I hade an aortic valve replacement in 2019. Been on Warfarin since then, and not able to drink any form of alcohol. I get face/chest flush, face swell, hives all over my body and in every way a Disulfiram-like effect.
Has anyone had the same? Really took away some of my life quality. I want to be able to enjoy a beer or a glass of wine sometimes.
I tried to fina answer to this and my theory is that Warfarin interfere with the enzyme ALDH2, like Disulfiram does. I think Warfarin inhibit ALDH2. That can also cause some other things to be aware of, like an increased risk for throut cancer, IF i am right. Does anyone else know if Warfarin can cause ALDH2 defficiency?
Is there any cure? Is it reversible if you stop Warfarin?
If you are not dealing with a Metal valve ask your GP/Consultant to try you on rivaroxaban? HTH
Can't regain any form of fitness
Is it possible to re-clot while on meds. How to get it checked?
Apixaban for Pulmonary Embolism 
No-oo, but I went completely off red wine when they put me on rivaroxaban. This may just be a function of ageing, though. When I mentioned it to the consultant, he roared with laughter and said he hadn't come across that particular side-effect before. But it's worth checking with your haematology team next time you go in for a blood sample, just in case it's something reversible. It may be Just One Of Those Things, and you'll have to stay sober from now on.