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rapid weight gain

Afib_girl profile image
26 Replies

anyone else have rapid weight gain on metoprolol or Eliquis? I have been on medication for 6 months and have gained 15 lbs. so far. I exercise regularly (run, spin, elliptical rower etc) talking 4/5 days a week… I am still rapidly gaining. I don’t eat poorly or any excess sweets. I’m very frustrated. I’m over weight to begin with so 15 lbs right is a lot.

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Afib_girl profile image
Afib_girl
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26 Replies
BobD profile image
BobDVolunteer

Unlikely to be the anticoagulant but beta blockers are often blamed for weight gain.

jeanjeannie50 profile image
jeanjeannie50

What dose of Metoprolol are you taking and have you felt more tired since taking it?

Jean

Afib_girl profile image
Afib_girl in reply tojeanjeannie50

50mg once a day

jeanjeannie50 profile image
jeanjeannie50 in reply toAfib_girl

Do you feel more tired since starting to take it?

Afib_girl profile image
Afib_girl in reply tojeanjeannie50

Yes I always seem to fall asleep in the afternoon wo meaning to.

jeanjeannie50 profile image
jeanjeannie50 in reply toAfib_girl

It's certainly sounding like it could be the tablet. Have you ever had your thyroid hormone levels checked? This could be another reason for your tiredness. I used to sleep afternoons too until I discovered that mine was underactive. I also had a gallbladder problem and because of this cut all fat out of my diet (I had pain if I didn't) and over a year lost a stone in weight. Of course having AF is certainly a reason for feeling tired. Has your weight only gone on since being diagnosed?

Jean

Jean

Afib_girl profile image
Afib_girl in reply tojeanjeannie50

I’ve had my thyroid check multiple times… I have been stable in my weight for years this is suddenly gaining 15 lbs since Jan.

doodle68 profile image
doodle68

Hi Afib girl :-) I actually lost 1.5 stone when striating Eliquis and a beta blocker, the shock of diagnosis of AF and the prospect of a life time of medication made me make a permeant change my lifestyle and that include reducing my food consumption.

I don't drink alcohol now, it is empty calories (except home made Kombucha which contains a tiny amount of alcohol ) made I am most of the time vegetarian, I eat my main meal at lunchtime so I am active after my main meal not sitting around and I don't eat or drink anything after 5pm until breakfast time except water.

mav7 profile image
mav7

I have gained about 10lbs over the past year on Metoprolol and Eliquis but also attribute that to reduction in exercise.

If you are exercising regularly, look at your diet and possibly changing your exercise regiment without over doing it.

And of course, consult with your doctor. Being at a healthy weight is an important AFib deterrent.

Squidgybod profile image
Squidgybod

I put on 21 lbs in 21 days when I was put on Rivaroxaban (Xarelto). The extra weight was caused by water retention in my subcutaneous fat. Rivaroxaban has a reputation for weight gain which is difficult to reverse. I haven't had any problem with Eliquis so far. I've been on it 6 weeks.

Ppiman profile image
Ppiman

There was one study I read that showed that metoprolol seemed to be the culprit, but rapid weight gain is, I should think, mostly caused by fluid retention since fat must surely takes quite a while to form. You might ask your doctor about this, perhaps?

Otherwise, you could try methodically eating slightly smaller portions of everything for a couple of weeks and see if some weight loss results. If it does, then it is not fluid but calorie intake.

Steve

JOY2THEWORLD49 profile image
JOY2THEWORLD49

HiCould be the metropolol.

With fatigue and no energy I hated the med and got off it, made me breathless.

NZ are changing their minds about A.F and now use Bisoprolol.

I gained .5 kilo. But I knew I shouldnt be there.

Now on CCB Diltiazem 120mg CONTROLLED.

cheers JOY 73. (NZ)

RoyMacDonald profile image
RoyMacDonald

Slight weight loss on Eliquis, but I am cycling a lot and very hard, putting out 189 watts average for well over an hour. It's very hilly locally.

All the best.

Roy

stargazer52 profile image
stargazer52 in reply toRoyMacDonald

I’ve found with larger dose of bisoprolol I’m very breathless very fatigued and feel terrible, yet basically been told I have to live with it!!!

RoyMacDonald profile image
RoyMacDonald in reply tostargazer52

Well it's always your choice what to do. I started off on Bisoprolol but did not like it so I stopped taking it with my consultants consent.

All the best.

Roy

Ducky2003 profile image
Ducky2003 in reply toRoyMacDonald

Same here. Bisoprolol made me feel dreadful so I begged my consultant to put me on Diltiazem instead, which he did.

Ducky2003 profile image
Ducky2003 in reply tostargazer52

I would query other meds. I did and was put on Diltiazem instead and felt instantly better.

Auriculaire profile image
Auriculaire

I have read lots of posts on drug evaluation sites from people complaining about weight gain on Eliquis. It is more likely to be the beta blocker though. Someone posted here that beta blockers interfere with the conversion of T4 to T3 which would slow the metabolism. If you are following the same diet and taking the same amount of exercise as before starting the meds then I think the finger points at them.

stargazer52 profile image
stargazer52

I didn’t put weight in with apixaban but in last 2 months have had bisoprolol increased from 1.5mg to 7.5. I’m still not out of a fib but have put on 7kg with no change in my diet. Was told it was water retention. I’m waiting on diuretic s to try and reduce it.

shiftcolors profile image
shiftcolors

I’ve gained 40 pounds on Metoprolol and now it’s also causing tiredness and a cough.

Afib_girl profile image
Afib_girl in reply toshiftcolors

Did the cougar start right away? I just developed a cough but I have been on metoprolol for 7 months. Gained 15 lbs and going

shiftcolors profile image
shiftcolors in reply toAfib_girl

My cough did not start right away. Several months to develop. Weight gain started pretty quickly however. At first I thought that was my thyroid meds but it was not.

DawnTX profile image
DawnTX

Hi. I am not sure what medicine was doing it but I was on metropolol and Multaq I am now off of both and the weight is sliding off again. I have never been a Barbie doll but last October I was really happy with where I had gotten to and it was easy. Then I moved to Texas and had a crazy life going on. I didn’t think I was eating bad but my clothes got tighter and tighter and I ended up gaining 40 pounds. I have been beside myself with this because no matter what I tried it would not budge. For every med that helps us there seem to be side effects that are negative to us. Hang in there and hopefully he will be allowed to stop taking your meds eventually and the weight will drop again. It’s so frustrating when we try to do the best we can and get nowhere. Best of luck.

Beta blockers have this issue but they seem to want to pretend they don’t. I didn’t have weight gain on the atenolol, but just prior to starting it I had lost quite a bit of weight, and I have more to go and it had been near impossible to take any more off. I now am finally seeing some budge after weaning myself of the beta blocker.

BobbyGee profile image
BobbyGee

doodle68's disciplined diet sounds very sensible. I've put on weight gradually since being diagnosed with Afib, and I have to take Eliquis and Bisoprolol. In my inexpert opinion, excess weight contributes to the Afib condition.

Nigel2000 profile image
Nigel2000

Beta-blockers really hit me hard. Weight was NEVER an issue for me before I started treating the afib. It’s hard, I think, for working people who like to be active to decrease calories enough to compensate for the lower metabolism AND exercising through the fatigue and breathlessness was extra hard. I had to stop them except for the pill in the pocket. But then I had a stroke and then dofetilide and then 2 ablations. Still on dofetilide, eliquis and a statin. I feel much better now but still can’t shift the weight. It’s WAY better to be a bit heavy than to have symptomatic afib and way better than having another stroke. But I do mourn the cost of health to my vanity.

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