Hi all - was diagnosed in early August with advanced prostate cancer with couple mets on pubic bone and l5. Treatment plan is:
Lupron injections every 3 mths
Daralutamide now daily
Chemo every 3rd week (docetaxel)
...this reads properly to you all and is the standard of care?
They also want to radiation when chemo is complete.
Yes, that is standard of care.
My husband was diagnosed advanced metastatic prostate ca. he has received SBRT on 3 bone mets and will be doing another round of SBRT on prostate and lumbar. He is getting Lupron, Zytiga and prednisone and is not mcrp. He wasn’t offered chemotherapy. Why do you think his doctor didn’t suggest it if it’s standard of care. Thanks
Did you ask him?
No, because in the beginning you don’t know what you don’t know so I didn’t know what the treatment options were and what to ask. I didn’t know until this post that chemotherapy is SOC. I’d heard triplet therapy was SOC, so radiation with ADT and hormones was triplet to me. So…..still don’t understand why one is chosen over the other. But, I’ll ask cuz now I know to ask!
Here's why it became SOC:
prostatecancer.news/2021/05...
Thanks for the link. Last paragraph seems to sum it up, but I will be sure to ask his doctor why he got radiation instead of the chemotherapy.
Both. In the PEACE1 triplet trial (docegtaxel+abiraterone+ADT) half got prostate radiation too. While it didn't yet prove to be significantly beneficial, the trial is not mature yet for the group that it is most likely to benefit - those with only a few metastases. In other trials, such men were found to benefit from "debulking" the prostate with radiation:
prostatecancer.news/2018/09...
PEACE1 and ARASENS have not yet run long enough to see the benefit in the subgroup who are oligometastatic. Until then, the best guess is that triplet works equally well.
exactly the same therapy I am on
Same theraphy I did (but with zytiga instead of Darolutamide).
Stay upbeat and positive. I was diagnosed with aggressive stage 4 prostate Cancer 10 years ago and still winning the battle, as they continue to throw the kitchen sink at me.
That is the relatively new standard of care. Your oncologist is definitely on his or her game. I even heard this described as the new Gold standard of care. Good luck.
Adding to the affirmative responses, that is now the (Gold) standard of care. Only difference to my treatment is Firmagon every 28 days instead of the Lupron . Wishing you great results!
Yes. That’s exactly the treatment I did. I’m still on Eligard (3 month) and darolutamide 2x / day but did Chemo (6 cycles) summer / Fall 2022 then radiation in Dec 2022 - January 2023. Radiation was to prostate, pelvic lymph node region and my one bone met on my right hip.
Thanks everyone for the replies. So far been pretty good on the Docetaxel 3rd day was pretty dragged down. On day 6 now and i feel pretty normal.
I will say i notice my heart seems to pound hard sometimes. Thinking perhaps that is the prednisone
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Triplet therapy question
