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Apixaban and Piles plus a few other things

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A spinal dural arteriovenous fistula was badly managed by my surgeon twice(!) leaving me in permanent urinary retention and a non functioning lower bowel. This was followed by a tethered spinal cord which took two goes to untether (the second op surgical mismanagement as the surgeon would not listen to me saying I was still tethered as the symptoms recurred almost immediately after the first operation. it took further year to get finally completely untethered elsewhere by which time my legs have tightened up so much the pain is excruciating and I am almost wheelchair bound. We tried bowel irrigation over two years but that ultimately failed so in December I had a Colostomy which is the only success story to date.

Immediately after the colostomy I became aware of pain in the rectal area down to piles (internal and external (big ones).

I am on finasteride, Tamsulosin for prostate and Diltiazem for BP. All enhance the effects of apixaban. I'm taking valium and paracetamol for the leg pain as well which doesn't impact apixaban.

I'm also taking Ciprofloxacin for a UTI that started last Sunday which seems to be clearing which I'm taking after the apixaban, which I have started taking before the Diltiazem to try to mitigate the effects and spread the other drugs over time for the the same reason.

I'm now 2 and a bit weeks post piles op but the pain hasn't resolved very much and its also impacting my legs badly. I'm still getting some slight bleeding and My GP has said recovery will take 4-6 weeks..

Has anyone had any experience of being on apixaban and needing a moderate piles op that can give an idea of how long I will have to wait to see the swelling and inflammation go down which may help relieve some of the leg pain and make things bearable? I understand the bleeding (which is slight) will ease over time.

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Auriculaire profile image
Auriculaire

You are risking a worsening of your leg pain with the Cipro. This is no longer recommended for UTI unless no other antibiotic can be used as the risks of severe reaction outweigh the benefits. The EMA ruled on this in March and all GPs should have received a letter to that effect from MHRA. Cipro can cause tendonitis and neuropathy and leg tendons are often affected.

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