Still no testosterone: Stopped Abi last... - Advanced Prostate...

Advanced Prostate Cancer

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Still no testosterone

Still_in_shock profile image
21 Replies

Stopped Abi last year and T went from 0 to 20.

Onco stopped Lupron 3 months ago, T still at 20. And my PSA is still <0.02

So my adrenals are producing T but not the boys!! I was on Lupron for 30 Months, I guess it'll take that long to come back is it does??

Do we think the Lupron is still dissipating?

On the good side, my anemia is no longer, and my Lymphocytes gave FULLY recovered from IMRT nearly 2 years ago.

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Still_in_shock profile image
Still_in_shock
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21 Replies
GP24 profile image
GP24

It will usually take about a year for T to recover. Often it does not recover completely at all.

London441 profile image
London441 in reply toGP24

Not usually, it depends on several key factors. Those factors could make it far more or less likely to return, and the range is wide. Mine returned fully in 3 months and it’s not uncommon.

To still in shock: I presume you were getting 3 month Lupron shots? Based on that, 3 months is early, especially after 30 months. Give it time. Do you know what your baseline T was at diagnosis? That is helpful in managing expectations. Your age, and especially your biological age/overall health matter a lot. The more strong and fit you are, and the less co morbidities you have, the more likely you’ll get it back.

HCG can help the kickstart, and it’s safer than TRT of any kind.

Mgtd profile image
Mgtd in reply toLondon441

I agree with London. However, one additional thought came to mind. How much do you exercise and more importantly do you do resistance training. Are you heavy? If you are, Weight loss will improve T.

There are exceptions to every rule. Mind came back in 2 months. I could really feel the difference as it rose. At 80 next month I am back to my benchmark of around 700 before ADT.

Still_in_shock profile image
Still_in_shock in reply toMgtd

I do excercise, Im 20 lbs overweight, cant seem to rid it.

All this ADT caused metabolic syndrome especially Insulin residtant Diabetes, and the 24 hour insulin causes weight gain.

Mgtd profile image
Mgtd in reply toStill_in_shock

Not to belabor the point but I was referring specifically to weight training to build T not just aerobic exercise like walking, biking, swimming etc.

If diet in combination with exercise is not working to reduce weight and raise T then you may have to consider T supplementation if approved by your doctor.

Regarding the time it takes for Lupron to leave your system after stopping it my experience for a 6 month dose was it took 2 to 3 months.

Still_in_shock profile image
Still_in_shock in reply toLondon441

I was getting 6 month shots.

Doesnt HCG cause Gynemastia??😂

London441 profile image
London441 in reply toStill_in_shock

HCG does not cause gynecomastia.

If you were getting a shot every 6 months, and the last one was 3 months ago, it's not time to expect any rise in T yet.

Meanwhile, get rid of the extra 20 lbs if you can, and really try to reverse the diabetes as much as possible. I know it's not easy, but these are definitely going to get in the way of your desired testosterone return. See if you can increase the exercise, especially weight training. I would also eliminate almost all carbohydrates from the diet if you haven't already. Certainly sugars, pasta, beer, bread etc. Plus eat less. To lose weight you need to eat less than your furnace is burning, it's that simple. Again, simple but not easy of course, especially since the Lupron slows metabolism. But you will feel transformed in a short time if you commit.

Mgtd profile image
Mgtd in reply toLondon441

We really do think alike on the value of exercise and diet in fighting this cancer and probably regarding overall health. However it has been my experience that for many people, it is easier to determine reasons why things are not possible or not put in the effort required to overcome obstacles. This probably true for many things in life.

I am not going to live forever but my goal is to make those “life” years really memorable and reduce the actual time I spend in active dieing by life style and getting medical treatment if applicable.

London441 profile image
London441 in reply toMgtd

You are quite correct! Agree completely, especially about the role of human nature. Coming up with reasons to legitimately opt out of effort is the advanced method of simply not trying. I put myself above no one, it was a hallmark of my youth.😀

Still_in_shock profile image
Still_in_shock in reply toLondon441

No, the last 6 month shot was 9 months ago.

I skipped the one 3 months ago.

So 3 months from Lupron wearing off

you’re suggesting everything I’m already doing weight gain is caused be insulin I am watching what I eat, I am working out Blood work says I’m healthier than I ever was!!

