Itchy skin and hives with Xarelto

[Jill13]

Has anyone else experienced itchy skin or hives whilst on Xarelto? It is listed as one of the side effects of most anticoagulants.

[Dawsonmackay]

I've been taking Xarelto for three years and on occasion I do have itchy skin, mostly in the area on my right rib side. When I apply lotion, it goes away.

[Jill13 in reply to Dawsonmackay]

Thank you for your comment. Mine is like hives and very itchy and creams don’t help really.

[Tapanac in reply to Dawsonmackay]

I was on Rivaroxaban and had some itchy skin and now on Apixaban and still the same. I blame mine on old age (76), but I cream etc and not so bad. Mostly on my legs. Hope yours goes away soon. Best wishes

[Ticktoc in reply to Tapanac]

Itchy skin on right side and legs on Apixaban worse at night if I get to hot drives me mad at times used itchy skin cream and dr prescribed antihistamines still get it some days worse than others but have had similar with Atorvastatin

[Jill13 in reply to Tapanac]

Thanks for reply

[Jill13 in reply to Dawsonmackay]

Thanks for reply - mine is worse at night.

[Auriculaire]

I have this on Apixaban but I have had it in the past before taking an anticoagulant. Always in winter. It can be due to dry skin . Before it was I think due to my hypothyroidism which can cause dry skin. My thyroid meds need to be put up at the moment but with the afib I am having to do this very very slowly. I find Benadryl cream or Eurax cream calm the hives. I don't like taking antihistamines as even the non drowsy ones make me drowsy ! But they do work to take away the hives.

[Jill13 in reply to Auriculaire]

Sounds like a change of anticoags may not help. Thanks for reply

[Hidden]

Yes I'm on this medication and I get a lot of itching, however, I wasn't sure if it was the xarelto or not I've been cutting down a bit to check but not much change so I've not come to any conclusion yet.

[Jill13 in reply to Hidden]

I’m not sure either but will ask for a change and see what happens Thanks for reply

[Opoho]

I changed from Xarelto to Eliquis after episodes of hives and angioedema. I’m also on a 6 week course of antihistamines at present. GP prescribed some mild cortisone cream which helped the itching. Good luck!

[Jill13]

Thank you. Antihistamines don’t seem to work anymore but I will ask my doctor to change me over to Elquis and see if that works. The only relief is if I take a prednizone tablet and that takes hives and angioedema away for 24 hours

[YidBee2020]

My itching started on holiday (Jan 2020) so could have been the Columbian heat that brought it on. I am taking Xarelto (Rivarboxaban) and have been since Nov 2019. No itching at the start but now I get intense itching on stomach, legs, lower back and arms. Worst at night . I have tried E45, betnovate and Elocon none seem to help. I take 50mg of Difenhidramina at night and that helps a little with sleep. Going to a dermatologist for a biopsy next.

[Jill13]

Thanks for reply. I have to take a prednisone ( prescribed by GP ) when really bad as nothing else seems to work would be interested to hear what your dermatologist said. I went to one last year, had all sorts of tests which were inconclusive.

[YidBee2020]

I will update once I get results back in a few weeks. I also requested extensive blood tests to check for liver, thyroid, kidney and blood over-clotting deficiencies. GP seemed supportive to identify the issue.

[Jill13]

Thanks