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Took double dose of Apixaban and Flecainide

Finvola profile image
80 Replies

My 'foolproof' drug-taking regime broke down this morning and I took 5mg Apixaban and 100mg Flecainide twice within a couple of hours. Realised almost immediately what I had done and did the fingers down the throat over the loo manoeuvre - to no avail.

Rang pharmacist and got the expected advice - miss tonight's doses and be aware of heart rate and rhythm, without overthinking it and that I hadn't exceeded the daily maximum of 300mg.

Even so, I'm concerned about the Flecainide and wondered if anyone else has taken too much in one go and how it affected their heart (if at all). Just when things were going so well . . . .

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Finvola
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80 Replies

Dunno is the honest answer regarding Flecainide but pretend you took it as a PiP and I’m sure you will be OK. Regarding Apixaban, it does not cause spontaneous bleeds so wrap yourself up in cotton wool and stay in bed (figuratively speaking of course) 😉

Finvola profile image
Finvola in reply to

Thanks FlapJack - that's a good thought about the Flec being a PIP.

mjames1 profile image
mjames1

Your pharmacist's advice seems sound. You are still under the daily limit for the Flecainide. Skipping your evening dose of Apixiban should put things back to normal by tomorrow. I would just be a little more careful, activity wise today. Happens to all of us. Last time it happened to me I got an AM/PM pill box.

Jim

Barbara72 profile image
Barbara72 in reply to mjames1

I have double dosed in the past with no adverse reactions, but not with those specific meds. Just wanted to say hello and wave at you across the bay.

Always think about you en route to my grandchildren’s riding lessons and wave a cheery hello in the vague direction of your mountain home! 😀

Hope your day is uneventful.

mjames1 profile image
mjames1 in reply to Barbara72

Hi, was this post addressed to me, or someone else? Don't think we know each other, I'm in the US :)

Jim

Barbara72 profile image
Barbara72 in reply to mjames1

sorry, was to Fincola. Posted in the wrong space. Mea Culpa!

mjames1 profile image
mjames1 in reply to Barbara72

I can always use a wave, so next time maybe one toward the colonies :)

Jim

P0rtnahapp1e profile image
P0rtnahapp1e in reply to mjames1

Actually, we are on the north coast of Ireland on the Atlantic Ocean, so if you’re on the east coast you may well see a wave from here, if only the watery kind! 🤣

Nannysue1 profile image
Nannysue1 in reply to P0rtnahapp1e

Well I must be a neighbour for the next few days then. I'm over here for the second time thus year, trying to track some relatives down.

Barbara72 profile image
Barbara72 in reply to Nannysue1

What part? Any surnames or tow lands?

Nannysue1 profile image
Nannysue1 in reply to Barbara72

Hi Barbara. Maiden name Totten and we think from the Belfast area. Tandragee,Ahgalee, Armagh, areas we think

Barbara72 profile image
Barbara72 in reply to Nannysue1

Sorry, don’t know anyone in those areas and no one called Totten. Was hoping it would be nearer to us and we’d end up as 2nd cousins!

Have you tried DNA? We’ve found relations through Ancestry.

Good luck!

Nannysue1 profile image
Nannysue1 in reply to Barbara72

Well you're the first person over here who hasnt told me that they dont know a Totten! Seems like a really common name over here unlike in England where I've never come across one. Yes done Ancestry DNA and found lots in my other lines but none from my paternal grandfathers that I can link. Off to Roots Ireland today 🤞

Finvola profile image
Finvola in reply to Nannysue1

Welcome to Ireland Nannysue - the emerald isle is looking slightly burnt at the moment. Have you tried a search at the Public Records Office or a register of ratepayers? Totten is not a common name here so it might be an easy search. Best wishes.

Nannysue1 profile image
Nannysue1 in reply to Finvola

Hi there thanks. Yes going back to records office in belfast tomorrow . We were over there a couple of months ago but we have different info now. Just thinking, I've gone completely off piste with my non related heart topic ( though it's very dear to my heart) apologies to all.

Finvola profile image
Finvola in reply to Barbara72

Well - hello Barbara72 (name change?). I was thinking about you on and off over the last couple of years and wondering how you are. Will wave back when I think you are passing by.

Here's to nothing happening! Nice to hear from you.

Finvola profile image
Finvola in reply to mjames1

Thanks Jim - the busiest I plan to be is turning pages in my book - and I'll probably get a daily pill box too.

