Is there anything other than Docetaxal after Xtandi failed

[Knittingque]

Xtandi failed, I am non met castrate resistant. Mo suggesting docetaxal next, l am wondering if there is any other way to go please.

[RyderLake2]

Hello,

I too faced the same choice. What comes after the ARPI drugs like Xtandi (enzalutamide) when they start to fail? I was fortunate enough to get into a clinical trial investigating the use of radiopharmaceutical drugs like Lutetium-177 BEFORE chemotherapy. It has certainly worked for me. Other than a little fatigue no side effects. It is definitely worth looking into. Many countries outside North America are successfully using radiologand therapy and have been for many years. Hope that helps!

[Mascouche in reply to RyderLake2]

When Xtandi starts to fail, some people try the BAT approach to get it to work once more.

[Knittingque in reply to Mascouche]

Can you enlighten me on the BAT approach please

[kainasar in reply to Knittingque]

Search the posts. Lots of info.

[Knittingque in reply to RyderLake2]

l am located in Vancouver Canada do you know of any LU-177 trials there and what did thst involve in terms of time involved, outcome etc.,

[RyderLake2]

Hello,

Small world, I live in the Fraser Valley. The Lutetium trial I am just completing is called SPLASH. It is being run by the clinical trial team at the B.C. Cancer Agency on Tenth Avenue. The trial involved fairly frequent visits to Vancouver roughly every two weeks for bloodwork, scans, and meetings with medical staff. If you live in Vancouver it will be a lot easier for you than it was for me. I live about 110 kms east of the BCCA. You can search for clinical trials on “clinical trials.gov”. Talk to your oncologist. You want his or her approval. Good luck! 🤞

[Knittingque in reply to RyderLake2]

Thank you that is fantastic the Splash trial worked for you. We will be looking into that. Keep healthy!

[CAMPSOUPS in reply to Knittingque]

clinicaltrials.gov/search?l...

[Warriorthree]

Sorry I can’t help I’ve been on Xtandi for 4 years in November and works for me, Psa was 2600 before I started it’s now 0.02 and has remained there all this time , might be better speaking to Tall Alan , so sorry I can’t help.

[j-o-h-n in reply to Warriorthree]

Hint: Change your UserID to Warrior0.02.

Good Luck, Good Health and Good Humor.

j-o-h-n

[Warriorthree in reply to j-o-h-n]

Yes good idea certainly helped me thank you and all the very best xxx