the link to the study is in the article, but the key point is that if also in humans we have only two pathways to neuro endocrine…those two pathways can become targets to prevent it (if not to stop it)
UCLA researchers detail how prostate ... - Advanced Prostate...
UCLA researchers detail how prostate cancers grow into neuro endocrine (in vivo-in vitro)

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Maxone73
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Of Mice and Men
As a follow-on, here's a nice presentation and discussion video that looks at the state-of-the-art of actually trying to monitor phenotype evolution in the clinic using ctDNA (ie in humans). Upshot, not quite ready for prime-time but getting there.
This could help many many men in about 10 years, sadly I don't have that much time to wait.
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