xolair

[geopa]

what is it who can benifit,is it available in uk

[TuckBox2]

I have been on 4 Xolair jabs every 4 weeks for 2 and a half years now.

Since I have been on it I have stopped having nebulisers (4 a day) I stopped taking Uniphyllin tablets, I had a couple of exacerbations after I started but they were not as bad as previous ones, I wasn't hospitalised, just prednisolone & antibiotics.

My peak flows and spirometry have gone up to good levels.

I have not had any bad exacerbations or days off work for the last 18 months.

I hope you get the same results, you normally have to wait at the hospital for 2 hours after your 1st dose of Xolair, after that you normally have to wait about 20 minutes just to check there is no reactions.

I have had no reactions with my other meds for blood pressure and acid reflux

[meglou in reply to TuckBox2]

Hi is xolair available in UK and is it used to help people with copd?

[TuckBox2 in reply to meglou]

Yes it is available in UK but at the moment they are using it for allergic asthma.

[Hidden]

What does it do?

[TuckBox2 in reply to Hidden]

What is XOLAIR?

XOLAIR® (omalizumab) for subcutaneous use is an injectable prescription medicine used to treat adults and children 12 years of age and older with:

•moderate to severe persistent asthma whose asthma symptoms are not controlled by asthma medicines called inhaled corticosteroids. A skin or blood test is performed to see if you have allergies to year-round allergens.

•chronic idiopathic urticaria (CIU; chronic hives without a known cause) who continue to have hives that are not controlled by H1 antihistamine treatment.

XOLAIR is not used to treat other allergic conditions, other forms of urticaria, acute bronchospasm or status asthmaticus.

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about XOLAIR?

A severe allergic reaction called anaphylaxis can happen when you receive XOLAIR. The reaction can occur after the first dose, or after many doses. It may also occur right after a XOLAIR injection or days later. Anaphylaxis is a life-threatening condition and can lead to death. Go to the nearest emergency room right away if you have any of these symptoms of an allergic reaction:

•wheezing, shortness of breath, cough, chest tightness, or trouble breathing

•low blood pressure, dizziness, fainting, rapid or weak heartbeat, anxiety, or feeling of "impending doom"

•flushing, itching, hives, or feeling warm

•swelling of the throat or tongue, throat tightness, hoarse voice, or trouble swallowing

Your healthcare provider will monitor you closely for symptoms of an allergic reaction while you are receiving XOLAIR and for a period of time after your injection. Your healthcare provider should talk to you about getting medical treatment if you have symptoms of an allergic reaction after leaving the healthcare provider's office or treatment center.

Do not receive XOLAIR if you are allergic to omalizumab or any of the ingredients in XOLAIR.

Before receiving XOLAIR, tell your healthcare provider about all of your medical conditions, including if you:

•have any other allergies (such as food allergy or seasonal allergies)

•have sudden breathing problems (bronchospasm)

•have ever had a severe allergic reaction called anaphylaxis

•have or have had a parasitic infection

•have or have had cancer

•are pregnant or plan to become pregnant. It is not known if XOLAIR may harm your unborn baby.

•if you become pregnant while taking XOLAIR, talk to your healthcare provider about registering with the XOLAIR Pregnancy Registry. You can get more information and register by calling 1-866-4XOLAIR (1-866-496-5247) or visit XOLAIRpregnancyregistry.com.

•are breastfeeding or plan to breastfeed. It is not known if XOLAIR passes into your breast milk.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, or herbal supplements.

How should I receive Xolair?

•Xolair should be given by your healthcare provider, in a healthcare setting.

•Xolair is given in 1 or more injections under the skin (subcutaneous), 1 time every 2 or 4 weeks.

•In asthma patients, a blood test for a substance called IgE must be performed prior to starting Xolair to determine the appropriate dose and dosing frequency. In patients with chronic hives, a blood test is not necessary to determine the dose or dosing frequency.

•Do not decrease or stop taking any of your other asthma or hive medicine unless your healthcare providers tell you to.

•You may not see improvement in your symptoms right away after Xolair treatment.

What are the possible side effects of XOLAIR?

XOLAIR may cause serious side effects, including:

•See, "What is the most important information I should know about XOLAIR" regarding the risk of anaphylaxis.

•Cancer. People who receive treatment with XOLAIR may have a higher chance for getting certain types of cancer.

•Fever, muscle aches, and rash. Some people who take XOLAIR get these symptoms 1 to 5 days after receiving a XOLAIR injection. If you have any of these symptoms, tell your healthcare provider.

•Parasitic infection. Some people who are at a high risk for parasite (worm) infections, get a parasite infection after receiving XOLAIR. Your healthcare provider can test your stool to check if you have a parasite infection.

•Some people who receive XOLAIR have had chest pain, heart attack, blood clots in the lungs or legs, or temporary symptoms of weakness on one side of the body, slurred speech, or altered vision. It is not known whether this is caused by Xolair.

The most common side effects of XOLAIR:

•In people with asthma: pain especially in your arms and legs, dizziness, feeling tired, skin rash, bone fractures, and pain or discomfort of your ears.

•In people with chronic idiopathic urticaria: nausea, headaches, swelling of the inside of your nose, throat or sinuses, cough, joint pain, and upper respiratory tract infection.

These are not all the possible side effects of XOLAIR. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at (800) FDA-1088 or fda.gov/medwatch. You may also report side effects to Genentech at [phone] or Novartis Pharmaceuticals Corporation at 888-669-6682.

Please see full Prescribing Information, including Medication Guide for additional important safety information.

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