Moderate risk of interaction - Apixaban and fish oil

Hi Finvola it says ''other products containing omega-3 fatty acid'' I am assuming that doesn't mean O3 rich fish which it is recommended we eat 3 times a week something with which I try to comply.

Dr Gupta frequently suggests a mediterranean diet which is rich in O3.

Doodle - we were just discussing this at dinner! We eat oily fish about three times a week also and it is recommended on practically every AF site you see. Interesting that Eliquis agree with this advice. When i was prescribed Apixaban fish oil was not in the list of things to avoid.

I assume that the reference to moderate interaction may be for large doses which wouldn’t be the case with a piece of salmon or a mackerel but I need to do more reading.

Interested in the original post and the subsequent replies since I eat oily fish a couple of times a week and was initially a bit alarmed. However I don't take fish oil supplements so will just keep watch for the symptoms mentioned in the article. I do that anyway.

In short .... good to know about/be aware of but not a cause for great alarm for most people (IMHO)

Yes I’m large doses, fish oil, garlic, tumeric can all cause less platelet sticking, and increase the bleed time, anti inflammatory can do the same, but consumed in small amount through normal diet, it shouldn’t be a concern, if you experience extra bruising , consult your doctor, and wisely cut back on the foods, the lady the article talked about was on warfarin and she upped her supplements of fish oil to 2000mgs Instead of 1000mgs which changed her INR once advised to cut back her INR returned to within acceptable limits,

NICE removed Omacor (Omega-3 supplement) from being recommended for heart attack patients several years before NOACs even appeared, partially due to the same problem with warfarin and partially due to a lack of proof that it actually benefitted the patient.

Thank you for the replies. I started taking cod liver oil and malt as a toddler in the 1940’s and really didn’t think of it as a supplement, which of course it is.

A portion of salmon contains about 1g oil, so normal dietary intake would be only 2 or 3 grams per week but my intake is about 10g weekly, so that may have contributed to my frequent nosebleeds. I am hoping that stopping the capsules will improve that misery.

I learn something every day!

Thanks for this thread!

I’m very interested, partly because I’m pretty sure a lot of people on here do take both a DOAC and a high strength omega 3 supplement, and also because my EP absolutely categorically said I should be taking it. But now I’m wondering...!

In 2012 when I first saw the EP I had a diagnosis of SVT but no documented AF. The EP said the best thing I could do to ward off AF and for general heart health is take Omega 3 fish oil supplement daily.

When AF was discovered and Rivaroxaban started, I saw the warnings and stopped taking my fish oil supplement (tho continued eating lots of sardines and salmon). It wasn’t for another year that I saw the EP again and he was not pleased that I’d stopped the fish oil supplement. He said it’s still the best thing I can take to minimise AF deterioration and improve heart health, and that there’s no problem taking it with anticoagulation. He swapped me to Apixaban because it’s his preferred one, for people like me who have a history of gastric erosion/ulcer.

Strange, isn’t it? I was sure other people on the forum have been told it’s fine to take both... be very interesting to hear if so.

Hi I’m just wondering if anyone it taking turmeric for pain relief as I read it is a blood thinner and I’m on apixaban but turmeric use to help with my pain relief but now I’m on apixaban I’m not taking it and now of course my pain is really bad but a friend of mine said surely there are people of Indian countries who are on apixaban and do they stop using it in there cooking if they are on apixaban so I was wondering if there are any people out there that can let me know the answer to that thanks

Omega 3 has so many health benefits I take 1000mg daily along with my Eliquis and other supplements. You can research til the cows come home and you will find oodles of no's and yes's on the subject. Let's face it, I take a drug prescribed by a doctor that can cause me to have a bleed , a hemorrhagic stroke, or a PE (which I have suffered while take Xarelto) If I fall and injured myself I can bleed to death. If I'm in a motor accident and am injured , good luck if the ambulance gets there before I bleed out,so I make up my own mind on what I think is safe for me. So far so good. I cant tell you what to take but read read read. The research you should be looking for should be current...not from years ago. And you need to check how many people were involved in the trial and for how long.