i lowered my psa again down from 3.3 to 2.45

[iloweredmypsa]

Just pleased to report out that I have managed to lower my PSA for a third time in a row over the last 11 months, starting from when my prostate cancer was diagnosed last January. In January 2024 my PSA was 6.4, then in April to 4.7, July 3.3, and now November it's 2.45. I have only made diet changes and I now take some supplements. No surgery or radiation. Am I on to something real, or is this something others have done in the past? Thanks for any information.

[Tinkudi]

what supplements and diet changes. Why don’t you mention it

[iloweredmypsa in reply to Tinkudi]

it's fairly lengthy and they way I went about introducing them I feel is important. I started with Water Food and Air. I clean my water and air. And I went largely vegetarian. I drink pomegranate juice and take a pomegranate seed oil supplement. I augment that with elegiac acid and luteolin supplements. I also focus on ursolic acid, rosmarinic acid, and carnosic acid found in Rosemary. I make those more bioavailable with rapeseed oil and piperine found in black pepper, as well as hops and the xanthohumol it contains. I am unfamiliar with how to transmit the substantial amount of information I have on the subject. perhaps you can suggest one.

[Still_in_shock in reply to Tinkudi]

He stopped TRT!

[addicted2cycling]

Welcome

Congratulations with the PSA reduction and may it continue to lower. Often times a diet change along with exercise can help reduce PSA numbers if it is also partly due to inflammation, infection, BPH.

It could be helpful for others if you would give your diagnosis information and any other info you deem would be beneficial for understanding your protocol.

p.s. - as always, anything you do not wish others to know about should be withheld

Good Luck

[iloweredmypsa in reply to addicted2cycling]

I thought that information was in my Bio. Here it is for review. Prostate Cancer diagnosis Dec 2023. MRI guided biopsy revealed index tumor 1.4cm diameter. Gleason 3/4. Isolated. currently on AS. iloweredmypsa from 6.4 to 4.7 to 3.3 to 2.45 over a period of 11 months. Best of Luck to everyone in doing the same.

[addicted2cycling in reply to iloweredmypsa]

Thanks

[ulfhbg]

Hi!

Like Tinkudi wrote, perhaps it would be a good thing to list the supplements you’ve decided to use and perhaps also write what type of changes you’ve done to your diet. How are you with excercise and have you done any changes there?

I would say that it’s rather difficult to have any view if your doing ’the right things’ that might impact your PSA trend just by mentioning that you’ve done changes but not what you’ve done.

Anyway, nice to see your downward PSA trend 👍

[iloweredmypsa in reply to ulfhbg]

all the details are at iloweredmypsa.com. if you comment there I can easily be more specific and responsive. Thanks in advance for taking a look

[Drago101]

Wow amazing job. Ive read that inflammation is the cause of all disease/illnesses. So if ur diet is lowering inflammation, doesnt surprise me. What is ur diet?

[iloweredmypsa in reply to Drago101]

Thank you so much !! Yes, no more edema in my legs, 2 inches more room in my shirt collar, so I guess I am experiencing less inflammation. I've been keeping good notes on what I have been doing, and I wrote it all down. I sent you a dm with the details.

[Drago101]

thnks! will review

[Vynbal]

While your numbers are encouraging, it is important to remember that PSA is not cancer. Be sure to stay vigilant with more than just PSA tests to keep an eye on your cancer.

[iloweredmypsa in reply to Vynbal]

thank you. Currently MRIs are also on the schedule of events. Other tests may be done based on what happens next.

[Tall_Allen]

You don't have advanced PCa, which is what this forum is for. PSA is not prostate cancer.

[iloweredmypsa in reply to Tall_Allen]

Thank you for your thoughtful comment. A moderator, Darryl, messaged me informing me I was welcome to share my story. Maybe he is also misunderstanding something? idk

[Tall_Allen in reply to iloweredmypsa]

Darryl has a different forum for men with your diagnosis:

healthunlocked.com/prostate...

Your situation is useless on this forum.

[iloweredmypsa in reply to Tall_Allen]

thank you for that link to a different diagnosis. Your analysis that renders as useless a systematic solution that treats every area of the body simultaneously seems strict. For example, I am getting good advice from several sources here, and I am finding what some posters have to say about my situation useful. Thank you again for the other link. I appreciate it.

[Stevecavill in reply to iloweredmypsa]

He’s just saying your post is irrelevant to this forum, as this forum is for advanced prostate cancer, which is not your diagnosis

[London441]

Congratulations on your efforts. As has been said, the problem with your post is that you are coming from a completely different disease stage, yet it can easily encourage men with advanced disease to follow your protocol, or similar-in lieu of conventional treatments. Treatments without which they may end up wishing they had started much sooner. Treatments without which they may die trying to avoid them. It happens, and it’s not that uncommon.

Supplements and change of lifestyle are positive to be sure, but in a forum like this, testaments to lowering PSA with them is often tantamount to offering false hope.

[iloweredmypsa in reply to London441]

I am not suggesting that anyone else follow what I am doing. I am just telling my story. I am not suggesting a course of action for anyone else. I am asking and have been asking for the opinion of others about what I am doing. I have been learning that some have tried the same and learned different things about their journey that they are sharing with me.

