Names of ADT and antiADT Drugs

[Worked_the_World]

I would like a simple list of the medical names and brand names of the various prostate hormone treatment drugs to keep them straight.

[vintage42]

Brand Names and Generic Names (any corrections welcome)

--

Androgen Deprivation Therapy (ADT)

LHRH agonist and antagonist medications stop body from producing testosterone.

Lupron (Leuprolide)

Eligard (Leuprolide)

Firmagon (Degarelix)

Orgovyx (Relugolix)

--

Androgen Receptor Inhibitors (ARI)

Anti-androgens block testosterone from reaching cancer cells

Androgen Receptor Pathway Inhibitors (ARPI)

Xytiga (Abiraterone)

Androgen Receptor Signaling Inhibitors (ARSI)

Casodex (Bicalutamide)

Xtandi (Enzalutamide)

Nubeqa (Darolutamide)

Erleada (Apalutamide)

--

Chemotherapy

Only kills growing cancer cells

Taxotere (Docetaxel)

[Worked_the_World in reply to vintage42]

Thanks a bunch. I have copied and saved.

[pe43 in reply to Worked_the_World]

There are also the LHRH agonists Zoladex (Goserelin) and Trelstar (Triptorelin)

[Still_in_shock in reply to vintage42]

I believe Zytiga/Abiraterone is an androgen synthesis inhibitor.

[vintage42 in reply to Still_in_shock]

"I believe Zytiga/Abiraterone is an androgen synthesis inhibitor."

So synthesis would mean production, which the testes do, and which ADT inhibits.

The Zytiga site says it "inhibits androgen at 3 sources—the testes, the adrenal glands, and the tumor itself." So it apparently inhibits both production and reception. I thought that might make it an ARPI rather then an ADT.

[Bethpage]

Under chemo, there is also cabazitaxel/Jevtana.

[vintage42 in reply to Bethpage]

Yes, thanks.

[ron_bucher]

Here is a great link to bookmark: cancer.net/cancer-types/pro...

[vintage42 in reply to ron_bucher]

It's the most comprehensive single site of information that I have yet seen.

[j-o-h-n]

And of course for OO LA LA :

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Good Luck, Good Health and Good Humor.

j-o-h-n Friday 01/19/2024 8:38 PM EST