I updated my profile. First appointment at Duke was September 2021. DR recommended iADT with Orgovyx; October -May. Good response. First PSA after stopping Orgovyx was 1.21 in September. DR said return in 3 months for PSMA PET scan and restart Orgovyx when PSA rises back to 7. This was PSA just before starting Orgovyx. PSA is now 11.27 and there is one positive lesion on C2. I meet with DR this Thursday. Am I correct that triplet therapy is what I need and probably radiation? I know Duke is supposed to be one of the best but is this DR too passive?
I appreciate any comments.
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Triple therapy offers a survival advantage in the novo metastatic castration sensitive cancer.Your cancer is oligometastatic castration sensitive PC with several prior therapies.
Discuss treatment with continuous ADT plus abiraterone or ADT plus other new antiandrogens.
The most recent data from the PRESIDE RCT suggests that triplet may effective in cases like yours (they failed Xtandi first). This confirms what was found in the CHEIRON RCT:
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