Xarelto and Liver Issues

[KateeKittee]

Has anyone developed liver issues since beginning Xarelto?

[BobD Volunteer]

You are supposed to have liver function tests at three and six months and therafter anually if you are on rivaroxaban . This should pick up any problems. It seems that some GPs here in UK are not aware of this.

[Jjda in reply to BobD]

I think that is also true of Elquis, but my EP did not order any liver tests. The US doctors are also apparently not aware of this. I had my annual with my GP and he did them, as he always does, but that was after I had been on Eliquis for a year.

[10gingercats in reply to Jjda]

Same here. I am on Apixaban and have a fairly attentive GP. However, I always have to remind him about general blood and liver funtion tests.It is usually yearly.

[healme in reply to Jjda]

Me too

[Flo2pen in reply to BobD]

Hello did not know this was a necessity. I have been on xarelto for almost a year. Who checks liver GP, Pulmonologist or Cardiologist?

[BobD Volunteer in reply to Flo2pen]

I posted this recently having been advised of NICE guidelines by the office.GP should do these tests as a matter of course.

[Finvola]

I have some raised enzyme and lowered calcium levels recently. I started Apixaban over 5 years ago. I feel fine but it shows the importance of proper liver and kidney screening for those of us taking any of the DOACs

[Jjda in reply to Finvola]

Are they doing anything about the results, or just watching it over time?

[Finvola in reply to Jjda]

So far, just retesting after a couple of weeks on calcium tabs.

[pusillanimous in reply to Finvola]

I have been on Xarelto for 3 years and have regular full blood tests, on my most recent one a couple of months ago,my GP described my liver function as like a teenagers, all my results as beautiful and my Cardio described them as pristine. I had a compression fracture of a vertebra about 18 months ago . due to some osteoporosis and osteopenia, and was immediately put onto Boniva and Calciferol, a - calcium and Vitamin D combination, and I wonder if those tablets protect the liver.

[Bagrat]

I had raised alk phosphatase on annual check ( on apixaban). I had to ask for check. Had renal function when I started it but not Liver function as far as I could see so no base line. Repeated after one month then three months. Slightly lower. Am expecting another test August but may have to remind!!

[CDreamer]

A friend of mine developed elevated liver enzymes - but it turned out she wasn’t taking Rivaroxaban with a substantial meal containing protein and fat. She changed the time she took the tablet to when she had her main meal and had no further problems - another thing the doctors don’t tell you!

I have monthly bloods for liver & kidney but it is more normal to have 6 monthly checks. Our GP practice is outstanding and ring and text me if I haven’t made my next appointment and are meticulous about regular bloods believing that regular monitoring means they pick up on early indicators, reducing their work load as often the nurses deal with any anomalies.

[Flo2pen in reply to CDreamer]

Would hope that they are as meticulous like that here in the US. But its sad when you dont know what to ask so you could be in the "Know".. So then it may be best to take xarelto with a meal am thinking?? will def try that way,

[vettman454 in reply to Flo2pen]

My cardiologist said its important to take with food. Since breakfast is my most regular and substantial meal I take it then. At least three years now. Annual blood tests. Everything is fine.

[Ladypaula]

I've been on Xarelto for 2 years now and no problems with my liver Have periodically had blood tests for liver function .

[KateeKittee]

You are correct about not monitoring yearly in the US.....I was remiss in not have blood work for two years and it showed up. Was diagnosed with fatty liver and am seeing a hepatologist. I was not obese, was active and ate a healthy diet.........Also had Lyme before the AFib diagnosis. I think it is connected.

[Flo2pen in reply to KateeKittee]

I agree with you. How are you feeling? and how often now do you check your blood levels or kidney/liver functions. I am in the care of an endocrinologist here in TX so now I know to ask to get these things checked. Also to check on my INR levels as well, because I have DVT from having heart failure