Targeted lung denervation

[mophead1960]

Hi, was wondering if anyone has had TLD a new research trial at the royal Brompton hospital london for empysema?

[mophead1960]

Sorry empysema and copd..

[diesel12]

I haven't but I'm not sure if anyone else has. I did read an article about it and it sounds very interesting.

[Billiejean_2]

Hi Mophead, I haven't heard of it and would love to hear some more details, please.

[PastMeBest in reply to Billiejean_2]

Hi Billiejean_2 more info at link below.

dailymail.co.uk/health/arti...

Regards. John

[Billiejean_2 in reply to PastMeBest]

Thanks John !

[PastMeBest]

Hi mophead1960 the following may be of interest to you.

(Sun, 10 July 2016) PastMeBest

Hi falconcottage1 as Toci says one of our members Gilly2235 recently posted about receiving Lung Denervation Treatment.

An article was also published in the Daily Mail and can be seen at the link below.

dailymail.co.uk/health/arti...

Regards. John

[mophead1960]

Hi all, thanks for your replies, I have had TLD but was curious to speak to others who have also had it. I've read the article in the paper & have spoken to the lady involved. Thanks hope you all have a good day x

[Jancon in reply to mophead1960]

How did you find this and how has it left you. Would be really interested

to know. Many thanks and have a good day x

[mophead1960 in reply to Jancon]

Hi, the criteria is very strict but if you meet it go for it! I've had good & bad days since so it's a bit early to say wether it has been a complete success, but no regrets so far!

[jackdup in reply to mophead1960]

Did you have spirometry or PFT both before and after and if so how much did your FEV1 improve?

When you mention good and bad days, is this typical of what you experienced before the procedure and if so are the bad days less bad and the good days better than prior to the procedure.

You mentioned the criteria is very strict so wondered if you can share exactly what they are looking for or what they find acceptable to be given the procedure.

I think most people here would really appreciate any information you are willing to share as far as changes in your condition following the procedure.

Thank you

[mophead1960 in reply to jackdup]

Hi well like I said its early days & unfortunately I had a post procedure chest infection sinusitis & a cold, so consequently my one month follow up showed my FEV1 slightly lower than pre procedure....but one has to be positive & also everyone is different & what may work for one might not necessarily work for another. I'm 56 years old & would try anything to help my condition improve. I will keep you updated with my progress...never give up hope! X

[mophead1960 in reply to mophead1960]

Ps if you go to the royal Brompton web page & look under research it will show the TLD criteria & there's also a phone number to call....good luck x

[Brendabree in reply to mophead1960]

Hello. I have spoken to Dr Karthi at Brompton and asked to be considered for TLD. He asked for Lung function test results and latest from specialist, which were sent to him. He said screening would be very soon. That was six weeks ago. Did it take as long for you to get an appointment?

[mophead1960 in reply to Brendabree]

Hi, I think it was a couple of months before I got an appointment. I would ring again, I rang a few times. Good luck let me know how you get on 😃

[jackdup in reply to mophead1960]

Thank you for the prompt response. Have you found an improvement in your breathing, at least before the chest infection? Can I ask what stage of COPD you have?

Thanks again for posting, and for your response and look forward to updates once you have gotten over your current infection, and I hope it is successful in improving your quality of life.

[mophead1960 in reply to jackdup]

Thanks & seriously I have never questioned what stage CODP I am...I think it's because I have been in denial for a while & have only just accepted my condition...as for breathing the first week I had the procedure I felt amazing-thought here I come London marathon THEN...the chest infection etc etc but like I said NEVER give up hope! X

[sarcoid1234]

The Daly Mail article says it is the latest hope for those with chronic obstructive pulmonary disease (COPD) – an umbrella term for conditions causing lung damage, including chronic bronchitis and emphysema

.

[Peteybob]

It's a bit of a read: Clinical Trials open to many countries.

D0142: Targeted Lung Denervation for Patients With Moderate to Severe COPD (AIRFLOW-1)

This study is designed to answer whether a new treatment called vagal nerve denervation improves lung function, symptoms and quality of life in patients with COPD. COPD is often treated with inhalers which work blocking the actions of the vagal nerve but only temporarily. In this study the vagal nerve in the airways will be denervated permanently to see if it improves patient outcomes. The study is divided into two Phases; in Phase A, participants will be randomised to one of two different energy levels to determine the optimal dose for vagal denervation in the airway; in Phase B, participants will be randomised to receive either the optimal dose from Phase A or a sham-control procedure.

Participants at Royal Brompton Hospital will have Chronic obstructive pulmonary disease (COPD). Following the procedure, participants will be asked to make up to 8 visits in the first 6 or 7 months and then 3 more visits at yearly intervals.

RB&HFT Lead: Dr Pallav Shah

(rbht.nhs.uk/healthprofessio...

Questions? Contact: Dr Justin Garner on 0207 351 8029 (mailto:[e-mail])

Or click on the link for more information about this study clinicaltrials.gov/show/NCT... (scroll half way down for eligibility)