[London441 in reply to iloweredmypsa]

I know, and again good for you. However, despite it not being your intention, the influence is real. If you had advanced disease it would be appropriate. This is the distinction.

[iloweredmypsa in reply to London441]

Thank you for your opinion. I have previously messaged the mods and they opined that I could tell my story here and receive feedback on it. The mods are telling me what I am doing is appropriate. I know this is in conflict with your opinion that I do not belong here, despite the welcoming attitude of others and the helpful information I am receiving from those who have seen and lived though a lot more than I have.

[lcfcpolo]

That is great news. This might help many people but it needs a health warning attached. In a Advanced Prostate Cancer forum, where many people have a terminal diagnosis, please always clarify that your on Active Surveillance only, as your disease has not spread. People unfortunately cannot come off of medication at stage 4. What your post reminds all of us is that lifestyle changes can help a lot though, alongside the treatment in our case. Good luck and hopefully you keep everything at bay.

[iloweredmypsa in reply to lcfcpolo]

It's surely a roller coaster ride. One minute it all seems good, the next minute, not so much. I believe my bio states I am active surveillance. best of luck to everyone out there.

[KocoPr]

it is good that you are taking a diagnosis into your hands and that will definitely help you in any health issues you may get. You also must include your oncologist in your monitoring as they know this disease better than oneself.

They have seen it all, but they are also too busy to keep up with your non advanced disease, and also they are not trained in nutrition nor herbalism.

Keep doing what you’re doing with your own testing. You might want to try ultalabs for a better price for the Quest tedts.

STAY VIGILANT!

[iloweredmypsa in reply to KocoPr]

I did see an oncologist, and he returned me back to my urologist, advising me that "you do not want to see me". I follow my urologist and PCP advice. And "nutrition and herbalism" has evolved into cellular microbiology and bio-chemistry. From what I am reading of the current University research, it's no longer if such biochemistry is effective, but more about what are the bio-mechanisms and metabolic pathways that are taken to achieve such effects.

cell.com/iscience/fulltext/...

Looking at the graphs of prostate cancer death progressions through ferroptosis against a series of PCa types, (androgen-positive sensitive LNCaP and VCaP, androgen-positive unsensitive 22RV1 and C4-2B, and androgen-independent PC3 and DU145 cells), it's just shocking to me how effective punicic acid is when compared to other treatments.

wrt testing labs, my current thinking has me wanting consistent results though going to the same lab at the same time of morning. That removes the variations between different labs. So far, my multiple layers of insurance has been creating a satisfactory dampening of the costs. Thank you for your post and your upbeat advice to stand strong and fight. It is appreciated.

[Pinkyboy]

I have an acquaintance, much younger than me, who has recently been diagnosed with PCa with lymph nodes involved. He is rejecting SoC, instead going with “supplements” as suggested by someone on the internet. Unless he changes, I don’t foresee a happy ending for him. So, I get concerned when internet “information,” or one-off personal stories, suggests perceived success without full context. The topic of this thread is virtually worthless to those of us with “advanced” PCa, yet one never knows who might not realize it and make unwise decisions.

Rob

[iloweredmypsa in reply to Pinkyboy]

Thank you for your point of view. I wish you and your acquaintance have the best possible outcome. I am not recommending that anyone do anything. I am sharing my story and learning from others. I am not rejecting SoC, I am following my doctor's orders, Ron. I appreciate your cautionary story, and I will form my own amalgam solution for myself, built out of comments like yours and others, as well as from what my doctors advise me. Here is an interesting piece on what I like to think is Doing the Right Thing when it comes to Medical Situations. I present that to you for your consideration. iloweredmypsa.com/?p=115

[Tommyj2 in reply to iloweredmypsa]

Frankly…if you don’t want others to mimic your path I don’t really understand why you felt the need to announce your success in an advanced cancer forum…..

You are ages away from the situation most on this forum find themselves in…..

[MrG68]

Good for you.

For me its always nice to see someone get positive results. It's a welcome change from the opposite.

Hope it continues for you.

[Steve507]

This is not the right forum.

[iloweredmypsa in reply to Steve507]

I have cleared it with the mods. But thank you for challenging my right to be here and learn from those with more advanced conditions.

[Lrv44221 in reply to iloweredmypsa]

You have a right to be here

Try to ignore the negativity with some people 💜

[Steve507 in reply to iloweredmypsa]

Passive/aggressive Ken! 😉

[Lrv44221]

congratulations lower!!! Yes you are on a good path. Since cancer CHOKES on oxygen I would like to see you add oxygen. This can be done with exercise like walking dancing swimming. (Moving the body)etc

two supplements that I give my husband along with many others are; berberine which helps with the fat ( prostate cancer is driven by fat)and panacure which is wormer for dogs. This helps with abnormal cell signalling .

