Have just been changed back onto flixotide from symbicort. Its a large dose 1000mcg twice daily via an accuhaler, i've been onit before and it caused no problems. This time I have a swollen (just because its sore), cracked tongue with red bits on it. I have tried nystatin, difflam, bonjella and corsodil without affect. Its so sore now I can't eat (not that will do me harm) or drink much. Has anyone had a similar problem. I have had to stop taking it its so painful.