A McMaster University-led study has teased out the reason for blood clots caused by COVID-19, a serious potential complication of the virus.
Blood from critically ill COVID-19 patients contains antibodies that can contribute to clotting, says Ishac Nazy, associate professor of medicine and director of the McMaster Platelet Immunology Laboratory. These antibodies form immune complexes that activate platelets, the cells that lead to blood clotformation. Some blood-thinner medications can block these immune complexes and potentially reduce clots.
“By discovering the mechanism, we can inform doctors on the use of blood-thinners, known as anticoagulants, that can stop the clotting in COVID-19 patients,” said Nazy, whose findings have been published in the Journal of Thrombosis and Haemostasis.
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Journal of Thrombosis and Haemostasis. Study Paper: