Statin with ADT

[Teufelshunde]

Dont remember seeing this posted yet. Seems statins can help us with PC and have seen a few of these recently.

renalandurologynews.com/hom...

[SViking]

Thanks that’s very interesting. There are quite a few different types of statins. Which Statin works the best?

[Purple-Bike in reply to SViking]

I use Pitavaststin, per the articles referenced by Bigm789 four and five months ago.

[RugbyVLS]

I've seen some other reports on this that seem to indicate the same thing. There's also a report that simvistatin can help with radiosensitivity of cancer cells if undergoing radiation treatment. MO and RO still want to see more evidence. Not SOC yet.

One caution: If you take Nubeqa, there can be some serious drug interaction. Cardiologist was not aware and it took some pushing to get MO to look at this. Finally, the PA to the MO did the research and came to the same conclusion.

[podsart in reply to RugbyVLS]

what drug interactions re Nubeqa have u found/heard of?

[swwags in reply to podsart]

reference.medscape.com/drug...

Enter the drugs you take here and you'll get an idea

[podsart in reply to swwags]

first glance statins is a big problem

[RugbyVLS]

link.springer.com/content/p...

[RugbyVLS]

Rosuvastatin exposure increased 5.2-fold with darolutamide because of BCRP and probably also OATPB1/OATPB3 inhibition.

[Teufelshunde in reply to RugbyVLS]

Be careful with Rosuvastatin, especially high dose. My wife was on that and we both changed to atorvastatin. Why risk it when other statins do just as well as far as cholesterol, etc.

renalandurologynews.com/hom...

[Currumpaw]

John Hopkins recently (?) posted a study that combining Pitavastatin with Metformin was quite effective. It is on the net and I have replied about it or even posted here before,

Currumpaw

[Teufelshunde in reply to Currumpaw]

I know I have seen some recently. That must have been one of the.

[GeorgeGlass in reply to Currumpaw]

can you share that study currumpaw?

Thanks

George

[Currumpaw in reply to GeorgeGlass]

Hey George!

Type this in your search bar. "pitavastatin cancer study by john hopkins". It will take you to many articles. Pitavastatin is expensive in the US.

Currumpaw

[Currumpaw in reply to GeorgeGlass]

George,

Statins Starve Cancer Cells to Death - Johns Hopkins Medicine …

hopkinsmedicine.org/news/ne.....

Another one --

Researchers design 'prodrug' that targets cancer cells' big appetite ...

sciencedaily.com/releases/2...

Nov 16, 2022 · Johns Hopkins Medicine researchers have revamped an anti-cancer drug to better target cancer cells and leave healthy tissues unharmed. Scientists have dubbed this type of targeted approach a ...

My computer crashed. I haven't transferred data from the previous computer's hard drive.

Currumpaw

Edit: Copy at least both lines the in the black font as well as the line in the blue font below it to access the articles.