Sorry to keep bugging y’all, but I keep having weird symptoms that I think may be related to the Abiraterone. I did a search here (wish you could search for “Abiraterone AND cough”) and see folks mentioning a possible connection.
About 3 weeks ago I had an awful head cold that eventually settled into my upper respiratory system. Got over that a week ago, but now I’m starting to have a tickle and tightness in my chest that makes me want to cough (generally a dry one?). Then I get into a cycle of coughing, and have to lie very still to get it to stop.
My question(s):
Does anyone else experience this?
What have they done about it?
I meet with my MO in 2 weeks and have a buncha questions involving side effects (cardiac, breathing, this cough, frequent urination, etc.) to ask him about. Until then I thought I’d ask you folks. Thanks.
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Jpburns
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Any allergies like hay fever? I get that tickle in the back of my throat with hay fever and it makes you cough. Once I get started, it keeps going. Just a thought because pollen counts are peaking in September for ragweed.
I forgot to mention, you may want to try Honeyworks kids organic cough syrup with ivy leaf extract. You can get it online through cvs.com. Some stop and shops sell it too. They have 3 or 4 different types. It’s the one with the green label on the box that includes the ivy leaf extract. . My father has a cough from COPD and GERD and nothing helped him. He would get horrible coughing fits. We tried the Honeyworks cough syrup with the ivy leaf extract and his cough is so much better now. It was amazing how well it works. I believe the ivy leaf extract relieves inflammation in the lungs and honey is very soothing as well. There have been some small studies on the herb.
Prednisone of course is a replacement for the steroid depletion from Abi.
So if all is well the amount of prednisone is a replacement.
But will prednisone still give the lowered immune effects when taken with Abi?
If so IMHO the cold was/is prolonged by the prednisone and now throat, lungs, are irritated not healing due to continued coughing. All conjecture on my half of course. MO's and or Physicians diagnosis will be most needed.
Steroid drugs, such as prednisone, work by lowering the activity of the immune system. The immune system is your body's defense system. Steroids work by slowing your body's response to disease or injury. Prednisone can help lower certain immune-related symptoms, including inflammation and swelling.
I had used Aberaterone continuously for four years. I also experienced persistent cough, but not severe throughout this period. I didn't bother much about this cough. When I discontinued Aberaterone after four years the cough also stopped.
I usually get very mild but lingering upper respiratory coughs in winter. I have been on abiraterone/prednisone since last March with no trace of coughing, and now wonder what will happen if I get a cough this winter.
Hard to say. I am on ADT, as well. In general, yes, I have more coughing than usual but connection is not causation. I feel it may be related to the meds, but is it. I caught covid in august during overseas travel. none of my family did and we were in planes, cars and general tight quarters. covid effects have been slow to go away (which is not unusual, either).
I would definitely look for something to halt the persistent coughing fits as that's probably irritating your throat and lungs and making things worse. Coughing once or twice, no worries. Coughing fits certainly sounds very uncomortable.
I answered this question before but I don't recall if it was to you. When first prescribed (about a year ago) abiraterone/prednisone I only lasted a couple of weeks before I developed a cough so annoying and persistent that I could not sleep. It became painful as well and I determined that I was going to stop the medication. (I looked at the side effects on line and it showed, if I remember correctly that 17% of users reported having coughing as a side effect.) I told this to my MO and she said that she had never heard of that side effect but it seemed like stopping the use was the best answer. Then I read something Tall Allen wrote that scared me into trying a half dose (500mgs). The cough went away and my bloodwork seems to be as good as it can be (PSA is undetectable.) In other countries they prescribe the half dose to be taken with food. I do not do that but that could be an option too. I have no idea if either method will work for you, but it seems to work for me. Good luck.
dunno if this applies to you , but if you are taking opioids, they are have antihistamine effects that can clear up a cough but when they start to wear off , coughing ( even hefty ) can ensue. I take chlorophentramine along with my opiates which helps the cough. Often times when this is happening, ( the opiates wearing off ) ….if something ( food, drink et. ) touches my uvula .. harsh coughing can happen which the chloropheentramine controls nicely. Just fyi
Well, I’m about to add Abi + pred to my adt regimen—just waiting approval from my dentist. I’ll post whatever SEs I develop as a result. Re a cough, I started BP meds a month ago and the Dr warned me about a possible cough SE. Sure enough, I developed a slight but persistent, infrequent cough. I need a cough drop at night sometimes to get to sleep. Hoping not to make it worse with Abi.
Correction: The reference re my dentist and starting Abi is a mistake. The MO diagnosed me with osteoporosis after my recent Dexa scan and has prescribed a drug for that. That’s the one I need dental approval for—confusion on my part as the result of a shotgun blast consultation with the MO. BTW, my MO said my osteoporosis is not a result of ADT because I’ve only been on it 7mos. It has likely been there for a few years.
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