I have just changed my seretide 125 to a seretide 250 accuhaler. I have been troubled by sores in the corner of my mouth which just don't seem to heal. They are red, sometimes split and sometimes get crusty. After much searching on the web I came across a site which said they were caused by steroid inhalers. Always used a spacer with the 125 but can't use one with the accuhaler. Has anyone else had this problem. Look forward to hearing from you.