Omoprazole : Hi I think there will be... - Lung Conditions C...

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Alice70 profile image
42 Replies

Hi I think there will be many on our site that takes omoprazole ,because I am taking 30mg prednisalone, and they upset my stomache so much ,I am taking two omoprazole a day morning and night to knock back the acid ,I find omoprazole dampens down the acid ,but gives me massive stomache bloating which to me is as bad as having the acid as the bloading is making me feel more breathless ,anyone else find this with omoprazole

42 Replies
Bevvy profile image

Haven’t had issues such as yours. Suggest you speak to your gp (maybe after discussing with your pharmacist) about the problem. There are other medications that work in a similar way, that might not give you the side effects you are experiencing.

Alice70 profile image
Alice70 in reply to Bevvy

Yes I'm not going to omoprazole agian always have trouble with them

Maggie_Mae profile image

I’ve personally been ok

Maybe worth taking a wee note of which foods & drinks you are currently taking and keeping an eye if they possibly effecting?

Possibly also maybe other medications that cause constipation, leading to bloating

Obviously if your still concerned speak to your GP or practice nurse to rule out if anything else going on ( hint think on your foods & drinks as probably first Q asked & you can rule out right away! 🌹

djbctla profile image
djbctla in reply to Maggie_Mae

hi Maggie_Mae

Make sure you take omoprazole 30 Minutes before food, I leave my 2 beside the bed with a glass of water. Bernardine

Maggie_Mae profile image
Maggie_Mae in reply to djbctla

Thankyou … 🌹. I work in healthcare in community , but I’ll be truthful with you im on that much just now ( due to recent hospital A&E visit ) my heads spinning lol

I actually sorted out wee bag today of medications as I didn’t know if I was coming or going 😂😂

Alice70 profile image
Alice70 in reply to Maggie_Mae

Not constipated think it's omoprazole and me not suited

Maggie_Mae profile image
Maggie_Mae in reply to Alice70

worth talking to Your GP team then 🌹

Maricopa profile image

How long are you taking 30 mg prednisone for?

Alice70 profile image
Alice70 in reply to Maricopa

6 days can't take anymore because of reation I get from them

Maricopa profile image
Maricopa in reply to Alice70

I thought wow, long term use of that high a dose. Yikes! I’m on 5mg and azithromycin 3x a week. The prednisone has definitely done damage to me. But I’m stuck between a rock and a hard place.

Patk1 profile image

I'm on omeprazole + hav b for yrs with no maybe yr inflammation thats causing symptoms? I have ibs and buy buscopan which relived cramps and bloating

Alice70 profile image
Alice70 in reply to Patk1

Just taken a buscopan

Patk1 profile image
Patk1 in reply to Alice70

Hope it helps you.ive tried merbevarine but I find buscopan better x

Injecter1 profile image

perhaps ask to try an alternative…. Lansoprazole works well.

Morrison10 profile image
Morrison10 in reply to Injecter1

Yes I had problem with Omoprazol, so now have Lansprozole

bluepuddy profile image

Hello Alice,

Had problems with omoprazole, so have put them on my allergy list.

Alice70 profile image
Alice70 in reply to bluepuddy

Good idea

bluepuddy profile image
bluepuddy in reply to Alice70


pegbl profile image

have you tried asking your go for gastro resistant prednisolone, they really help me a lot no longer need omeprazole. Xxx

Alice70 profile image
Alice70 in reply to pegbl

Nurse suggested them ,but gp said not as affected

pegbl profile image
pegbl in reply to Alice70

They are, but more expensive I think he’s just saving money. 🙈

ladyn profile image

hi Alice. When I have to take steroids, I take Nexium. It’s one a day. I buy the capsules and they are expensive. But they really do help.

These ones
slram profile image
slram in reply to ladyn

There is a class action suit here in the US against Nexium, proven to cause stomach cancer and kidney failure. Try to go "natural".

ladyn profile image
ladyn in reply to slram

Has anyone here in the UK heard about this?

slram profile image
slram in reply to slram

Try; but you being in the UK, it may or may not come up.

Alice70 profile image
Alice70 in reply to ladyn

Thank you ladyn

Tykelady profile image

Is the prednisolone a permanent dose or just the rescue pack flare up dose?

