Back in June, my PSA was 54
(gleason 8, extracapsular, clean PSMA-pet, no lymph nodes, a "few millimeters into the "pelvic sing").
I have not started any meds yet, nor any other treatment. I will within a few weeks (Orgovyx + Abi)
I asked my doc for a f/u PSA, trying to get a feel for what the cancer is doing, and expecting some number greater than 54...
Yesterday, my PSA was 48...
Does that commonly happen?
Negative PSA velocity?
I always thought that untreated PSA only went up...
Before treatment, there are several sources of PSA (PCa, BPH, prostatitis).
One time, while on Lupron vacation, in 2020, I had my PSA go down from 27 to 24, after intense lycopene intake. It resumed afterward, climbing to 36 before I resumrf Lupron. So your drop might be temporary...just keep testing.
How fast should your PSA drop after the first ADT treatment.
How fast does ELIGARD drop PSA? My urinary symptoms are worsening despite the injection, TURP and Testosterone under 20.
How long does it take for doxetaxel to bring down psa?
Non secreting PSA - How often will PC be monitored 
Does a big drop in PSA a month after the start of hormone treatment possibly represent a higher chance of cure? 
