I did a search for this article & could not find. Sorry, if it has already been posted? It maybe different in that it gives a lot of detail on Pluvicto, ie., the manufacturer, mfgr. process, sites, half life, etc.
Would be interesting to know what experiences you Warriors have had with it. I am going for screening for Lutetium I&T Stage 3 Trial, next week.
from your bio “After 1.5 yrs. (2021) PSA rose to 0.4. Axumin Scan showed lesion, only on T-ll. Oligometastatic
Had it CyberKniffed.
3 mons. later PSA shot to 7.3, mets through out skeleton, large ones on T-4, T-8. “
I know everyone is talking about MDT with radiation. I don’t know how they feel about this, I am not buying it personally. Could it be the radiation that killed some and the rest got scattered everywhere else? From .4 to 7.3 and everywhere? I feel bad about this.
I think my RO, who has been doing this for many years (about as old as I am) thought it was more related to my increase in T, from the 200's to the 300's. But who really knows? With even more advanced imaging, possibly coming along, they can be more definitive?
When I had a reoccurrence after HIFU my PSMA PET scan showed two bone mets ( T1 spine and third rib). I had SBRT to both in hope of abscopal affect and although they both responded 6 months later I had numerous mets esp on my spine so had to start systemic treatment.
I opted to throw the lot at it with Degarelix and 3 lots of early Lu-177 ( had to travel as it’s non standard of care for hormone sensitive). I followed up with 3 lots of Docetaxel m, 20 Rounds of Vmat radiation to prod state and pelvic area and 2 x Brachi boost ( again non- standard of care). I then added Aparatatone and after 7 months of intensive treatment went to undetectable PSA plus I’ve had NED on last 2 bone scans.
The Lu-177 was the easiest treatment for me and the Hormone therapy the hardest. I am still on hormone therapy so no idea what did what.
In addition I volunteered for the OVM-200 cancer vaccine under the phase 1 ‘first in human’ clinical trial and have had three doses of that .
No regrets having Lu-177 for me as I didn’t want to leave anything on the table but I know It’s not always a success and no idea if it helped!
Good luck
Holy cow! That is an amazing story.
what did your PSMA Pylarify scan show in mid January? Last month.
It showed 2 major mets, 1 at T-6 & 1 on my hip. Maybe some very small ones on some ribs? I think my MO thinks I am beyond Oligomestatic & thinks I should do the trial with 177Lu-PSMA-I&T (if selected), before Chemo. This version of Pluvicto, is lower dosage & meant for lower volume mets., I think?
Thank you for posting this link . It answered questions we had about Pluvicto treatment and production. DH had first infusion on December 21 with second scheduled for February 3. After flying 950 miles for the treatment, his appointment was delayed because of supply issues.
Now he is scheduled for February 17 and we are a bit skeptical if it will be available. He’s making the trip alone this time because of $$$ and we have an elderly dog to care for. It’s the first treatment in almost 10 years that I haven’t attended with him. Here’s hoping Novartis comes through this time.
Sorry, you had to go through all of the hassle! Hopefully, the NJ facility has gained Novartis's approval, by now? I saw in the other thread you posted, that a response was made that the NJ facility didn't pass muster, but that was last Spring.
I am doing a screening for a trial with 177Lu-PSMA-I&T, 2/14/23 (what a way to spend V-Day w/wife 😘) at St. Louis U & will try to ask where they are getting their supplies.
Information about a RO for treatment following BCR at a proton beam therapy facility
Advice for men who are about to start hormone treatment for metastatic prostate cancer?
A NEW COMBINED DRUG PSMA-DOC HAS BEEN CREATED FOR THE TREATMENT OF PROSTATE CANCER!Galeterone for the treatment of advanced prostate cancer: the evidence to date
a trial for prostate cancer treatment involving thalidomide to start later this year
