PSMA PET CT - MO said that there is n... - Advanced Prostate...

Advanced Prostate Cancer

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PSMA PET CT - MO said that there is no point to do this scan

Jdhanoa profile image
5 Replies

Hi all,

My dad was recently diagnosed with stage 5 metastatic prostate cancer with gleason 4+5. We are in a state of shock and trying to figure out the best treatment plan for him. I read online that many people recommended to have the PSMA pet scan done to target correct areas of cancer. However his medical oncologist said it wouldn't help in this case but i'm not sure why that would be the case, can anyone give information regarding this?

Thank you

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Jdhanoa
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5 Replies
Tall_Allen profile image
Tall_Allen

When one is polymetastatic, there is no point in using radiation, other than palliatively if there is pain. There is no such thing as "targeting metastases" in such cases. There are thousands of metastases, most of which cannot be seen by any type of scan. Think of it as mushrooms under an oak tree instead of weeds in a lawn.

Survivor86 profile image
Survivor86 in reply toTall_Allen

As a relatively new participant in this group (but not to advanced prostate cancer) I’m very appreciative of the informed comments you bring to the discussion. Could you shed any light on whether follow-up PET scans can be useful to identify new metastases when PSA rises after one is diagnosed with oligometastatic disease (with two bone metastases) and treated with SBRT. Is it inevitable that oligometastic disease will become polymetastatic ? Your comment that “there are thousands of metastases, most of which cannot be seen by any scan” prompts this question.

Tall_Allen profile image
Tall_Allen in reply toSurvivor86

It is unknown at this time whether playing "whack-a-mole" with metastases has any benefit. IMO, if it is safe, why not? But don't stop systemic therapy just because PSA goes down.

Survivor86 profile image
Survivor86 in reply toTall_Allen

Many thanks!

Justfor_ profile image
Justfor_

Easily explainable: When the MO doesn't have the answers, please don't pose the questions, he/she feels uncomfortable. Find one that does.

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