Vav3 Mediates Pseudomonas Aeruginosa Adhesion to the Cystic Fibrosis Airway Epithelium.

[2greys]

Cystic fibrosis is characterized by chronicsinopulmonaryPseudomonasaeruginosa(Pa) infection. Badaoui et al.describe a pathway promoting luminalfibronectin deposition and apical activityofb1 integrin. This ectopic complex leadsto increasedPaadhesion to the CFepithelium, a mechanism prevented bytargeting the GTP exchange factor Vav3

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Bedtime reading sorted, then 😉 Thanks as always 2greys