Tapanac profile image
Tapanac in reply to Finvola

they do a really good dosset box on Amazon and big enough to take all our pills. If I knew how to do it I would copy and paste it on to you but am duh with technology

X

Finvola profile image
Finvola in reply to Tapanac

Thanks Tapanac. I ordered the Cartee Weekly Pill Box Organiser from Amazon to try it out.

pottypete1 profile image
pottypete1

I can relate this to the many times I have taken extra Flecainide as PIP totalling the daily maximum including my twice daily 100mg Flecainide

It made me feel heavy and nauseous for about 24 hours but did resolve my AF problem.

I expect this to make you feel lethargic for about a day but little else to worry about.

Pete

Finvola profile image
Finvola in reply to pottypete1

Thank you Pete for the reassurance . I do feel slightly leaden but we aren't used to heat in N Ireland and last night was oven-like so I haven't slept much!

pottypete1 profile image
pottypete1 in reply to Finvola

”leaden” - that’s the word was looking for 🙂.

Hope you feel OK soon.

Yes the heat is sapping isn’t it.

Pete

Barbara72 profile image
Barbara72

BTW, this is the alter ego of P0rtnahapp1e. Had to re register once when the site wouldn’t let me in so I now have two personas (personae?)

Finvola profile image
Finvola in reply to Barbara72

Yes - I worked that out!

JaneFinn profile image
JaneFinn in reply to Barbara72

Oh hello P0rtnahapp1e!! You can do a Jekyll and Hyde on us with your split personae if you want?? 😄 xx

JaneFinn profile image
JaneFinn

Sorry can’t help but just wanted to say bad luck! So easily done. I took the wrong tablets a few days ago but managed to spit them out before swallowing (very dramatically over the kitchen floor!) so I really sympathise. Jx

Finvola profile image
Finvola in reply to JaneFinn

Thanks Jane - I realised my mistake as the second tablet went down and probably shouldn't have bothered getting to the bathroom!! Good that you evicted them in time.

waveylines profile image
waveylines in reply to Finvola

Very easy to do. Ive done it too but not with the tablets you describe. Checked with pharmacist and no harm done.Enjoy your day of rest. Hugs

Eirecara profile image
Eirecara

Best wishes ☘️x

Finvola profile image
Finvola in reply to Eirecara

Thank you.

jeanjeannie50 profile image
jeanjeannie50

Such an easy thing to do to take a double dose. Please buy yourself a day by day pill box, or even a few of them - think I need another one as well.

How are you feeling now?

Jean

Finvola profile image
Finvola in reply to jeanjeannie50

Thanks Jean - I was sooo sure my system worked - did so for nearly 10 years - but this morning was the morning from hell and I got distracted. Lesson learned and I'll look on Amazon for a pill box after dinner.

I feel fine, thank you for asking - a bit leaden still - but I slept most of the afternoon, taking FlapJack's advice, without the cotton wool, though.

Vonnegut profile image
Vonnegut in reply to Finvola

My Flecainide comes in strips of ten, five sets of two side by side so I can see if I have taken the morning one ( one gap). I keep another strip to use on the odd occasions I may require an extra one as a PIP so I don’t mess up my pattern!

Finvola profile image
Finvola in reply to Vonnegut

I like an ordered pattern too - much less easy to make (another) mistake.

Suesouth profile image
Suesouth

I got two monthly boxes, 1 am and 1pm, marked with the days, after this happened to me, but you are under the maximum dose for flecainide!

Finvola profile image
Finvola in reply to Suesouth

Thanks Sue - I've ordered an AM/PM weekly box from Amazon and it should be here today.

Suesouth profile image
Suesouth in reply to Finvola

great, wouldn’t be without mine now especially with so many tabs to take,

LizLancashire profile image
LizLancashire

I did it a few years ago. I was so engrossed in the book I was reading over breakfast. After ringing the surgery for advice I turned to friends on here for advice and comforting words. All was well and I survived.However the following week I did it again. I was so embarrassed I didn't tell anyone. Rushed upstairs to try and make myself vomit but couldn't. I started to feel really ill. I thought Oh well, I'll lie on sofa and wait to die. Then thought No, I'd better wash up breakfast dishes and leave the kitchen tidy. I went into kitchen and there was second pill on the floor. I had only taken one. 😆

Finvola profile image
Finvola in reply to LizLancashire

😀Aw Liz - sorry I had to laugh at your choices - lie down to die or wash up! I took my morning dose just now and I counted and checked the tablets THREE times. Distraction is the enemy of pill-takers.

LizLancashire profile image
LizLancashire in reply to Finvola

Yes, distracted by book both times. Learned my lesson though. I have am and pm pill box now and concentrate.

irene75359 profile image
irene75359 in reply to LizLancashire

Your post just made me laugh out loud!

LizLancashire profile image
LizLancashire in reply to irene75359

Good, so pleased. We need laughter in our lives.

Lenaropes profile image
Lenaropes in reply to LizLancashire

You just made me giggle. Something I would have done.

