What’s after Xolair

[wheezy01]

Hello,

I have been on xolair since last September, I’ve got it through a clinical trial. It hasn’t worked at all, I’m still on it because part of the trail is about finding out why it doesn’t work for some people. I was wondering if any of you have any ideas of what might be next to try or if any of you have been in a situation. I’m due to come off xolair in September (thank god)

[TuckBox2]

Hi Wheezy

I too was on Omalizumab (Xolair) for 4 years, I used to have 4x injections every 4 weeks it was helping me for the first 2 years, then it seemed to become less effective after I had a bout of pneumonia.

I was swapped over to Mepolizumab (Nucala) in May 2017, I have had no ill effects from the injections, I have only had 1 bad day with my asthma I was coughing a lot more than usual and my wife said I should go to the doctor. I had an asthma attack in the GP surgery, he called for an ambulance and I had 2x nebs in the ambulance, by the time I got to A&E my breathing etc had settled down, I was given abs but no steroids. I had 5 days of abs & pred over xmas due to a chest infection, this is normally my bad time anyway and I usually have 4 or 5 A&E visits over the winter period.

At my March visit for my jab (only 1 injection with Mepolizumab) I was told they will be keeping me on it as it seems to be keeping me out of hospital and off the preds.

I was also put on Fostair 200/6 October 16, that seems to have helped improve my peak flows I am 500+ 3-4 days a week, rather than once every month or two.

[Jenzzie18]

Hi

I was on xolair from feb 2017-feb 2018. It seemed to work a little for about 6 moths then stopped so I was taken off it back in feb. I have to say I haven’t noticed and difference not being on it now. I’m not sure what comes next as this is exactly what I’m waiting for myself. I am being referred to the Brompton so I’m hoping they may have some answers especially as I’m up to 5 hospital admissions so far this year. If I hear anything more on the what’s next front I will let you know.