It’s all a side effect of ALL my T being stopped for the last 30 months

I know when T resumes it will reverse itself

Gynecomastia IS a side effect of Hcg in men

When I was bodybuilding there was a term for guys using extra T and Steroids Bitch Tits from estrogen increasing as a by product of T increasing too fast HCG will do that

London441 profile image
London441 in reply toStill_in_shock

Yes it can cause gynecomastia, but unlike supplemental T, it’s only to be used for a short time, to stimulate natural production. Supplemental T must be used continuously, for life if the body is allowed to adapt to zero natural production long term. A short course of HCG to jump start the pituitary is unlikely to be a problem, and some tamoxifen along with it will mitigate it.

As for the diet and exercise, what I’m suggesting may actually be quite different than what you’re doing. ‘Watching what I eat’ and ‘working out’ are very vague terms, so I can’t know what they mean for you. However, if you work out hard and restrict your food enough to be in a caloric deficit, eliminating all simple carbs (and most complex ones), you will lose the fat. Admittedly, that requires a lot of discipline. It’s not for everybody.

Or you can just wait for it to come back when the Lupron wears off. But after 30 months of ADT, with insulin resistance and 20 extra lbs of fat, the odds are not in your favor. That’s why taking action now matters. Great luck to you!

BluesmanNick profile image
BluesmanNick

17 months after my last Zolodex implant and there's still no change in my T. I was totally fed up!

So, I got a referral to an Endocrinologist and I'm now taking T gel daily (a half dose).

My Endo will review my bloods, etc, in 2 months, to see if the problem is my pituitary gland or my gonads.

I can feel the muscle and balance benefit after only one week!

petabyte profile image
petabyte in reply toBluesmanNick

Did the endocrinologist talk about clomid and hCG? These can help kickstart T production following ADT.

BluesmanNick profile image
BluesmanNick in reply topetabyte

No, not at this stage. I just wanted to get things happening straight away!

I'm sure we'll look into any other possible options after the review in 2 months.

If I have no alternative option at that point, I'll still be happy to apply the gel every day. 👍

As an Aged Pensioner in Australia, it only costs me AU$7.70 for a 70-day script. 😉

petabyte profile image
petabyte in reply toBluesmanNick

I read that if you replace testosterone this can halt any natural recovery and you may become dependent on replacement. I don't have references though, I'm not there yet but was planning ahead by doing some reading a while back.

BluesmanNick profile image
BluesmanNick in reply topetabyte

Here's one reference I came across...

medshun.com/article/does-tr...

London441 profile image
London441 in reply topetabyte

This is true! The law of drugs applies. If you tell your body you don't need a particular process for an extended time, it becomes harder, then impossible to take it back.

Maybe for older men, permanent TRT is a great option. After all, the definition of 'permanent' uh, changes.😀

j-o-h-n profile image
j-o-h-n

I know this request is dated, but could you please update your bio..... Thanks...

Good Luck, Good Health and Good Humor.

j-o -h-n

Still_in_shock profile image
Still_in_shock

So my original question remains!!

How long does Lupron stay in your system past the dosage time.

I DID NOT take my shot 3 months ago, when the 6 month dose theoretically was to wear off.

Forget the exercise and diet, I have that covered.

Is there still Lupron in my system?

GuitarMaker1978 profile image
GuitarMaker1978

I have been on ORGOVYX not LUPRON but every study I’ve read suggests that full testosterone recovery time with LUPRON is typically equally to the length of time you were on it. Best wishes for a fast and full recovery

Still_in_shock profile image
Still_in_shock

To add, I paid for some blood tests with Quest last week. Testosterone resulted at

20 ng/dL, that was last week.

I got tests this morning at UCLA, and they use Their own labs in Westwood. The result was

40 ng/dL.

Quest was 4 PM, UCLA was 8 AM , could it be the labs difference, or the morning effect that state T is higher in the AM?

Now, to add insult to injury. My old Endo not at UCLA did labs on me 2 months ago CBC and CMP among others through LABCORP.

I paid Quest for those to verify, and had the same done per my ONCO at UCLA this morning.

LABCORP, and UCLAs CBC and CMP were really close, even though they were months apart.

But Quest was all over the place compared to UCLA, days apart.

I no longer trust Quest!!!!

BTW my PSA was <0.1 at UCLA!!!

(Trust but verify, PSA was <0.02 at Quest. )

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