LizLancashire profile image
LizLancashire in reply to Lenaropes

I was so happy to see that yellow Edoxaban on the kitchen floor.

Tarikor profile image
Tarikor

as others have said, that is the normal dose for a PIP approach when having an event. So it should be fine. The maximum daily dose for Flecainide is 400mg, so taking 200mg in one go is not a problem if it is a once off. I accidentally took 300mg in one go in the middle of the night when I had a breakthrough AF and found no adverse effects (I normally never take Flecainide). Make sure you take electrolytes (not those sports drinks which are very dangerous for us AFibbers) that contain sodium, potassium and magnesium, in the meantime and rest up, you will be good.

Finvola profile image
Finvola in reply to Tarikor

Thank you Tarikor - that's a good suggestion re electrolytes. I have Dioralyte in the medicine cabinet.

Tarikor profile image
Tarikor in reply to Finvola

Dioralyte is a fantastic electrolyte, just make sure you take the plain flavoured one. All the ones with flavours are really bad and unhealthy. Cheers.

Tapanac profile image
Tapanac

yes I’ve done that with the flecainide and have to say it was ok for me, but everyone is different. If you are still worried perhaps you could ring your GP or your EP/cardiologist’s secretary

All the best

Pat

Finvola profile image
Finvola in reply to Tapanac

Thanks Pat - it's a first for me and I wasn't sure about the effects or if it would destabilise my quiet heart. All is now back to normal.

Tapanac profile image
Tapanac in reply to Finvola

good I’m glad you are back to normal

Sniggetts profile image
Sniggetts

Hi there, I’m a bit neurotic about taking meds am / pm so this would really worry me too, pharmacist advice is great & sure you’ll be fine.

I keep my AM box upstairs by my bed ( take meds as soon as I wake up ) &my PM box downstairs in the kitchen so I don’t open the wrong section as I’m dopey enough to do that ! 😂

Take care , drink plenty & have a relaxing day 😊

Finvola profile image
Finvola in reply to Sniggetts

So true Sniggetts - anything that can possibly go wrong . . . .

I feel back to normal this morning and it's amazing how many of us have had a similar experience.

Ppiman profile image
Ppiman

I was so tired yesterday that I took my evening's tablets in the morning... I survived, and I'm sure you will, too. I was so cross with myself but my lack of sleep and mornings make for an interesting time!

Best wishes

Steve

Finvola profile image
Finvola in reply to Ppiman

Thanks Steve - lack of sleep and a distracting situation didn't help my concentration yesterday either. Take care too.

Ppiman profile image
Ppiman in reply to Finvola

If you ever find a cure for insomnia, pass it on.

Steve

ellamental profile image
ellamental

Hi. I did this with apixaban as well, was half adleep, worried all day but nothing happened luckily. 😊

Finvola profile image
Finvola in reply to ellamental

It's just too easy to do, isn't it?

ellamental profile image
ellamental in reply to Finvola

Yes. I might try the dosset box too. 😊

Vonnegut profile image
Vonnegut

An AF episode once started only 20 minutes after I’d taken my evening Flecainide 100mg so I took another one as a PIP and the episode ended a few hours later and I’m still here!! I stopped taking the anticoagulants as I rarely have episodes on the Flec and they never last more than a couple of hours but even that has messed up my digestion as the anticoagulants did and added to my fatigue! I am going to be involved in a research project into chronic fatigue now which should be interesting.

Finvola profile image
Finvola in reply to Vonnegut

When I realised from other posters that I had taken the equivalent of a PIP, I started to feel more relaxed about my mistake.

Best wishes with your involvement in the research project - it should be and informative and interesting experience.

Vonnegut profile image
Vonnegut in reply to Finvola

Thank you! I spoke to the woman conducting the research this morning and she sounds lovely.

JOY2THEWORLD49 profile image
JOY2THEWORLD49 in reply to Vonnegut

Hi

In Dec last after being CONTROLLED by Diltiazem 120mg AM 2.5mg Bisoprolol PM my H/R Day Still went from 88-96 to now 62-69 till 6pm!

No more stopping during a walk in slightly elevated hill, no excessive sweating or fatigue although I can have a brief nap at the end of day, I believe it is lesser in quantity meals and weight loss first 3kgs now 5-6kgs. always on low fat diet.

cheri jOY. 74. (NZ)

yzmd profile image
yzmd

Ordinarily I would take 100 PIP but one evening in Feb. I took 200 mg. In an hour I felt unease in my stomach and went to the bathroom where I fainted and was on the floor momentarily. Cardiologist then changed my regimen from PIP to 50 mg flecainide daily in am and pm.

