New May 2024 from UCSF. I know not gold standard and only shows association, but for me that is good enough. Still do my burger or pulled pork sandwich 1-2x week, but only with avocado for inflammation reduction from eating those.
It does not happen over night, but small changes gives you a sense of helping your situation. Americans treat there bodies horribly, just go on a cruise. I'm satisfied trying and it's not that hard. 16 months of ADT and I have not gained a pound, but if my PSA goes up and my cancer spreads, then I know that I'm waisting my time trying.
Since for many, they will likely die of heart disease, etc before they succumbed to PC, there is a totally separate reason to follow a more plant-based diet. Better QOL while you live either way.
I really wish all the interesting nomograms to calculate recurrence probabilities did some analysis into patient health as well. Let's say 10 year recurrence probability is 50% from all the cases on file. These are nearly all people over the age 50 to 70+. Are the probabilities the same for the ones eating processed food, sitting on their couch, not doing exercise, not mediating, feeling stressed? I find that hard to believe. There are tons of meta-analysis studies and they simply go by the records they have for each patient which includes age, sex, BMI, maybe notes on diabetes type ii, but rarely much on diet exercise and general health.
Now maybe cancer once developed doesn't care! Maybe the odds are the odds, mets will form or won't form, and grow or won't grow, based on other factors. But it seems like there is a paucity of studies connecting recurrence probabilities or severity of disease progression to some estimate of the overall health of the patients, as a layperson understands that term: do they eat junk, eat a lot of processed meat, do they have a lot of visceral fat and do nothing about any of this? vs a cohort that might be intensely working on their overall health. It MIGHT be the single biggest influence on overall mortality over 15 years but I suppose because you can't easily randomise people into a study where one set are told to deliberately do nothing for their health and the other set are given intensive (and expensive) help with their diet and health, there is "no good data" on the whole subject.
Yes, no money, too many variables, etc. to ever be a SOC. So, in absence of a SOC, we use logic, like you speak about (please note that logic is a "dirty word" in the scientific community so be careful).
You are right in sone way, but it’s not that logic or common sense are dirty words. It’s just, in my opinion, that there are many things that do not follow our logic. There are proteins that seem to protect you from cancer but once you have it they tend to promote it, and stuff like that. It’s a complex disease and science works with the best proof available at the moment, not with the best logic (even if, thanks god, they often go together 😂 ) we would need a way to prove that the logic is backed by the results.
Point was when no SOC, meaning no way to study this practically and get a gold standard "science Based" study decision, you go with what you have. Your own intellect acting as best you can based on the facts you have at the time.
You nailed it I think. To be sure you should not rely on self assessment but be sure of what people eat, if and how they exercise and so on. And ethically asking someone to be a couch potato and eat junk food would not work. So observational is all we have. There will be some short term results of some metabolic diet and so on, but one thing I can say: all diets agree on two factors, no processed food (and not talking about meat only) and no sugar (trying to avoid also the hidden one used as preservative for example). With exercise it’s easier: it makes you release myokines so it’s good anyway 😜
My primary diet is centered around plant based , that said , I have salmon, ground chicken patty one time per week. Meat burger grass feed maybe one or two per month. No dairy. One avocado daily , Ezekiel cereal . Egg whites only. Tofu , veggies. Periodic fasting. All this has been a game changer for my overall health. As for my PCa it's hard to say to what degree . I do think it helps to minimize any ADT SE's I may be subject to. So far no weight gain or fatigue . No matter what, healthy food choices has it's benefits. Research on rumble - The Surprising Potential of Ivermectin Against Cancer: Dr. Kathleen Ruddy ( 49min interview). Let me know what ya all think. Must say I was inspired enough and am now taking it. Not advising just what I am doing.
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