I had a bad reaction to Doxataxel that put me in the ICU. This my first experience with chemotherapy. I had a nuclear stress test 2 days before and was told by the MO and cardiologist that there would be no problems. The nuclear test results were all negative. The test was given to check for heart damage from Afib.Anyone have any problems like this?
All the best to everyone.
Tom
What was the problem that put you in the ICU?
As soon as they started to give me the chemo I flipped out and woke up in the ICU. He said they brought me back by giving me Benadryl immediately.
You had an anaphylactic shock which is a known complication of docetaxel. See FDA black box warning
accessdata.fda.gov/drugsatf...
"Severe hypersensitivity reactions characterized by generalized rash/erythema,hypotension and/or bronchospasm, or very rarely fatal anaphylaxis, have been reported in patients who received a 3-day dexamethasone premedication.Hypersensitivity reactions require immediate discontinuation of the Docetaxel Injection infusion and administration of appropriate therapy [see Warning and Precautions (5.4)]. Docetaxel Injection must not be given to patients who have a history of severe hypersensitivity reactions to docetaxel or to other drugs formulated with polysorbate 80 [see Contraindications (4)]"
It does not have anything to do with your AF or any other heart problem.
It may preclude continuing with docetaxel therapy. Perhaps they could change to Jevtana or paclitaxel and premedicate adequately with anti allergic drugs including steroids.
It caused AFib? Dysrhythmias were reported by 8% (6% in the control group), but they were never serious enough to require hospitalization.
No ta I had the AFib the first time was early September and again in early October both times it cleared up on its own but I am on Eliquis blood thinner.
Afib is the only adverse reaction you mentioned in your post. So what are you saying the adverse reaction to docetaxel was?
The hospital report says hypersensitivity reaction. I went into shock
First docetaxel + carboplatin; my reaction
Provenge Reaction 
lupron 4th shot strong reaction
Zytiga Reaction? 
Reaction to doxetaxil 
