An interesting bit of news suggesting Aspirin may have anti-metastatic effects… though this research is specifically talking about lower grade cancers, and the article doesn’t mention Prostate Cancer.
The fact it’s being reported by BBC news feels like a heavier confirmation than the usual ebb and flow of research articles.
Thanks for posting that Broccoli24. I could do with a bit of luck . Last week my PSA results 0.35 were nearly double the previous 3 month result 0.19. I had a triple bypass Dec 2023 and have been on blood thinners ( amoungst other meds) since. I take 100mg of aspirin daily and will be on that for life.
" We'll see"...says the blind man!😀
Good luck to you! 🤞
ASPREE, has shown increased death rates of users, also one must be aware of the rebound effect of discontinuing the long term use. Then, theirs gastro bleeding and thinning risk, and the interaction issues of NSAIDs. By the way, BBC is notorious for information counterfactual. If we dont have direct evidence of benefit fighting PC, should we gamble?
Thanks, good for thought.
Yup. My doctor took me off daily aspirin five years ago due to study.
“BBC is notorious for information counterfactual” oh really got a study that shows that? against what benchmark, other news organisations?
perplexity.ai/search/exampl...
this answer deserves the utmost contempt. Change that prompt to any news outlet and get just as superficially impressive an output. It is peak irony that on a forum discussing scientific method, you accuse the bbc of having a “notorious” counterfactual bias then you play this cheap ai answer card. jfc.
Why, because arrogance says so? Evidence is evidence.
if you have a preference for asking AIs instead of using your brain, ask them all if the BBC “is notorious for counter factual narratives” and post the screen shot of the reply, if you have the balls to do so. Since you evidently use them to reinforce your own prejudice and dont listen to people thats all I can suggest.
Thanks very much… compelling reading!
Especially interesting is the possible overstated possibilities of gastro-intestinal bleeding caused by Aspirin.
There are lots of supplements and adjuvants that theoretically might prevent cancer. Also there are many proven to affect cancer in different ways from preventing angiogenesis (attaching to a blood supply) to apoptosis (cell death). Not one has even come close to a cure. (Actually AKBA in Boswelia extract seems to affect a cure in some cancers).
Looking at PSA doubling time though, many slow cancer, or may hinder cancer's development or ability to spread to distant sites.
This being said, one must look first at potential negatives and for many of us (older) aspirin's risk may outweigh it's +. Also one must look at oneself versus any chemical. Consider curcumin. I think Curcumin + Piperine for absorption is + all around, BUT, not for me, why? Because I take Orgo + Abi and Abiraterone. Should I continue to take Curcumin while taking Abiraterone and I were to continue to take 2 grams of curcumin every day, the effect on the Abiraterone would be to increase my blood level of Abiraterone by 4 to 8x, talk about potential for adverse effects, (Nuclear hot flushes?) that's the same as my taking 8 grams of Abiraterone per day. (Abiraterone use Cytochrome P450 3A4 enzymatic system). The take-away is to cross reference the "you" (your issues and your meds) with any supplements.
Here is a list of ones that I like that I CANNOT take because of Abiraterone = TransPterostilbene, Berberine, Ashwaganda, Astaxanthin, Green Tea Extract, Piperine, Astragalus and Cayenne extract. ALL of these interfere and damage canncer in some way (I focused on anti-angiogenic properties because I did not want to start ADT for 5 months).
Then, starting ADT (Abi + Org) ALL of the above were contraindicated, so I sorted ones that are anti-angiogenic, apoptotic, or in some way negatively affected cancer without known risk, and that left me with: ALCAR; ALA; NAC; TMG and L-theanine and Modified Citrus Pectin.
Do these help? Well, the first batch (before Org/Abi started in January, I started in August, and in August my PSA was 56, in January it was 49. Certainly not conclusive (n=1). Then in January I dropped the first batch and started the 2nd while on Abi/Org, at 5 weeks my PSA had dropped from 49 to 0.8. (A drop from 49 to 25 would have been a + indication). Did these help? Statistically = unknown.
Also one must consider all data, for instance, Boswellia extract, particularly one component AKBA, which stands for Acetyl-11-keto-β-boswellic acid, is very, very promising. But here is the catch: You can buy it on Amazon, about a penny per milligram and the max is 66mg/2 tablets. But, now the catch: The research, translated to "you," you would need about 700 milligrams per day. So sure, you could spend $7/day, but aha....the risk: who knows?
OP you use Broccoli as an ID and so you clearly know about sulphoraphane a substance known for it's apoptotic action. Great stuff, but cooked broccoli = 0. Broccoli sprouts has 20-50x of broccoli. But, grow sprouts wrong and you can become very ill or die from bacteria (though I believe it's well worth learning to sterilize your seeds before sprouting).
Like life, there is opportunity, but there is also complexity.
As I understand it, aspirin triggers the synthesis of resolvin which helps clear up cancer cell debris which can be a breeding ground for the formation of new cancer cells.
The articles below explain it more clearly:
Aspirin.
Sometimes for a good reason, aspirin is used to treat a woman's headache. So grind it to a pulp and cover your dingus with the powder and ask your wife if she prefers to take it orally or as a suppository. That will definitely make her smile.
Good Luck, Good Health and Good Humor.
j-o-h-n
Immonotherapy Overview 
Newly Diagnosed Metastatic Prostate Cancer
Complementary Therapies - Your Experience?
Healthy Eating May Keep 'Low Grade' Prostate Cancers in Check.
