Apparently the effect of dabigatran is enhanced with lovastatin or simvastatin. The risk of major haemorrhage is increased by over 40%. This effect does not appear with other statins.
The problem with dabigatran is that there isn't a standard way to test its concentration (unlike warfarin). It was found in its trials that there were fewer strokes when its concentration was measured in a laboratory, but of course that would negate its main benefit of apparently not requiring testing. This was kept quiet at the time and caused quite a scandal when the details were finally released.
Written by
MarkS
To view profiles and participate in discussions please or .
Just an additional bit of information from the Aussies downunder - have a go at this - its a safety alert from the Australian Department of Health, Therapeutic Goods Administration
Thanks, Carneuny, there do seem to be a lot of interactions. I'm sure more of these will come out in time as they didn't show up in the original trial, for whatever reason.
MarkS Thank you for this. I had an appointment with my GP this morning to have a steroid injection into my frozen shoulder. I wrote out details for him and he is going to alter my Simvastatin prescription.
Have you tried a osteopath for your frozen shoulder - I had this a few years ago before AF. Had pain killers, phsio, chyropractor nothing worked over a 9 month period. Went to the Osteopath and cured in 6 weeks. Down side you have to pay for it.
cassie46 Many thanks for this. The pain on certain movements is awful - like being electrocuted. I am told that it is bursitis. Googling it revealed that we each have 65 bursas which are like cushions between the joints.
I will certainly take your advice if this steroid injection doesn't work.
That's really useful. I can only take Pradaxa so I'll keep that in mind if the Practice Nurse suggests statins, as there is now no low threshold for cholesterol to be prescribed a statin.
Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.
Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.
Advice needed on statins please
Tesco and Dabigatran
Does anyone record their Afib, and their resulting use of dabigatran, on a MedicAlert bracelet?
Can medication be reduced after a certain time with no problems?
