Lesion on Femur detected in PSMA PET Scan after 3 years of PCa Diagnosis

[ANILKUMAR-FARMING]

My Dad (now 65 yrs age) was diagnosed with Prostrate Cancer in November 2019.

Stage T3bN1M0 Gleason Score 8, Few pelvic nodes involved

Avoided Radical Prostectomy

We finished with VMAT radiation therapy on 14 Feb. 2020. Therapy details as follows-

1. Prostate + Seminal Vesicles - 68 Gy / 25 fractions / 5 weeks

2. Pelvic Lymphatics - 44 Gy / 20 Fractions / 4 weeks.

Furthermore, we have given 10 shots of Lupride 22.5 mg - 3 month depot (ADT) from 18-11-2019

He was on ADT holidays starting from 16 May 2022.

PSA rose from 0.156 to 2.1 after 6 months of ADT holidays due to which Dr suggested of PSMA PET SCAN

PSMA Scan showed new lesion on right femur bone. (Dad had no pain in that area)

Hence, Orchidectomy was done on 15 November 2022

Now, He is taking SBRT radiation -5 fractions to lesion on femur bone.

Furthermore, Doctor would be starting Tab Arbiraterone(Zytiga) post Radiation.

Other medications that are ongoing are-

1. Tab Alfoo - (0-0-1 )For Urine Flow

2. Tab Thyronorm 100 ucg - (1-0-0 ) For Hypothyroidism

Also, he walks 5 km daily.

Is there anything else that needs to done to slow the overall progression of disease?

What can be done to decrease side effects of Orchidectomy on Bone density ?

Thanks in advance

[Tall_Allen]

What is his bone mineral density on a DEXA scan?

[ANILKUMAR-FARMING in reply to Tall_Allen]

Doctor has not yet asked to do the Dexa scan. So don't have the numbers as of now.

But, I had read that ADT causes decrease in Bone Mass Density so was concerned

[Tall_Allen in reply to ANILKUMAR-FARMING]

don’t do anything (other than exercise) without a Dexa scan.