I m happy for you. Thank you for sharing. I believe everyone has to do what works for them both in their mind as well as their body

💜💜💜

[7OaksTom]

Thanks for sharing. I have Gleason 9 advanced hormone resistant metastatic PC, diagnosed in October of 2023 and being treated with the SOC radiation and testosterone killing drugs. This morning I was thinking of telling my MO next week that I want to stop and let nature take its course because of the side effects. When I read your story I thought, hey, it looks like I can do that using your approach. This was the danger of your posting your story in this forum. I very seldom I ever read the profiles of posters, but I assumed you had advanced PC as well.

This is the point of the earlier posters who have been in this battle for far longer than I have and learned that there are no quick fixes.

[Thunderball1]

Metformin, atorvastatin, and mebendazole, are worth your researching into also as they are well-known repurposed drugs for PCa. I read your blog website account of your history. You are doing the right things and getting great results. The metabolic approach to starving cancer using natural supplements and old repurposed inexpensive drugs is becoming increasingly known. That's good for all patients and especially their families to know about in case PCa strikes others at an early stage. PCa has a strong familial aspect. I am also on active surveillance and taking all those supps too to try and stay that way. My PSA also dropped roughly two points (6 to 4). Just had a second biopsy. But my brother had it worse so hopefully I can avoid the treatments the other advanced PCa experts on here have spoken about. Treatment for cancer is evolving and good information is priceless.

[iloweredmypsa in reply to Thunderball1]

thanks for the vote of confidence

[j-o-h-n]

Be what you is, and not what you ain't, cause if you ain't what you is, you is what you ain't.

Good Luck, Good Health and Good Humor.

j-o-h-n

[dhccpa]

Watching the back and forth about whether the poster belongs on the Forum here, I thought many good points and caveats were made.

Isn't that part of why the poster posted? And he says he wrote the mods. Unless Darryl contradicts that, many of you wasted time and effort on pettiness. Others weighed in with wisdom, and appreciate all viewpoints within that spirit.

[CAMPSOUPS in reply to dhccpa]

I'm thinking not such a big deal. His diagnosis and his approach to treatment all converge for him to be in the active surveillance group. Not here in the stage 4 advanced group. He seemed to be confusing being told this isn't the group for him to thinking everyone was telling him to leave the forum period. I noticed he re-posted under the "prostate cancer network" which is where he fits better.

I do think though that Darryl was hoodwinked.

[dhccpa in reply to CAMPSOUPS]

Anything is possible on a PCa forum!

[AliHaidar]

I had a similar situation to what you are describing. I also added fasting to the mix and credit it with assisting in lowering my PSA. However, a few years later I had another small spike in PSA and did further testing. I was diagnosed with prostrate cancer confined to the prostrate and after radiation treatment, my radiation doctor pronounced me "cured". I was not on a forum with so much good guidance at that time and again went into relaxation mode.

I was therefore totally surprised when my PSA went up again and testing revealed that the cancer had spread to my lymph glands and later, my bones. To this day, I think that I should have been more agressive in testing in my earlier days and never given the cancer an opportunity to spread. When I had the radiation treatment, the standard CT scans and bone tests showed my body to be toatlly clear of the cancer. I recommend diligent testing. Your situation could be far different from mine and the PSA results could be from benign sources like inflammation. However, I suggest diligent and comprehensive testing and consultations with your oncologist to make sure you know at the earliest possible time what your true status is.

[Thunderball1 in reply to AliHaidar]

Can you say what you mean by comprehensive testing? Standard CT was clear and not enough so what then? What tests are best? I had a positive PSMA PET but urologist explained it should not be used for prognosis planning. I have confined localised PCa.

[AliHaidar in reply to Thunderball1]

I would suggest that you add a good oncologist to your team if you do not have one already and ask him this question. My reply is anecdotal. That said, I would have suggested the PMSA PET. My theory is that I treated the cancer that showed up in my tests and, to this day, my prostrate tests negative for PCa. However, sometime in the timeline before my radiation treatment, the PCa escaped the prostrate in micro quantities that did not show up on the CT. Once these colonies showed up on my tests, my prognosis was much more serious. This disease is very agressive and now my treatment options are limited.

[Don_1213]

Are you getting a testosterone test done at the same time? A very well respected medical oncologist (who is my MO) - said "What good is PSA without T?" about the testing. Some of what you're doing may be reducing your T which can have the effect of lowering your PSA. You need both to tell the whole story.

[iloweredmypsa in reply to Don_1213]

Thank you for your thoughtful comment. I do get testosterone tests done at the same time. I discuss my testosterone situation and testing here. iloweredmypsa.com/?p=1 .

[Don_1213 in reply to iloweredmypsa]

A very interesting page. Of interest to me was what happened when you stopped taking T supplements - unlike the "common wisdom" that T never recovers after stopping supplements and you're on them for life once started.

What happened to you is exactly what my oncologist said would when I asked him about that common wisdom. He said the wisdom is wrong. He said typically most men after coming off T supplements recover to a level they would have been at normally (accounting for age..) So the body knows it needs T and makes it. There are always exceptions to the norm - and that's where the "common wisdom" probably started.

Thanks for the reference to your page - it's interesting reading.

[iloweredmypsa in reply to Don_1213]

I am pleased you found my site interesting. I'm hoping to step it up with an MRI that shows a reduction in tumor diameter. I remain cautiously optimistic.