Immunological memory after SARS-CoV-2 infection recovery. *The welcome news we have been waiting for*

[2greys]

Until now, it was unclear whether a survived SARS-CoV-2 infection or COVID-19 leads to a persistent immunological memory and thus can protect against a new infection. Several studies had shown that SARS-CoV-2 specific antibodies are only detectable for a few months in many people who have survived COVID-19 and may therefore only provide temporary protection against re-infection. A research team at the Medical Center—University of Freiburg led by Dr. Maike Hofmann, Dr. Christoph Neumann-Haefelin and Prof. Dr. Robert Thimme has now been able to show: after recovery from SARS-CoV-2 infection, immune cells are formed which remain in the body and could mediate a rapid immune response in case of re-infection. The Freiburg study was published in the online edition of the renowned scientific journal Nature Medicine on November 12, 2020.

"These so-called memory T-cells after SARS-CoV-2 infection look similar to those after a real flu. We are therefore confident that the majority of people who have survived SARS-CoV-2 infection have some protection against re-infection with SARS-CoV-2," explains Dr. Hofmann, a scientist at the Department of Medicine II at the Medical Center—University of Freiburg.

sfb1160.uni-freiburg.de/new...

Nature Medicine. Research Paper:

nature.com/articles/s41591-...

[2greys]

"Reasons to be cheerful, one, two , three." (Ian Drury)

I have said it, Dr John Campbell has said it, now the research proves it!

[Badbessie]

If anything forget the vaccines, yes they have a role but this is the game changer. Covid may linger but this paper gives promise that it will never be the danger it once was. I was happy with with the news of the vaccines but there was always a question concerning a lasting response. Lol I may have a celebration Brandy! My first this year.

[2greys in reply to Badbessie]

I think I will be joining you. I have an almost full bottle of Remy Martin :). It will be my first this year as well, cheers.

[sassy59]

Good news at last. Hurrah for the T-cells! Xxxx

[2greys]

Again interesting, but from 18th August.

Quote "Otherwise, the duration of SARS-CoV-2−specific IgG persistence in serum is far from clear, and we have much to learn about the CD4+ and CD8+ T cell responses."

The above Nature Medicine link is from yesterday, 3 moths later, and answers the question of duration ie. the duration of the immunity is probably as long a for influenza T-cells which have been seen to have the same structure, those influenza T-cells are proven to be very long lasting ie over 80 years. SARS-COV-1 T-cell immunity is proven to be lasting for over the 17 years, since it emerged in 2003, those T-cells give immunity to SARS-COV-2. Very strong evidence that will be extremely hard to dispute.

My partner has been exposed to SARS-COV-2 so many times, with her work, that it cannot be counted, neither of us have had any symptoms since April when we were first infected. She was tested positive for antibodies prior to donating convalescent plasma. By inference I was the same, but excluded from donating because of being a cancer patient. From personal experience and that Nature Medicine link, I am in no doubt whatsoever that the immunity is very real, now confirmed by science.

[Patk1]

Im a member of a longhaul covid group and very many people are indeed getting reinfected,just not being reported.the gd thing is that most arent getting symptoms as bad as last time

[2greys in reply to Patk1]

There is a percentage of people who have compromised immune systems, or immunodeficient, so it is not impossible. Long Covid is still not fully understood yet. I do not think that it is related re-infection or to being immune compromised, personal experience tells me that.

[Patk1]

I was born immundeficient,they eventually discovered last year,so ill be 1st in queue for vaccine thats geared to me.ive not recovered to pre mar/april infection with covid.nearly killed me,so i hope not to get again.im a million x betta than then,but far from right.there are people testing + again every day,but altho have symptoms,theyre not as bad as last time so as u say,immunity must be playing its part 2nd time roundThanku for articles u share 2greys

[2greys in reply to Patk1]

It appears you may be in luck.

bbc.co.uk/news/health-55022288

[2greys in reply to Patk1]

I have just heard that it is £450 per dose!