that the trehalose molecule can then continue on to the brain, but it is a HUGE step forward and should give every neurologist who is treating ataxia patients a giant moment of reflection.
Oral trehalose supplementation improves resistance artery
endothelial function in healthy middle‐aged and older adults
For those who don't want to read the details I will say this: in the study patients ate 100g daily and there were two reported problems 1) intestinal upset and 2) some patients gained weight. Otherwise 100g daily of trehalose was tolerated and efficacious.