Vonnegut profile image
Vonnegut in reply to yzmd

I went on to that when the episodes started increasing and now on 100mg twice a day when a few episodes still occurred. It works except on very rare occasions like when I must have caught covid and the time recently when an episode started about 20 minutes after I’d taken the pm one! Hence another as PIP. Hope the 50mg am and pm works well for you for longer than it did for me!

Dippy22 profile image
Dippy22

I was taking 50mg twice a day and one evening I tried an extra 100mg as a PIP when the AFib had gone on for two days. It gave me the most incredible double vision and I mean incredible and the next day the doc took me off it immediately (didn’t stop the AFib either).

As people have said 300mg is the daily max and you’re within that, so it shouldn’t be a problem. Just watch for any side effects.

Finvola profile image
Finvola in reply to Dippy22

Scary reaction Dippy - so far, Flecainide has been my friend, stopping my AF for 9 years now. Fingers crossed.

Dippy22 profile image
Dippy22 in reply to Finvola

It certainly was! I’ve never experienced double (treble?) vision before and it was surreal.

Hi there, how are you today? I hope that you just rested up and are back on track! I nearly did the same recently, the cardiologists reduced my bisoprolol but I had an old higher-dose tablet lurking in my tablet box somewhere and that second tablet was on my tongue when a brain cell fired and went 'time to spit!'. Easily done... I find my tablet box usually makes things pretty foolproof though, put the daily dose in and voila. Haven't yet found a spot for the flecainide, you are making me think it's a good idea. Take care! Lis xxx

Finvola profile image
Finvola in reply to

Thanks Lis - yes, back to normal today but the temperature here is 26 degrees so I'm still slobbing about, reading and eating! My brain cell was too slow yesterday and I could feel the Apixaban go down smoothly as I realised something was wrong. Got my box just now and have to devise an idiot-proof regime. 😆

in reply to Finvola

Very relieved to hear it! That brain cell we share needs a telling off 😀Boxes are very helpful, I have an alarm too for the new one because it's twice a day and the brain cell can't cope lol

reinaway profile image
reinaway

Your OK Finvola because I used to be on 10mg of Nebivolol and am still here to prove it!! 😅

Finvola profile image
Finvola in reply to reinaway

That's a large dose - mine is 2.5mg.

reinaway profile image
reinaway in reply to Finvola

If you remember several years ago you were the one who recommended Nebivolol to me and I was so glad you did because I was on a high dose of Bisoprolol with awful side effects. Last year I finally went for Pace and Ablate which although taking a while to settle down has been my salvation. However I still take a tiny 2.5 of Nebivolol for my migraine but nothing else and am symptom free. Best wishes to you.

Finvola profile image
Finvola in reply to reinaway

Thank you reinaway.

That's really good news and I do remember our conversation about Nebivolol and the problems which you were experiencing with Bisoprolol. Since then, I've been taking the same dose as you are now and so far, so good.

It means so much to be symptom free - long may it continue. Very best wishes to you too.

Ducky2003 profile image
Ducky2003

My idiot proof method is taking the tablet from the left of the strip in the morning and the right in the evening so I can always tell if I've taken the morning dose. My problem is forgetting to take them first thing rather than the other way around 😁.

Finvola profile image
Finvola in reply to Ducky2003

The best laid plans and all that Ducky. I find that any upset in 'normal' routine usually means I forget but double taking is a new one for me. 🙂

JOY2THEWORLD49 profile image
JOY2THEWORLD49 in reply to Ducky2003

Hi

My safeguard is ripping offstrip TWO. On the bedside table next to glass of water.

I take the PM late at say 10pm. The other stays there so I know I need to take it sometime later AM.

Sometimes it gets late and I have only forgotten if out. After blood test etc.

cheri Joy

JOY2THEWORLD49 profile image
JOY2THEWORLD49

An overdose of your anti-co-agulant is detrimental. Ring for ambulance immediately.

Is your Apixaban taken once or twice a day?

Never take Flecainide.

Just taken PRADAXA at 1.50 pm AM dose. it means I cant take PM dose till

midnight.

Ambulances should have antidotes.

cheri JOY

Finvola profile image
Finvola in reply to JOY2THEWORLD49

Apixaban is unlikely to cause spontaneous bleeding and it has a lower risk of inter-cranial bleed than some other anticoagulants. So, I calculated that my main risk was from accidental injury - knives, gardening etc and caught up on some sleep that afternoon. All was well.

JOY2THEWORLD49 profile image
JOY2THEWORLD49 in reply to Finvola

Hi

I understand that Apixaban is a twice a day med. Some are once and if once is twice then the risk of a bleed is so much greater.

I chose PRADAXA as it was a twice a day med with an anti-co.agulant.

Take care, JOY

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