CC-94676 or BMS-986365 is a highly selective AR degrade for castration resistant prostate cancer, the first good results were reported in January this year, but in September we will get more news at ESMO 2024
cslide.ctimeetingtech.com/e...
search page but I would try also "solid tumors" as search term
Funny thing on my last appointment with my MO at Medical College of WI he told me he is going to this conference and I will be there same time on holiday. So we are meeting up for dinner! That is why hotel rooms are over $500/night
Pssss Park benches are free...
Good Luck, Good Health and Good Humor.
j-o-h-n
I gave those up last year😀
In your wide reading, how is metastatic castrate resistance defined? More specifically, does merely rising PSA qualify, or do scans have to show either growth in existing Mets, or the appearance of new Mets?
I ask because some doctors apparently draw conclusions based solely on rising PSA without radiographic progression.
Thanks.
I must say it's a debated topic, especially with evolving measurement techniques and tools. Technically CR means that despite the very low testosterone in your blood, you have an increased activity if the cancer, that can be measured by PSA or PSADT but also via radiographic progression without PSA changes.
Yes, I understand that progression on scans without rising PSA is serious. But the opposite--rising PSA but no visible progression-especially if after rises PSA is still 5 or less- is more puzzling.
Could be a factor, say, in whether chemo will work effectively at a particular moment.
I guess this topic applies more to men who still have their prostate never having had RO or radiation.
): "I take no radiographic progression over PSA level any day"
Just checking in to make sure I don’t need to be doing anything else at this time? 
Diet and Exercise Presentation at UCSF
Proxalutamide vs covid, your thoughts please?
Radio sensitizers and Microbiome 