Alice70 profile image
Alice70 in reply to Tykelady

Rescue pk gp gave me extra ecause chest isn't clear

Izb1 profile image

That seems like an awful lot of Omerprazole, what is the mg of your tablet. I only take one 20mg per day. Think you should speak with your doctor x

Alice70 profile image
Alice70 in reply to Izb1

I usually take one 20mg rhree to four times a week ,when on prednisalone my stomache gets recked ,even though I increased omoprazole still getting upset stomach

Izb1 profile image
Izb1 in reply to Alice70

You say in your post you are taking 2 morning and night, does that mean you are taking 4 tablets a day ?? You should only be taking one per day. Not sure if you are mistaken on dose as you now say 3/4 times per week ?? Think you should speak with your doctor x

honeysuckle78 profile image

hi re omoprazole .. it’s a big no from my stomach I’ve got my ibs under control thanks to many things I’ve altered in diet especially being lactose free and rarely wheat .

But that drug ripped my insides out and I was in agony. though my dr insisted it wasn’t the cause ..bloating and terrible pain .

I know a few people on it who suffer worsening gut problems whilst on that medication, but they assume it’s another cause.. because their g.p. Says it’s to stop gut problems .

I can’t tolerate lots of medication so introduce new things quite scientifically.

I take bio kult for my gut it’s a lifesaver.

Charlie_G profile image
Charlie_G in reply to honeysuckle78

The really stupid thing there is that bloating and GI discomfort are considered common side effects of omeprazole. In medical terms, common side effects are those that effect at least 1 in 10 people that are taking a drug, so have to happen a lot to make the list. Your GP could have found that information in about 30 seconds using the BNF, but when you consider the mechanism is to prevent acid production, and therefore interfere with digestive processes, it’s not a leap to realise that it could well have unwanted gastro effects for some people.

Alice70 profile image
Alice70 in reply to honeysuckle78

Same hear I haven't got the best stomache for tablets

Charlie_G profile image

With the caveat that I’m not medically qualified. As with Izb1 ’s reply, what dosage of omeprazole is that a day, and if it’s more than usual, have you run it past your doctor first? There are a couple of specific conditions where really large doses are used, but generally speaking, the absolutely maximum dose for most ‘normal’ gastro conditions is 40mg, either as one dose or split morning and night. But it is only on a medic’s advice under the correct circumstances, so if you’re taking more than 20mg a day total, I’d encourage you to speak to a doctor. Aside from obvious side effects, which can include bloating and gastrointestinal discomfort, it’s also always worth keeping in mind that PPIs like omeprazole are not without issues: they are known to cause vitamin deficiencies, be a factor in osteoporosis, and can also mask symptoms of cancer. Without a PPI, I have reflux so severe I routinely have acid coming out of my nose, but using them at higher doses and/or long term is not something to be done without consideration and medical guidance.

Izb1 profile image
Izb1 in reply to Charlie_G

I tried to come off this when I had my gall bladder removed but the pain was so bad in between my shoulder blades and chest it really feels like a heart attack and lasts quite a long time, this has happended a few times when stopping taking it, but would really like to stop. I tried slippery elm but it didnt seem strong enough to stop this pain x

Carsok profile image

Not sure how long you're on prednisone for but I was on 30 mg for over a year (Giant Cell Arteritis) and it messed everything up in my body from my stomach which started to look like I was pregnant, gave me the moon face, the hump on my back and it affected just about everything in my body. About 6 months ago they started me on it again and after about a month I had to stop it because it affected me mentally besides the rage from prednisone. Not sure why you're taking it but I am now on methotrexate and I give myself a shot once a week for my joints and the difference is amazing. I find now in medicine you have to be your own advocate and if something is not working for you go speak with your doctor and maybe they can find something else. Hope things get better for you.

Izb1 profile image
Izb1 in reply to Carsok

Do you remember 2greys, he came of this and went onto splippery elm but had to adjust the timing, I cant remember everything he said about it but i have considered trying this out myself. I am also on methotrexate . What is the shot you give yourself once per week ? Is this a vitamin x

Carsok profile image
Carsok in reply to Izb1

Methotrexate. It's prescription. I take .6 ml once a week. I couldn't take the pills as they upset my stomach way too much so it's easier with injection once a week. It's used for RA and psoriatic arthritis, which I have. Helps the joints quite a bit. I also get shots in my lower back every 8 to 12 months.

Izb1 profile image
Izb1 in reply to Carsok

Ahh makes sense, I take the tablets, which dont seem to help alot but the shot I have when things get out of hand are marvellous and seem to settle the ra for months, I think they are steroids x

Fircone profile image

Hi Alice, I used to take omeprazole for acid reflux but I was sure it was making me far more breathless and bloated. I weaned myself off them over a period of months and my breathing was so much better.

teenieleek profile image

Yes, it gives me wind. Much prefer gaviscon.

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